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Protein

Enhancer of rudimentary homolog

Gene

ERH

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May have a role in the cell cycle.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle

Names & Taxonomyi

Protein namesi
Recommended name:
Enhancer of rudimentary homolog
Gene namesi
Name:ERH
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 10

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002443902 – 104Enhancer of rudimentary homologAdd BLAST103

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineBy similarity1
Modified residuei11PhosphothreonineBy similarity1
Cross-linki12Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbiQ3SZC0.
PeptideAtlasiQ3SZC0.
PRIDEiQ3SZC0.

Expressioni

Gene expression databases

BgeeiENSBTAG00000017798.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000023664.

Structurei

3D structure databases

ProteinModelPortaliQ3SZC0.
SMRiQ3SZC0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the E(R) family.Curated

Phylogenomic databases

eggNOGiKOG1766. Eukaryota.
ENOG4111Z48. LUCA.
GeneTreeiENSGT00390000003316.
HOGENOMiHOG000246458.
HOVERGENiHBG000348.
InParanoidiQ3SZC0.
OMAiRTWSDYE.
OrthoDBiEOG091G1CHJ.
TreeFamiTF314568.

Family and domain databases

InterProiIPR000781. Enh_rudimentary.
[Graphical view]
PANTHERiPTHR12373. PTHR12373. 1 hit.
PfamiPF01133. ER. 1 hit.
[Graphical view]
PIRSFiPIRSF016393. Enh_rudimentary. 1 hit.
ProDomiPD008105. Enh_rudimentary. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF143875. SSF143875. 1 hit.
PROSITEiPS01290. ER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3SZC0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHTILLVQP TKRPEGRTYA DYESVNECME GVCKMYEEHL KRMNPNSPSI
60 70 80 90 100
TYDISQLFDF IDDLADLSCL VYRADTQTYQ PYNKDWIKEK IYVLLRRQAQ

QAGK
Length:104
Mass (Da):12,259
Last modified:October 11, 2005 - v1
Checksum:iC609AFF7F63E5279
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102967 mRNA. Translation: AAI02968.1.
RefSeqiNP_001029508.1. NM_001034336.1.
UniGeneiBt.64542.

Genome annotation databases

EnsembliENSBTAT00000023664; ENSBTAP00000023664; ENSBTAG00000017798.
GeneIDi508901.
KEGGibta:508901.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102967 mRNA. Translation: AAI02968.1.
RefSeqiNP_001029508.1. NM_001034336.1.
UniGeneiBt.64542.

3D structure databases

ProteinModelPortaliQ3SZC0.
SMRiQ3SZC0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000023664.

Proteomic databases

PaxDbiQ3SZC0.
PeptideAtlasiQ3SZC0.
PRIDEiQ3SZC0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000023664; ENSBTAP00000023664; ENSBTAG00000017798.
GeneIDi508901.
KEGGibta:508901.

Organism-specific databases

CTDi2079.

Phylogenomic databases

eggNOGiKOG1766. Eukaryota.
ENOG4111Z48. LUCA.
GeneTreeiENSGT00390000003316.
HOGENOMiHOG000246458.
HOVERGENiHBG000348.
InParanoidiQ3SZC0.
OMAiRTWSDYE.
OrthoDBiEOG091G1CHJ.
TreeFamiTF314568.

Gene expression databases

BgeeiENSBTAG00000017798.

Family and domain databases

InterProiIPR000781. Enh_rudimentary.
[Graphical view]
PANTHERiPTHR12373. PTHR12373. 1 hit.
PfamiPF01133. ER. 1 hit.
[Graphical view]
PIRSFiPIRSF016393. Enh_rudimentary. 1 hit.
ProDomiPD008105. Enh_rudimentary. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF143875. SSF143875. 1 hit.
PROSITEiPS01290. ER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiERH_BOVIN
AccessioniPrimary (citable) accession number: Q3SZC0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 11, 2005
Last modified: November 30, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.