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Reviewed, UniProtKB/Swiss-Prot Q3T0V9 (DEOC_BOVIN)

Last modified February 9, 2010. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Putative deoxyribose-phosphate aldolase
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase
      Short name=Deoxyriboaldolase
      Short name=DERA
Gene names
Name: DERA
OrganismBos taurus (Bovine)
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

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Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.

Sequence similarities

Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily.

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Ontologies

Keywords
   LigandSchiff base
   Molecular functionLyase
   PTMPhosphoprotein
Gene Ontology (GO)
   Biological processdeoxyribonucleotide catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular functiondeoxyribose-phosphate aldolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 318318Putative deoxyribose-phosphate aldolase
PRO_0000283798

Sites

Active site2181Schiff-base intermediate with acetaldehyde By similarity
Active site2541 By similarity

Amino acid modifications

Modified residue2611Phosphoserine By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q3T0V9-1 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: DE1545BD35BCB714

FASTA31835,246
        10         20         30         40         50         60 
MSAHQQGTEL DLSWISKIQV NKPAVLRRAE QIQARRPVKK EWQAAWLLKA VTCIDLTTLS 

        70         80         90        100        110        120 
GDDTASNIQR LCYKAKYPIR EDLLKALNMH DKGITTAAVC VYPARVCDAV RALKAAGCDI 

       130        140        150        160        170        180 
PVASVATGFP AAQTHLKTRL EEIRLAVEDG ATEIDVVINR TLVLTGQWKA LYDEIRQFRK 

       190        200        210        220        230        240 
ACGEAHLKTI LATGELGSLT NVYKASMIAM MAGSDFIKTS TGKETVNATF PVAIVMLRAI 

       250        260        270        280        290        300 
RDFFWKTGNK VGFKPAGGIR SAKDSLVWLS LIKEELGDEW MKPELFRIGA STLLADIERQ 

       310 
IYHHVTGRYA AYHDLPMS

« Hide

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References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Crossbred X Angus.
Tissue: Ileum.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC102242 mRNA. Translation: AAI02243.1.
IPIIPI00716663.
RefSeqNP_001069496.1.
UniGeneBt.48820

3D structure databases

HSSPHSSP built from PDB template 1O0Y based on UniProtKB Q9X1P5.
SMRQ3T0V9. Positions 48-303.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3T0V9.

Genome annotation databases

EnsemblENSBTAT00000007367; ENSBTAP00000007367; ENSBTAG00000022167; Bos taurus. [Genome view]
GeneID534558.
KEGGbta:534558.

Organism-specific databases

CTD534558.

Phylogenomic databases

eggNOGmaNOG14180.
HOVERGENQ3T0V9.
InParanoidQ3T0V9.
OMAIDIVITR.
OrthoDBEOG9V7226.
PhylomeDBQ3T0V9.

Enzyme and pathway databases

BRENDA4.1.2.4. 251.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/AroFGH_arch.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHERPTHR10889. DeoC. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. deoC. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameDEOC_BOVIN
AccessionPrimary (citable) accession number: Q3T0V9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: October 11, 2005
Last modified: February 9, 2010
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents