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Protein

Cytochrome c oxidase subunit 7A-related protein, mitochondrial

Gene

COX7A2L

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the regulation of oxidative phosphorylation and energy metabolism (By similarity). Necessary for the assembly of mitochondrial respiratory supercomplex (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 7A-related protein, mitochondrial
Alternative name(s):
Cytochrome c oxidase subunit VIIa-related protein
Gene namesi
Name:COX7A2L
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 11

Organism-specific databases

VGNCiVGNC:27640 COX7A2L

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 55MitochondrionSequence analysisAdd BLAST55
ChainiPRO_000024732656 – 114Cytochrome c oxidase subunit 7A-related protein, mitochondrialAdd BLAST59

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei69N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ3T061
PeptideAtlasiQ3T061
PRIDEiQ3T061

Expressioni

Gene expression databases

BgeeiENSBTAG00000000705

Interactioni

Subunit structurei

Interacts with the mitochondrial respiratory supercomplex.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000000943

Structurei

3D structure databases

ProteinModelPortaliQ3T061
SMRiQ3T061
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c oxidase VIIa family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410IYMH Eukaryota
ENOG41120Z9 LUCA
GeneTreeiENSGT00400000022054
HOGENOMiHOG000264231
HOVERGENiHBG051095
InParanoidiQ3T061
KOiK02270
OMAiKRGYPDR
OrthoDBiEOG091G12UD
TreeFamiTF105067

Family and domain databases

CDDicd00928 Cyt_c_Oxidase_VIIa, 1 hit
Gene3Di4.10.91.10, 1 hit
InterProiView protein in InterPro
IPR003177 Cyt_c_oxidase_su7a
IPR017267 Cyt_c_oxidase_su7a-rel_mt
IPR036539 Cyt_c_oxidase_su7a_sf
PANTHERiPTHR10510 PTHR10510, 1 hit
PTHR10510:SF2 PTHR10510:SF2, 1 hit
PIRSFiPIRSF037710 COX7A-rel_mt, 1 hit
SUPFAMiSSF81419 SSF81419, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3T061-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYYKFSGFTQ KLAGAWASDA YSPQGLRPVV STEAPPIIFA TPTKLSSGPT
60 70 80 90 100
AYDYAGKNTV PELQKFFQKS DGVPIHLKRG LPDQMLYRTT MALTVGGTIY
110
CLIALYMASQ PRNK
Length:114
Mass (Da):12,544
Last modified:October 11, 2005 - v1
Checksum:i953BC55FD65E379F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102552 mRNA Translation: AAI02553.1
RefSeqiNP_001029867.1, NM_001034695.2
UniGeneiBt.49046

Genome annotation databases

EnsembliENSBTAT00000000943; ENSBTAP00000000943; ENSBTAG00000000705
GeneIDi540225
KEGGibta:540225

Similar proteinsi

Entry informationi

Entry nameiCOX7R_BOVIN
AccessioniPrimary (citable) accession number: Q3T061
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: October 11, 2005
Last modified: March 28, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health