Reviewed, UniProtKB/Swiss-Prot Q3T186 (RPIA_BOVIN)

Names and origin

Protein names

Recommended name:
    Ribose-5-phosphate isomerase
    EC=5.3.1.6
Alternative name(s):
    Phosphoriboisomerase

Gene names

Name:

RPIA

Organism

Bos taurus (Bovine)

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	264 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 264	›264	Ribose-5-phosphate isomerase		PRO_0000284953
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	Q3T186-1 [UniParc]. Last modified July 24, 2007. Version 2. Checksum: C940FDCCD985646D	FASTA	264	28,753
	10 20 30 40 50 60 LPGRSQFGAG STSTGVRETN IVCPGPSAMS KAEEAKKLAG RAAVENHVRN NQVLGIGSGS 70 80 90 100 110 120 TIVHAVQRIA ERVEQENLKL VCIPTSFQAR QLILQYGLTL SDLDRHPEID LAIDGADEVD 130 140 150 160 170 180 ADLNLIKGGG GCLTQEKIVA GNASRFIVIA DFRKDSKNLG DQWHKGIPIE VIPMAYVPVS 190 200 210 220 230 240 RTVTQKFGGV IELRMAVNKA GPVVTDNGNF ILDWKFDRVH KWSEVNIAIK MIPGVVDTGL 250 260 FINMAERVYF GMQDGSVNMR EKPF

References

[1]	NIH - Mammalian Gene Collection (MGC) project Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Crossbred X Angus. Tissue: Ileum.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC102070 mRNA. Translation: AAI02071.1. Different initiation.
IPI	IPI00690345.
RefSeq	NP_001030510.2.
UniGene	Bt.20216
3D structure databases
SMR	Q3T186. Positions 33-263.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3T186.
Genome annotation databases
Ensembl	ENSBTAT00000003719; ENSBTAP00000003719; ENSBTAG00000002866; Bos taurus. [Genome view]
GeneID	613376.
KEGG	bta:613376.
Organism-specific databases
CTD	613376.
Phylogenomic databases
eggNOG	maNOG09513.
HOVERGEN	Q3T186.
InParanoid	Q3T186.
OMA	DADFGEI.
OrthoDB	EOG94J53H.
Enzyme and pathway databases
BRENDA	5.3.1.6. 251.
Family and domain databases
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. [Graphical view]
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. rpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_BOVIN

Accession

Primary (citable) accession number: Q3T186

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 2007
Last sequence update:	July 24, 2007
Last modified:	February 9, 2010
This is version 31 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)