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Protein

DAZ-associated protein 2

Gene

DAZAP2

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
DAZ-associated protein 2
Alternative name(s):
Deleted in azoospermia-associated protein 2
Gene namesi
Name:DAZAP2
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Subcellular locationi

  • Cytoplasm By similarity
  • Nucleus By similarity

  • Note: Predominantly nuclear in macrophages, stimulation of IL17RB with its ligand IL17E induces accumulation in the cytoplasm.By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 168168DAZ-associated protein 2PRO_0000285817Add
BLAST

Post-translational modificationi

Ubiquitinated by SMURF2, leading to proteasomal degradation.By similarity

Keywords - PTMi

Ubl conjugation

Proteomic databases

PaxDbiQ3T0K9.

Interactioni

Subunit structurei

Interacts with DAZ and DAZL. Interacts with SOX6. Interacts with IL17RB. May interact with FAM168B.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000002573.

Structurei

3D structure databases

ProteinModelPortaliQ3T0K9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi8 – 134127Pro-richAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IVQC. Eukaryota.
ENOG4111N7I. LUCA.
GeneTreeiENSGT00390000000685.
HOGENOMiHOG000007683.
HOVERGENiHBG051300.
InParanoidiQ3T0K9.
OMAiAYSEIYQ.
OrthoDBiEOG77HDG0.
TreeFamiTF329672.

Family and domain databases

InterProiIPR022730. DAZ_assoc-2.
[Graphical view]
PfamiPF11029. DAZAP2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3T0K9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSKGQYPTQ PTYPVQPPGN PVYPQTLHLP QAPPYTDAPP AYSELYRPSF
60 70 80 90 100
VHPGAATVPT MSAAFPGASL YLPMAQSVAV GPLGSTIPMA YYPVGPIYPP
110 120 130 140 150
GSTVLVEGGY DAGARFGAGA TAGNIPPPPP GCPPNAAQLA VMQGANVLVT
160
QRKGNFFMGG SDGGYTIW
Length:168
Mass (Da):17,319
Last modified:October 11, 2005 - v1
Checksum:i49F1B6D281E24AAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102352 mRNA. Translation: AAI02353.1.
RefSeqiNP_001029873.1. NM_001034701.1.
UniGeneiBt.52888.

Genome annotation databases

EnsembliENSBTAT00000002573; ENSBTAP00000002573; ENSBTAG00000004349.
GeneIDi540286.
KEGGibta:540286.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102352 mRNA. Translation: AAI02353.1.
RefSeqiNP_001029873.1. NM_001034701.1.
UniGeneiBt.52888.

3D structure databases

ProteinModelPortaliQ3T0K9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000002573.

Proteomic databases

PaxDbiQ3T0K9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000002573; ENSBTAP00000002573; ENSBTAG00000004349.
GeneIDi540286.
KEGGibta:540286.

Organism-specific databases

CTDi9802.

Phylogenomic databases

eggNOGiENOG410IVQC. Eukaryota.
ENOG4111N7I. LUCA.
GeneTreeiENSGT00390000000685.
HOGENOMiHOG000007683.
HOVERGENiHBG051300.
InParanoidiQ3T0K9.
OMAiAYSEIYQ.
OrthoDBiEOG77HDG0.
TreeFamiTF329672.

Family and domain databases

InterProiIPR022730. DAZ_assoc-2.
[Graphical view]
PfamiPF11029. DAZAP2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus.
    Tissue: Ileum.

Entry informationi

Entry nameiDAZP2_BOVIN
AccessioniPrimary (citable) accession number: Q3T0K9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: October 11, 2005
Last modified: June 8, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.