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Protein

Translocon-associated protein subunit gamma

Gene

SSR3

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Translocon-associated protein subunit gamma
Short name:
TRAP-gamma
Alternative name(s):
Signal sequence receptor subunit gamma
Short name:
SSR-gamma
Gene namesi
Name:SSR3
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 1

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2727LumenalSequence analysisAdd
BLAST
Transmembranei28 – 4821HelicalSequence analysisAdd
BLAST
Topological domaini49 – 546CytoplasmicSequence analysis
Transmembranei55 – 7622HelicalSequence analysisAdd
BLAST
Topological domaini77 – 13559LumenalSequence analysisAdd
BLAST
Transmembranei136 – 15722HelicalSequence analysisAdd
BLAST
Topological domaini158 – 1636CytoplasmicSequence analysis
Transmembranei164 – 18421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 185185Translocon-associated protein subunit gammaPRO_0000284958Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei11 – 111PhosphoserineBy similarity
Modified residuei105 – 1051PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ3SZ87.
PeptideAtlasiQ3SZ87.
PRIDEiQ3SZ87.

Interactioni

Subunit structurei

Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000024583.

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAP-gamma family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4490. Eukaryota.
ENOG410XR1X. LUCA.
GeneTreeiENSGT00390000000970.
HOGENOMiHOG000007534.
HOVERGENiHBG012424.
InParanoidiQ3SZ87.
KOiK13251.
OMAiKHKIAVK.
OrthoDBiEOG7W9RWF.
TreeFamiTF314998.

Family and domain databases

InterProiIPR009779. SSR3.
[Graphical view]
PANTHERiPTHR13399. PTHR13399. 1 hit.
PfamiPF07074. TRAP-gamma. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3SZ87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPKGGPKQQ SEEDLLLQDF SRNLSAKSSA LFFGNAFIVS AIPIWLYWRI
60 70 80 90 100
WHMDLIQSAV LYSVMTLVST YLVAFAYKNV KFVLKHKVAQ KREDAVSKEV
110 120 130 140 150
TRKLSEADNR KMSRKEKDER ILWKKNEVAD YEATTFSIFY NNTLFLVLVI
160 170 180
VASFFILKNF NPTVNYILSI SASSGLIALL STGSK
Length:185
Mass (Da):21,075
Last modified:October 11, 2005 - v1
Checksum:iD8E3A40FEF18A3DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103053 mRNA. Translation: AAI03054.1.
RefSeqiNP_001070512.1. NM_001077044.2.
UniGeneiBt.49088.

Genome annotation databases

EnsembliENSBTAT00000024583; ENSBTAP00000024583; ENSBTAG00000018471.
GeneIDi767980.
KEGGibta:767980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103053 mRNA. Translation: AAI03054.1.
RefSeqiNP_001070512.1. NM_001077044.2.
UniGeneiBt.49088.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000024583.

Proteomic databases

PaxDbiQ3SZ87.
PeptideAtlasiQ3SZ87.
PRIDEiQ3SZ87.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000024583; ENSBTAP00000024583; ENSBTAG00000018471.
GeneIDi767980.
KEGGibta:767980.

Organism-specific databases

CTDi6747.

Phylogenomic databases

eggNOGiKOG4490. Eukaryota.
ENOG410XR1X. LUCA.
GeneTreeiENSGT00390000000970.
HOGENOMiHOG000007534.
HOVERGENiHBG012424.
InParanoidiQ3SZ87.
KOiK13251.
OMAiKHKIAVK.
OrthoDBiEOG7W9RWF.
TreeFamiTF314998.

Family and domain databases

InterProiIPR009779. SSR3.
[Graphical view]
PANTHERiPTHR13399. PTHR13399. 1 hit.
PfamiPF07074. TRAP-gamma. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Heart ventricle.

Entry informationi

Entry nameiSSRG_BOVIN
AccessioniPrimary (citable) accession number: Q3SZ87
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: October 11, 2005
Last modified: July 6, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.