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Protein

Protein transport protein Sec23B

Gene

SEC23B

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ER-Golgi transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein transport protein Sec23B
Alternative name(s):
SEC23-related protein B
Gene namesi
Name:SEC23B
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 13

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 767766Protein transport protein Sec23BPRO_0000245344Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineBy similarity
Modified residuei564 – 5641N6-acetyllysineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ3SZN2.
PRIDEiQ3SZN2.

Interactioni

Subunit structurei

COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000024348.

Structurei

3D structure databases

ProteinModelPortaliQ3SZN2.
SMRiQ3SZN2. Positions 3-766.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SEC23/SEC24 family. SEC23 subfamily.Curated

Phylogenomic databases

eggNOGiKOG1986. Eukaryota.
COG5047. LUCA.
GeneTreeiENSGT00390000006916.
HOGENOMiHOG000231690.
HOVERGENiHBG055039.
InParanoidiQ3SZN2.
KOiK14006.
OMAiRMAFGAN.
OrthoDBiEOG72C4ZP.
TreeFamiTF300693.

Family and domain databases

Gene3Di3.40.20.10. 1 hit.
3.40.50.410. 1 hit.
InterProiIPR029006. ADF-H/Gelsolin-like_dom.
IPR007123. Gelsolin-like_dom.
IPR006900. Sec23/24_helical_dom.
IPR006896. Sec23/24_trunk_dom.
IPR012990. Sec23_24_beta_S.
IPR002035. VWF_A.
IPR006895. Znf_Sec23_Sec24.
[Graphical view]
PfamiPF00626. Gelsolin. 1 hit.
PF08033. Sec23_BS. 1 hit.
PF04815. Sec23_helical. 1 hit.
PF04811. Sec23_trunk. 1 hit.
PF04810. zf-Sec23_Sec24. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF81811. SSF81811. 1 hit.
SSF82754. SSF82754. 1 hit.
SSF82919. SSF82919. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3SZN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYLEFIQQ NEERDGVRFS WNVWPSSRLE ATRMVVPLAC LLTPLKERPD
60 70 80 90 100
LPPVQYEPVL CSRPTCKAIL NPLCQVDYRA KLWACNFCFQ RNQFPPAYAG
110 120 130 140 150
ISEVNQPAEL MPQFSTIEYV IQRGAPSPLI FLYVVDTCLE DDDLQALKES
160 170 180 190 200
LQMSLSLLPP DALVGLITFG RMVQVHELSC EGISKSYVFR GTKDLTAKQI
210 220 230 240 250
QDMLGLTKPA MPVQPMRPAQ PQERPSVSSR FLQPIHKIDM NLTDLLGELQ
260 270 280 290 300
RDPWPVPQGK RPLRSTGVAL SIAVGLLEGT FPNTGARIML FTGGPPTQGP
310 320 330 340 350
GMVVGDELKV PIRSWHDIEK DNARFMKKAT KHYEMLANRT AANGHCIDIY
360 370 380 390 400
ACALDQTGLL EMKCCPNLTG GYMVMGDSFN TSLFKQTFQR IFSKDFNGNF
410 420 430 440 450
RMAFGATLEV KTSRELKVAG AIGPCVSLNV KGPCVSENEL GVGGTSQWKI
460 470 480 490 500
CGLDPTTTLG IYFEVVNQHN APIPQGGRGA IQFVTHYQHS STQRRIRVTT
510 520 530 540 550
VARNWADVQS QLKHIEAAFD QEAAAVLMAR LGVFRAETEE GPDVLRWLDR
560 570 580 590 600
QLIRLCQKFG QYNKEDPMSF RLSDSFSLYP QFMFHLRRSP FLQVFNNSPD
610 620 630 640 650
ESSYYRHHFA RQDLTQSLIM IQPILYSYSF HGPPEPVLLD SSSILADRIL
660 670 680 690 700
LMDTFFQIVI YLGETIAQWR KAGYQDMPEY ENFKHLLQAP LDDAQEILQA
710 720 730 740 750
RFPMPRYIHT EHGGSQARFL LSKVNPSQTH NNLYAWGQET GAPILTDDVS
760
LQVFMDHLKK LAVSSAC
Length:767
Mass (Da):86,462
Last modified:October 11, 2005 - v1
Checksum:i0436D64B2F8840F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102775 mRNA. Translation: AAI02776.1.
RefSeqiNP_001029798.1. NM_001034626.2.
XP_005214413.1. XM_005214356.3.
XP_005214414.1. XM_005214357.3.
XP_005214415.1. XM_005214358.3.
XP_005214417.1. XM_005214360.3.
XP_005214418.1. XM_005214361.3.
XP_005214419.1. XM_005214362.3.
XP_005214420.1. XM_005214363.3.
XP_015329520.1. XM_015474034.1.
UniGeneiBt.48826.

Genome annotation databases

EnsembliENSBTAT00000024348; ENSBTAP00000024348; ENSBTAG00000018295.
GeneIDi535071.
KEGGibta:535071.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102775 mRNA. Translation: AAI02776.1.
RefSeqiNP_001029798.1. NM_001034626.2.
XP_005214413.1. XM_005214356.3.
XP_005214414.1. XM_005214357.3.
XP_005214415.1. XM_005214358.3.
XP_005214417.1. XM_005214360.3.
XP_005214418.1. XM_005214361.3.
XP_005214419.1. XM_005214362.3.
XP_005214420.1. XM_005214363.3.
XP_015329520.1. XM_015474034.1.
UniGeneiBt.48826.

3D structure databases

ProteinModelPortaliQ3SZN2.
SMRiQ3SZN2. Positions 3-766.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000024348.

Proteomic databases

PaxDbiQ3SZN2.
PRIDEiQ3SZN2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000024348; ENSBTAP00000024348; ENSBTAG00000018295.
GeneIDi535071.
KEGGibta:535071.

Organism-specific databases

CTDi10483.

Phylogenomic databases

eggNOGiKOG1986. Eukaryota.
COG5047. LUCA.
GeneTreeiENSGT00390000006916.
HOGENOMiHOG000231690.
HOVERGENiHBG055039.
InParanoidiQ3SZN2.
KOiK14006.
OMAiRMAFGAN.
OrthoDBiEOG72C4ZP.
TreeFamiTF300693.

Family and domain databases

Gene3Di3.40.20.10. 1 hit.
3.40.50.410. 1 hit.
InterProiIPR029006. ADF-H/Gelsolin-like_dom.
IPR007123. Gelsolin-like_dom.
IPR006900. Sec23/24_helical_dom.
IPR006896. Sec23/24_trunk_dom.
IPR012990. Sec23_24_beta_S.
IPR002035. VWF_A.
IPR006895. Znf_Sec23_Sec24.
[Graphical view]
PfamiPF00626. Gelsolin. 1 hit.
PF08033. Sec23_BS. 1 hit.
PF04815. Sec23_helical. 1 hit.
PF04811. Sec23_trunk. 1 hit.
PF04810. zf-Sec23_Sec24. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF81811. SSF81811. 1 hit.
SSF82754. SSF82754. 1 hit.
SSF82919. SSF82919. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus.
    Tissue: Ileum.

Entry informationi

Entry nameiSC23B_BOVIN
AccessioniPrimary (citable) accession number: Q3SZN2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: October 11, 2005
Last modified: June 8, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.