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Protein

Complement C1q tumor necrosis factor-related protein 6

Gene

C1qtnf6

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Complement C1q tumor necrosis factor-related protein 6
Gene namesi
Name:C1qtnf6
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1307057. C1qtnf6.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 263239Complement C1q tumor necrosis factor-related protein 6PRO_0000320085Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi76 – 761N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ3T1I2.
PRIDEiQ3T1I2.

Expressioni

Gene expression databases

GenevisibleiQ3T1I2. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009551.

Structurei

3D structure databases

ProteinModelPortaliQ3T1I2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini82 – 12342Collagen-likeAdd
BLAST
Domaini124 – 263140C1qPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 C1q domain.PROSITE-ProRule annotation
Contains 1 collagen-like domain.Curated

Keywords - Domaini

Collagen, Signal

Phylogenomic databases

eggNOGiENOG410IKX5. Eukaryota.
ENOG410XQIM. LUCA.
GeneTreeiENSGT00760000118830.
HOGENOMiHOG000101544.
HOVERGENiHBG108220.
InParanoidiQ3T1I2.
KOiK19470.
OMAiKETYVHV.
OrthoDBiEOG71CFMS.
PhylomeDBiQ3T1I2.
TreeFamiTF329591.

Family and domain databases

Gene3Di2.60.120.40. 1 hit.
InterProiIPR001073. C1q_dom.
IPR008160. Collagen.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view]
PfamiPF00386. C1q. 1 hit.
PF01391. Collagen. 1 hit.
[Graphical view]
PRINTSiPR00007. COMPLEMNTC1Q.
SMARTiSM00110. C1Q. 1 hit.
[Graphical view]
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiPS50871. C1Q. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3T1I2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVIMGTASL GSIWAVFLLP LVFGVPTEEP TFGESVASHL PKNCQRCCDP
60 70 80 90 100
EDPLSPADTV NAVPPYVLPE VRPYINITIL KGDKGDRGPS GTPGKPGKNG
110 120 130 140 150
TRGDRGSQGI KGDKGQAGSP GSSCQTHYSA FSVGRKTGLH SSENFLSLLF
160 170 180 190 200
DRVFVNTDGH FDMATGRFVA PLRGLYFFSL NVHSWNYKET YVHIVHNEQA
210 220 230 240 250
VVILYAQPSE RSIMQSQSVM LPLVPGDYVW VRLFKREREN GIYSDDMDTY
260
ITFSGHLIKA EDN
Length:263
Mass (Da):28,973
Last modified:October 11, 2005 - v1
Checksum:iB9352FD2E605BB7C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC101907 mRNA. Translation: AAI01908.1.
RefSeqiNP_001030104.1. NM_001034932.1.
UniGeneiRn.17708.

Genome annotation databases

EnsembliENSRNOT00000009551; ENSRNOP00000009551; ENSRNOG00000007300.
GeneIDi315114.
KEGGirno:315114.
UCSCiRGD:1307057. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC101907 mRNA. Translation: AAI01908.1.
RefSeqiNP_001030104.1. NM_001034932.1.
UniGeneiRn.17708.

3D structure databases

ProteinModelPortaliQ3T1I2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009551.

Proteomic databases

PaxDbiQ3T1I2.
PRIDEiQ3T1I2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000009551; ENSRNOP00000009551; ENSRNOG00000007300.
GeneIDi315114.
KEGGirno:315114.
UCSCiRGD:1307057. rat.

Organism-specific databases

CTDi114904.
RGDi1307057. C1qtnf6.

Phylogenomic databases

eggNOGiENOG410IKX5. Eukaryota.
ENOG410XQIM. LUCA.
GeneTreeiENSGT00760000118830.
HOGENOMiHOG000101544.
HOVERGENiHBG108220.
InParanoidiQ3T1I2.
KOiK19470.
OMAiKETYVHV.
OrthoDBiEOG71CFMS.
PhylomeDBiQ3T1I2.
TreeFamiTF329591.

Miscellaneous databases

NextBioi668683.
PROiQ3T1I2.

Gene expression databases

GenevisibleiQ3T1I2. RN.

Family and domain databases

Gene3Di2.60.120.40. 1 hit.
InterProiIPR001073. C1q_dom.
IPR008160. Collagen.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view]
PfamiPF00386. C1q. 1 hit.
PF01391. Collagen. 1 hit.
[Graphical view]
PRINTSiPR00007. COMPLEMNTC1Q.
SMARTiSM00110. C1Q. 1 hit.
[Graphical view]
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiPS50871. C1Q. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Prostate.

Entry informationi

Entry nameiC1QT6_RAT
AccessioniPrimary (citable) accession number: Q3T1I2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: October 11, 2005
Last modified: December 9, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.