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Q3T0V9 (DEOC_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative deoxyribose-phosphate aldolase
Short name=DERA
EC=4.1.2.4
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase
Phosphodeoxyriboaldolase
Short name=Deoxyriboaldolase
Gene names
Name:DERA
OrganismBos taurus (Bovine)
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity.

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.

Ontologies

Keywords
   LigandSchiff base
   Molecular functionLyase
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processdeoxyribonucleotide catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular functiondeoxyribose-phosphate aldolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 318318Putative deoxyribose-phosphate aldolase
PRO_0000283798

Sites

Active site2181Schiff-base intermediate with acetaldehyde By similarity
Active site2541 By similarity

Amino acid modifications

Modified residue2611Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q3T0V9 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: DE1545BD35BCB714

FASTA31835,246
        10         20         30         40         50         60 
MSAHQQGTEL DLSWISKIQV NKPAVLRRAE QIQARRPVKK EWQAAWLLKA VTCIDLTTLS 

        70         80         90        100        110        120 
GDDTASNIQR LCYKAKYPIR EDLLKALNMH DKGITTAAVC VYPARVCDAV RALKAAGCDI 

       130        140        150        160        170        180 
PVASVATGFP AAQTHLKTRL EEIRLAVEDG ATEIDVVINR TLVLTGQWKA LYDEIRQFRK 

       190        200        210        220        230        240 
ACGEAHLKTI LATGELGSLT NVYKASMIAM MAGSDFIKTS TGKETVNATF PVAIVMLRAI 

       250        260        270        280        290        300 
RDFFWKTGNK VGFKPAGGIR SAKDSLVWLS LIKEELGDEW MKPELFRIGA STLLADIERQ 

       310 
IYHHVTGRYA AYHDLPMS

« Hide

References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Crossbred X Angus.
Tissue: Ileum.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC102242 mRNA. Translation: AAI02243.1.
IPIIPI00716663.
RefSeqNP_001069496.1. NM_001076028.1.
UniGeneBt.48820.

3D structure databases

HSSPHSSP built from PDB template 1O0Y based on UniProtKB Q9X1P5.
ProteinModelPortalQ3T0V9.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3T0V9.

Proteomic databases

PRIDEQ3T0V9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSBTAT00000007367; ENSBTAP00000007367; ENSBTAG00000022167.
GeneID534558.
KEGGbta:534558.

Organism-specific databases

CTD51071.

Phylogenomic databases

eggNOGmaNOG14180.
GeneTreeENSGT00390000007878.
HOVERGENHBG030164.
InParanoidQ3T0V9.
OMADTPGKVR.
OrthoDBEOG46T323.
PhylomeDBQ3T0V9.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/AroFGH_arch.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01619.
PANTHERPTHR10889. DeoC. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. DeoC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDEOC_BOVIN
AccessionPrimary (citable) accession number: Q3T0V9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: October 11, 2005
Last modified: November 16, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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