Q3SZV3 (EF1G_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor 1-gamma
Short name=EF-1-gamma

Alternative name(s):
eEF-1B gamma

Gene names

Name:

EEF1G

Organism

Bos taurus (Bovine)

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	440 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Probably plays a role in anchoring the complex to other cellular components By similarity.
Subunit structure	EF-1 is composed of four subunits: alpha, beta, delta, and gamma By similarity.
Sequence similarities	Contains 1 EF-1-gamma C-terminal domain. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Elongation factor
PTM	Acetylation Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	eukaryotic translation elongation factor 1 complex Inferred from electronic annotation. Source: InterPro
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 440	439	Elongation factor 1-gamma		PRO_0000284654
Regions
	Domain	2 – 87	86	GST N-terminal
	Domain	88 – 216	129	GST C-terminal
	Domain	279 – 440	162	EF-1-gamma C-terminal
Amino acid modifications
	Modified residue	2	1	N-acetylalanine By similarity
	Modified residue	43	1	Phosphothreonine By similarity
	Modified residue	46	1	Phosphothreonine By similarity
	Modified residue	132	1	N6-acetyllysine By similarity
	Modified residue	147	1	N6-acetyllysine By similarity
	Modified residue	437	1	N6-acetyllysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3SZV3 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 295A874E422B825C	FASTA	440	50,378
	10 20 30 40 50 60 MAAGTLYTYP ENWRAFKALI AAQYSGAQVR VLSAPPHFHF GQTNRTPEFL RKFPAGKVPA 70 80 90 100 110 120 FEGDDGFCVF ESNAIAYYVS NEELRGSTPE AAAQVVQWVS FADSDIVPPA STWVFPTLGI 130 140 150 160 170 180 MHHNKQATEN AKEEVRRILG LLDAHLKTRT FLVGERVTLA DITVVCTLLW LYKQVLEPSF 190 200 210 220 230 240 RQAFPNTNRW FLTCINQPQF RAVLGEVKLC EKMAQFDAKK FAESQPKKDT PRKEKGSREE 250 260 270 280 290 300 KLKPQAERKE GKEEKKAAAP APEEELDECE QALAAEPKAK DPFAHLPKST FVLDEFKRKY 310 320 330 340 350 360 SNEDTLSVAL PYFWDHFDKD GWSLWYSEYR FPEELTQTFM SCNLITGMFQ RLDKLRKNAF 370 380 390 400 410 420 ASVILFGTNN SSSISGVWDF RGQELAFPLS PDWQVDYESY TWRKLDPGSE ETQTLVREYF 430 440 CWEGAFQHVG KAFNQGKIFK

References

[1]	NIH - Mammalian Gene Collection (MGC) project Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Hereford. Tissue: Testis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC102691 mRNA. Translation: AAI02692.1.
IPI	IPI00706632.
RefSeq	NP_001035577.1. NM_001040487.1.
UniGene	Bt.62921.
3D structure databases
ProteinModelPortal	Q3SZV3.
SMR	Q3SZV3. Positions 279-440.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3SZV3.
Proteomic databases
PRIDE	Q3SZV3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	326581.
KEGG	bta:326581.
Organism-specific databases
CTD	1937.
Phylogenomic databases
HOVERGEN	HBG051444.
InParanoid	Q3SZV3.
OrthoDB	EOG43JC4V.
PhylomeDB	Q3SZV3.
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012336. Thioredoxin-like_fold. IPR001662. Transl_elong_EF1_G_con. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. G3DSA:3.30.70.1010. Transl_elong_EF1_G_con. 1 hit.
KO	K03233.
Pfam	PF00647. EF1G. 1 hit. PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
SUPFAM	SSF47616. GST_C_like. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit. SSF89942. Transl_elong_EF1_G_con. 1 hit.
PROSITE	PS50040. EF1G_C. 1 hit. PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EF1G_BOVIN

Accession

Primary (citable) accession number: Q3SZV3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 17, 2007
Last sequence update:	October 11, 2005
Last modified:	November 16, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program