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Protein

Elongation factor 1-gamma

Gene

EEF1G

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probably plays a role in anchoring the complex to other cellular components.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor 1-gamma
Short name:
EF-1-gamma
Alternative name(s):
eEF-1B gamma
Gene namesi
Name:EEF1G
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002846542 – 440Elongation factor 1-gammaAdd BLAST439

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1
Modified residuei147N6-acetyllysineBy similarity1
Modified residuei212N6-acetyllysineBy similarity1
Cross-linki256Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)By similarity
Cross-linki288Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei404N6-acetyllysineBy similarity1
Modified residuei437N6-acetyllysine; alternateBy similarity1
Modified residuei437N6-malonyllysine; alternateBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiQ3SZV3.
PeptideAtlasiQ3SZV3.
PRIDEiQ3SZV3.

Interactioni

Subunit structurei

EF-1 is composed of four subunits: alpha, beta, delta, and gamma.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000015716.

Structurei

3D structure databases

ProteinModelPortaliQ3SZV3.
SMRiQ3SZV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 87GST N-terminalAdd BLAST86
Domaini88 – 216GST C-terminalAdd BLAST129
Domaini279 – 440EF-1-gamma C-terminalPROSITE-ProRule annotationAdd BLAST162

Phylogenomic databases

eggNOGiKOG0867. Eukaryota.
KOG1627. Eukaryota.
COG0625. LUCA.
HOGENOMiHOG000201196.
HOVERGENiHBG051444.
InParanoidiQ3SZV3.
KOiK03233.

Family and domain databases

Gene3Di3.30.70.1010. 1 hit.
InterProiView protein in InterPro
IPR001662. EF1B_G_C.
IPR036433. EF1B_G_C_sf.
IPR010987. Glutathione-S-Trfase_C-like.
IPR036282. Glutathione-S-Trfase_C_sf.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR036249. Thioredoxin-like_sf.
PfamiView protein in Pfam
PF00647. EF1G. 1 hit.
PF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
SMARTiView protein in SMART
SM01183. EF1G. 1 hit.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
SSF89942. SSF89942. 1 hit.
PROSITEiView protein in PROSITE
PS50040. EF1G_C. 1 hit.
PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3SZV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAGTLYTYP ENWRAFKALI AAQYSGAQVR VLSAPPHFHF GQTNRTPEFL
60 70 80 90 100
RKFPAGKVPA FEGDDGFCVF ESNAIAYYVS NEELRGSTPE AAAQVVQWVS
110 120 130 140 150
FADSDIVPPA STWVFPTLGI MHHNKQATEN AKEEVRRILG LLDAHLKTRT
160 170 180 190 200
FLVGERVTLA DITVVCTLLW LYKQVLEPSF RQAFPNTNRW FLTCINQPQF
210 220 230 240 250
RAVLGEVKLC EKMAQFDAKK FAESQPKKDT PRKEKGSREE KLKPQAERKE
260 270 280 290 300
GKEEKKAAAP APEEELDECE QALAAEPKAK DPFAHLPKST FVLDEFKRKY
310 320 330 340 350
SNEDTLSVAL PYFWDHFDKD GWSLWYSEYR FPEELTQTFM SCNLITGMFQ
360 370 380 390 400
RLDKLRKNAF ASVILFGTNN SSSISGVWDF RGQELAFPLS PDWQVDYESY
410 420 430 440
TWRKLDPGSE ETQTLVREYF CWEGAFQHVG KAFNQGKIFK
Length:440
Mass (Da):50,378
Last modified:October 11, 2005 - v1
Checksum:i295A874E422B825C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102691 mRNA. Translation: AAI02692.1.
RefSeqiNP_001035577.1. NM_001040487.2.
UniGeneiBt.62921.

Genome annotation databases

GeneIDi326581.
KEGGibta:326581.

Similar proteinsi

Entry informationi

Entry nameiEF1G_BOVIN
AccessioniPrimary (citable) accession number: Q3SZV3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: October 11, 2005
Last modified: October 25, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome