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Protein

Ribonuclease P protein subunit p30

Gene

RPP30

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p30 (EC:3.1.26.5)
Short name:
RNaseP protein p30
Alternative name(s):
RNase P subunit 2
Gene namesi
Name:RPP30
Synonyms:RNASEP2
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136 Componenti: Unplaced

Subcellular locationi

Nucleusnucleolus By similarity

GO - Cellular componenti

  1. nucleolus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 268267Ribonuclease P protein subunit p30PRO_0000236681Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineBy similarity
Modified residuei251 – 2511PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PRIDEiQ3SZ21.

Interactioni

Subunit structurei

RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000003871.

Structurei

3D structure databases

ProteinModelPortaliQ3SZ21.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1603.
HOGENOMiHOG000157793.
HOVERGENiHBG010226.
InParanoidiQ3SZ21.
KOiK03539.

Family and domain databases

InterProiIPR016195. Pol/histidinol_Pase-like.
IPR002738. RNase_P_p30.
[Graphical view]
PANTHERiPTHR13031. PTHR13031. 1 hit.
PfamiPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMiSSF89550. SSF89550. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3SZ21-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVFADLDLR AGSDLKALRG LVENAAHLGY SVVAINHVVE FKEKKQEIEK
60 70 80 90 100
PVAVSELFTT LPIVQGKSKP IKILTRLTII VSDPSHCNVL RATSSRVRLY
110 120 130 140 150
DIVAVFPKTE KLFHVACTHL DVDLVCITVT EKLPFYFKRP PINVAIDRGV
160 170 180 190 200
GFELLYSPAI KDSTMRRYTI SNALNLMQVC KGKNVIISSA AERPLEIRGP
210 220 230 240 250
YDVANLGLLF GLSESDAKAA VSTNCRAVLL HGETRKTAFG IISTVKKPRT
260
SEADDDSLPA CKKAKCES
Length:268
Mass (Da):29,395
Last modified:October 11, 2005 - v1
Checksum:iD61883E7AFAFED73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103240 mRNA. Translation: AAI03241.1.
RefSeqiNP_001030538.1. NM_001035461.1.
UniGeneiBt.48969.

Genome annotation databases

GeneIDi615098.
KEGGibta:615098.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103240 mRNA. Translation: AAI03241.1.
RefSeqiNP_001030538.1. NM_001035461.1.
UniGeneiBt.48969.

3D structure databases

ProteinModelPortaliQ3SZ21.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000003871.

Proteomic databases

PRIDEiQ3SZ21.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi615098.
KEGGibta:615098.

Organism-specific databases

CTDi10556.

Phylogenomic databases

eggNOGiCOG1603.
HOGENOMiHOG000157793.
HOVERGENiHBG010226.
InParanoidiQ3SZ21.
KOiK03539.

Miscellaneous databases

NextBioi20899443.

Family and domain databases

InterProiIPR016195. Pol/histidinol_Pase-like.
IPR002738. RNase_P_p30.
[Graphical view]
PANTHERiPTHR13031. PTHR13031. 1 hit.
PfamiPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMiSSF89550. SSF89550. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Thymus.

Entry informationi

Entry nameiRPP30_BOVIN
AccessioniPrimary (citable) accession number: Q3SZ21
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: October 11, 2005
Last modified: March 4, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.