Reviewed, UniProtKB/Swiss-Prot Q3SZV3 (EF1G_BOVIN)

Names and origin

Protein names

Recommended name:
    Elongation factor 1-gamma
      Short name=EF-1-gamma
Alternative name(s):
    eEF-1B gamma

Gene names

Name:

EEF1G

Organism

Bos taurus (Bovine)

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	440 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Probably plays a role in anchoring the complex to other cellular components By similarity.
Subunit structure	EF-1 is composed of four subunits: alpha, beta, delta, and gamma By similarity.
Sequence similarities	Contains 1 EF-1-gamma C-terminal domain. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Elongation factor
PTM	Acetylation Phosphoprotein
Gene Ontology (GO)
Biological process	translational elongation Inferred from electronic annotation. Source: InterPro
Cellular component	eukaryotic translation elongation factor 1 complex Inferred from electronic annotation. Source: InterPro
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 440	439	Elongation factor 1-gamma		PRO_0000284654
Regions
	Domain	2 – 87	86	GST N-terminal
	Domain	88 – 216	129	GST C-terminal
	Domain	279 – 440	162	EF-1-gamma C-terminal
Amino acid modifications
	Modified residue	2	1	N-acetylalanine By similarity
	Modified residue	43	1	Phosphothreonine By similarity
	Modified residue	46	1	Phosphothreonine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3SZV3-1 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 295A874E422B825C	FASTA	440	50,378
	10 20 30 40 50 60 MAAGTLYTYP ENWRAFKALI AAQYSGAQVR VLSAPPHFHF GQTNRTPEFL RKFPAGKVPA 70 80 90 100 110 120 FEGDDGFCVF ESNAIAYYVS NEELRGSTPE AAAQVVQWVS FADSDIVPPA STWVFPTLGI 130 140 150 160 170 180 MHHNKQATEN AKEEVRRILG LLDAHLKTRT FLVGERVTLA DITVVCTLLW LYKQVLEPSF 190 200 210 220 230 240 RQAFPNTNRW FLTCINQPQF RAVLGEVKLC EKMAQFDAKK FAESQPKKDT PRKEKGSREE 250 260 270 280 290 300 KLKPQAERKE GKEEKKAAAP APEEELDECE QALAAEPKAK DPFAHLPKST FVLDEFKRKY 310 320 330 340 350 360 SNEDTLSVAL PYFWDHFDKD GWSLWYSEYR FPEELTQTFM SCNLITGMFQ RLDKLRKNAF 370 380 390 400 410 420 ASVILFGTNN SSSISGVWDF RGQELAFPLS PDWQVDYESY TWRKLDPGSE ETQTLVREYF 430 440 CWEGAFQHVG KAFNQGKIFK

References

[1]	NIH - Mammalian Gene Collection (MGC) project Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Hereford. Tissue: Testis.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC102691 mRNA. Translation: AAI02692.1.
IPI	IPI00706632.
RefSeq	NP_001035577.1.
UniGene	Bt.62921
3D structure databases
SMR	Q3SZV3. Positions 279-440.
ModBase	Search...
Proteomic databases
PRIDE	Q3SZV3.
Genome annotation databases
Ensembl	ENSBTAG00000011843. Bos taurus. [Contig view]
GeneID	326581.
KEGG	bta:326581.
Phylogenomic databases
HOVERGEN	Q3SZV3.
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR001662. Transl_elong_EF1_G_con. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.30.70.1010. Transl_elong_EF1_G_con. 1 hit.
Pfam	PF00647. EF1G. 1 hit. PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
ProDom	PD006217. EF1_G. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS50040. EF1G_C. 1 hit. PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EF1G_BOVIN

Accession

Primary (citable) accession number: Q3SZV3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 17, 2007
Last sequence update:	October 11, 2005
Last modified:	June 16, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)