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Protein

Xylulose kinase

Gene

XYLB

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.By similarity

Catalytic activityi

ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei99SubstrateBy similarity1
Binding sitei170SubstrateBy similarity1
Binding sitei280SubstrateBy similarity1
Binding sitei281SubstrateBy similarity1
Binding sitei355ATPBy similarity1
Binding sitei445ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi441 – 442ATPBy similarity2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-13243
ReactomeiR-BTA-5661270 Catabolism of glucuronate to xylulose-5-phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Xylulose kinase (EC:2.7.1.17)
Short name:
Xylulokinase
Gene namesi
Name:XYLB
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 22

Organism-specific databases

VGNCiVGNC:37011 XYLB

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002309841 – 490Xylulose kinaseAdd BLAST490

Proteomic databases

PaxDbiQ3SYZ6
PeptideAtlasiQ3SYZ6
PRIDEiQ3SYZ6

Expressioni

Gene expression databases

BgeeiENSBTAG00000011278

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000030820

Structurei

3D structure databases

ProteinModelPortaliQ3SYZ6
SMRiQ3SYZ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FGGY kinase family.Curated

Phylogenomic databases

eggNOGiKOG2531 Eukaryota
COG1070 LUCA
GeneTreeiENSGT00390000010821
HOGENOMiHOG000174850
HOVERGENiHBG053124
InParanoidiQ3SYZ6
KOiK00854
OMAiMWVQALD
OrthoDBiEOG091G07Q3
TreeFamiTF313643

Family and domain databases

InterProiView protein in InterPro
IPR000577 Carb_kinase_FGGY
IPR018485 Carb_kinase_FGGY_C
IPR018484 Carb_kinase_FGGY_N
PfamiView protein in Pfam
PF02782 FGGY_C, 1 hit
PF00370 FGGY_N, 1 hit
PIRSFiPIRSF000538 GlpK, 1 hit

Sequencei

Sequence statusi: Complete.

Q3SYZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAERAARHCC LGWDFSTQQV KVVAVDAELS VFYEDSVHFD RDLVEFGTQG
60 70 80 90 100
GVHVHKDGLT VTSPVLMWVQ ALDIILEKMK ASGFDFSQVL ALSGAGQQHG
110 120 130 140 150
SVYWKTGASQ VLTSLSPDLP LREQLQACFS ISNCPVWMDS STAAQCRQLE
160 170 180 190 200
AAVGGAQALS LLTGSRAYER FTGNQIAKIY QQNPEAYSHT ERISLVSSFA
210 220 230 240 250
ASLFLGSYSP VDYSDGSGMN LLQIQDKVWS QACLGACAPR LEEKLGRPVP
260 270 280 290 300
SCSIVGAISS YFVQRYGFPP ECKVVAFTGD NPASLAGMRL EEGDIAVSLG
310 320 330 340 350
TSDTLFLWLQ EPTPALEGHI FCNPVDPQHY MALLCFKNGS LMREKIRDES
360 370 380 390 400
ASGSWSKFSK ALQSTGMGNS GNLGFYFDVM EITPEIIGRH RFTAENHEVS
410 420 430 440 450
AFPQDVEIRA LIEGQFMAKK IHAEALGYRV MPKTKILATG GASHNRDILQ
460 470 480 490
VLADVFGAPV YVIDTANSAC VGSAYRAFHG PSLLCLVSIY
Length:490
Mass (Da):53,305
Last modified:October 11, 2005 - v1
Checksum:iC681FED9E37A01F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103316 mRNA Translation: AAI03317.1
RefSeqiNP_001029655.1, NM_001034483.1
UniGeneiBt.17735

Genome annotation databases

EnsembliENSBTAT00000030851; ENSBTAP00000030820; ENSBTAG00000011278
GeneIDi515146
KEGGibta:515146

Similar proteinsi

Entry informationi

Entry nameiXYLB_BOVIN
AccessioniPrimary (citable) accession number: Q3SYZ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: October 11, 2005
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome