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Q3T100

- MGST3_BOVIN

UniProt

Q3T100 - MGST3_BOVIN

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Protein
Microsomal glutathione S-transferase 3
Gene
MGST3
Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Also functions as a glutathione peroxidase By similarity.

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

  1. glutathione peroxidase activity Source: RefGenome
  2. glutathione transferase activity Source: RefGenome

GO - Biological processi

  1. metabolic process Source: GOC
  2. oxidation-reduction process Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Enzyme and pathway databases

ReactomeiREACT_223659. Glutathione conjugation.

Names & Taxonomyi

Protein namesi
Recommended name:
Microsomal glutathione S-transferase 3 (EC:2.5.1.18)
Short name:
Microsomal GST-3
Gene namesi
Name:MGST3
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 3

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei9 – 2921Helical; Reviewed prediction
Add
BLAST
Transmembranei71 – 9121Helical; Reviewed prediction
Add
BLAST
Transmembranei120 – 14021Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. endoplasmic reticulum Source: RefGenome
  2. endoplasmic reticulum membrane Source: UniProtKB-SubCell
  3. integral component of membrane Source: UniProtKB-KW
  4. nuclear envelope Source: RefGenome
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, Microsome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 152152Microsomal glutathione S-transferase 3
PRO_0000246088Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi151 – 1511S-palmitoyl cysteine By similarity

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PRIDEiQ3T100.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000013559.

Structurei

3D structure databases

ProteinModelPortaliQ3T100.

Family & Domainsi

Sequence similaritiesi

Belongs to the MAPEG family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG84007.
GeneTreeiENSGT00390000008608.
HOGENOMiHOG000116372.
HOVERGENiHBG052472.
InParanoidiQ3T100.
KOiK00799.
OMAiEYGFVIL.
OrthoDBiEOG7PCJKH.
TreeFamiTF105328.

Family and domain databases

Gene3Di1.20.120.550. 1 hit.
InterProiIPR023352. MAPEG-like_dom.
IPR001129. Membr-assoc_MAPEG.
[Graphical view]
PfamiPF01124. MAPEG. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3T100-1 [UniParc]FASTAAdd to Basket

« Hide

MAVLSKEYGF VILTGAASFL MVTHLAINVS KARKKYKVEY PTMYSTDPEN    50
GHIFNCIQRA HQNTLEVYPP FLFFLAVGGV YHPRIVSGLG LAWIVGRVLY 100
AYGYYTGEPR KRQRGALSFI ALIGLMGTTV CSAFQHLGWV RTGLNSGCKS 150
CH 152
Length:152
Mass (Da):16,884
Last modified:October 11, 2005 - v1
Checksum:i440C63094FD1999E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC102190 mRNA. Translation: AAI02191.1.
RefSeqiNP_001030218.1. NM_001035046.2.
XP_005203478.1. XM_005203421.1.
UniGeneiBt.1157.

Genome annotation databases

EnsembliENSBTAT00000013559; ENSBTAP00000013559; ENSBTAG00000010265.
GeneIDi507346.
KEGGibta:507346.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC102190 mRNA. Translation: AAI02191.1 .
RefSeqi NP_001030218.1. NM_001035046.2.
XP_005203478.1. XM_005203421.1.
UniGenei Bt.1157.

3D structure databases

ProteinModelPortali Q3T100.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000013559.

Proteomic databases

PRIDEi Q3T100.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000013559 ; ENSBTAP00000013559 ; ENSBTAG00000010265 .
GeneIDi 507346.
KEGGi bta:507346.

Organism-specific databases

CTDi 4259.

Phylogenomic databases

eggNOGi NOG84007.
GeneTreei ENSGT00390000008608.
HOGENOMi HOG000116372.
HOVERGENi HBG052472.
InParanoidi Q3T100.
KOi K00799.
OMAi EYGFVIL.
OrthoDBi EOG7PCJKH.
TreeFami TF105328.

Enzyme and pathway databases

Reactomei REACT_223659. Glutathione conjugation.

Miscellaneous databases

NextBioi 20868020.

Family and domain databases

Gene3Di 1.20.120.550. 1 hit.
InterProi IPR023352. MAPEG-like_dom.
IPR001129. Membr-assoc_MAPEG.
[Graphical view ]
Pfami PF01124. MAPEG. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus.
    Tissue: Ileum.

Entry informationi

Entry nameiMGST3_BOVIN
AccessioniPrimary (citable) accession number: Q3T100
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: October 11, 2005
Last modified: September 3, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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