Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q3T100

- MGST3_BOVIN

UniProt

Q3T100 - MGST3_BOVIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Microsomal glutathione S-transferase 3

Gene

MGST3

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Also functions as a glutathione peroxidase.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

  1. glutathione peroxidase activity Source: RefGenome
  2. glutathione transferase activity Source: RefGenome

GO - Biological processi

  1. metabolic process Source: GOC
  2. oxidation-reduction process Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Enzyme and pathway databases

ReactomeiREACT_223659. Glutathione conjugation.

Names & Taxonomyi

Protein namesi
Recommended name:
Microsomal glutathione S-transferase 3 (EC:2.5.1.18)
Short name:
Microsomal GST-3
Gene namesi
Name:MGST3
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 3

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: RefGenome
  2. extracellular vesicular exosome Source: Ensembl
  3. integral component of membrane Source: UniProtKB-KW
  4. nuclear envelope Source: RefGenome
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, Microsome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 152152Microsomal glutathione S-transferase 3PRO_0000246088Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi151 – 1511S-palmitoyl cysteineBy similarity

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PRIDEiQ3T100.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000013559.

Structurei

3D structure databases

ProteinModelPortaliQ3T100.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei9 – 2921HelicalSequence AnalysisAdd
BLAST
Transmembranei71 – 9121HelicalSequence AnalysisAdd
BLAST
Transmembranei120 – 14021HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the MAPEG family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG84007.
GeneTreeiENSGT00390000008608.
HOGENOMiHOG000116372.
HOVERGENiHBG052472.
InParanoidiQ3T100.
KOiK00799.
OMAiEYGFVIL.
OrthoDBiEOG7PCJKH.
TreeFamiTF105328.

Family and domain databases

Gene3Di1.20.120.550. 1 hit.
InterProiIPR023352. MAPEG-like_dom.
IPR001129. Membr-assoc_MAPEG.
[Graphical view]
PfamiPF01124. MAPEG. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3T100 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVLSKEYGF VILTGAASFL MVTHLAINVS KARKKYKVEY PTMYSTDPEN
60 70 80 90 100
GHIFNCIQRA HQNTLEVYPP FLFFLAVGGV YHPRIVSGLG LAWIVGRVLY
110 120 130 140 150
AYGYYTGEPR KRQRGALSFI ALIGLMGTTV CSAFQHLGWV RTGLNSGCKS

CH
Length:152
Mass (Da):16,884
Last modified:October 11, 2005 - v1
Checksum:i440C63094FD1999E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC102190 mRNA. Translation: AAI02191.1.
RefSeqiNP_001030218.1. NM_001035046.2.
XP_005203478.1. XM_005203421.1.
UniGeneiBt.1157.

Genome annotation databases

EnsembliENSBTAT00000013559; ENSBTAP00000013559; ENSBTAG00000010265.
GeneIDi507346.
KEGGibta:507346.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC102190 mRNA. Translation: AAI02191.1 .
RefSeqi NP_001030218.1. NM_001035046.2.
XP_005203478.1. XM_005203421.1.
UniGenei Bt.1157.

3D structure databases

ProteinModelPortali Q3T100.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000013559.

Proteomic databases

PRIDEi Q3T100.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000013559 ; ENSBTAP00000013559 ; ENSBTAG00000010265 .
GeneIDi 507346.
KEGGi bta:507346.

Organism-specific databases

CTDi 4259.

Phylogenomic databases

eggNOGi NOG84007.
GeneTreei ENSGT00390000008608.
HOGENOMi HOG000116372.
HOVERGENi HBG052472.
InParanoidi Q3T100.
KOi K00799.
OMAi EYGFVIL.
OrthoDBi EOG7PCJKH.
TreeFami TF105328.

Enzyme and pathway databases

Reactomei REACT_223659. Glutathione conjugation.

Miscellaneous databases

NextBioi 20868020.

Family and domain databases

Gene3Di 1.20.120.550. 1 hit.
InterProi IPR023352. MAPEG-like_dom.
IPR001129. Membr-assoc_MAPEG.
[Graphical view ]
Pfami PF01124. MAPEG. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus.
    Tissue: Ileum.

Entry informationi

Entry nameiMGST3_BOVIN
AccessioniPrimary (citable) accession number: Q3T100
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: October 11, 2005
Last modified: October 29, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3