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Q3SYZ6

- XYLB_BOVIN

UniProt

Q3SYZ6 - XYLB_BOVIN

Protein

Xylulose kinase

Gene

XYLB

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.By similarity

    Catalytic activityi

    ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei99 – 991SubstrateBy similarity
    Binding sitei170 – 1701SubstrateBy similarity
    Binding sitei280 – 2801SubstrateBy similarity
    Binding sitei281 – 2811SubstrateBy similarity
    Binding sitei355 – 3551ATPBy similarity
    Binding sitei445 – 4451ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi441 – 4422ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. xylulokinase activity Source: UniProtKB

    GO - Biological processi

    1. carbohydrate phosphorylation Source: GOC
    2. D-xylose metabolic process Source: UniProtKB-KW
    3. xylulose metabolic process Source: UniProtKB

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Carbohydrate metabolism, Xylose metabolism

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-13243.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xylulose kinase (EC:2.7.1.17)
    Short name:
    Xylulokinase
    Gene namesi
    Name:XYLB
    OrganismiBos taurus (Bovine)
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 22

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 490490Xylulose kinasePRO_0000230984Add
    BLAST

    Proteomic databases

    PRIDEiQ3SYZ6.

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Protein-protein interaction databases

    STRINGi9913.ENSBTAP00000030820.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3SYZ6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the FGGY kinase family.Curated

    Phylogenomic databases

    eggNOGiCOG1070.
    GeneTreeiENSGT00390000010821.
    HOGENOMiHOG000174850.
    HOVERGENiHBG053124.
    InParanoidiQ3SYZ6.
    KOiK00854.
    OMAiGSYSPID.
    OrthoDBiEOG751NFS.
    TreeFamiTF313643.

    Family and domain databases

    InterProiIPR018485. Carb_kinase_FGGY_C.
    IPR018484. Carb_kinase_FGGY_N.
    [Graphical view]
    PfamiPF02782. FGGY_C. 1 hit.
    PF00370. FGGY_N. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3SYZ6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAERAARHCC LGWDFSTQQV KVVAVDAELS VFYEDSVHFD RDLVEFGTQG    50
    GVHVHKDGLT VTSPVLMWVQ ALDIILEKMK ASGFDFSQVL ALSGAGQQHG 100
    SVYWKTGASQ VLTSLSPDLP LREQLQACFS ISNCPVWMDS STAAQCRQLE 150
    AAVGGAQALS LLTGSRAYER FTGNQIAKIY QQNPEAYSHT ERISLVSSFA 200
    ASLFLGSYSP VDYSDGSGMN LLQIQDKVWS QACLGACAPR LEEKLGRPVP 250
    SCSIVGAISS YFVQRYGFPP ECKVVAFTGD NPASLAGMRL EEGDIAVSLG 300
    TSDTLFLWLQ EPTPALEGHI FCNPVDPQHY MALLCFKNGS LMREKIRDES 350
    ASGSWSKFSK ALQSTGMGNS GNLGFYFDVM EITPEIIGRH RFTAENHEVS 400
    AFPQDVEIRA LIEGQFMAKK IHAEALGYRV MPKTKILATG GASHNRDILQ 450
    VLADVFGAPV YVIDTANSAC VGSAYRAFHG PSLLCLVSIY 490
    Length:490
    Mass (Da):53,305
    Last modified:October 11, 2005 - v1
    Checksum:iC681FED9E37A01F3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC103316 mRNA. Translation: AAI03317.1.
    RefSeqiNP_001029655.1. NM_001034483.1.
    UniGeneiBt.17735.

    Genome annotation databases

    EnsembliENSBTAT00000030851; ENSBTAP00000030820; ENSBTAG00000011278.
    GeneIDi515146.
    KEGGibta:515146.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC103316 mRNA. Translation: AAI03317.1 .
    RefSeqi NP_001029655.1. NM_001034483.1.
    UniGenei Bt.17735.

    3D structure databases

    ProteinModelPortali Q3SYZ6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9913.ENSBTAP00000030820.

    Proteomic databases

    PRIDEi Q3SYZ6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000030851 ; ENSBTAP00000030820 ; ENSBTAG00000011278 .
    GeneIDi 515146.
    KEGGi bta:515146.

    Organism-specific databases

    CTDi 9942.

    Phylogenomic databases

    eggNOGi COG1070.
    GeneTreei ENSGT00390000010821.
    HOGENOMi HOG000174850.
    HOVERGENi HBG053124.
    InParanoidi Q3SYZ6.
    KOi K00854.
    OMAi GSYSPID.
    OrthoDBi EOG751NFS.
    TreeFami TF313643.

    Enzyme and pathway databases

    BioCyci MetaCyc:MONOMER-13243.

    Miscellaneous databases

    NextBioi 20871683.

    Family and domain databases

    InterProi IPR018485. Carb_kinase_FGGY_C.
    IPR018484. Carb_kinase_FGGY_N.
    [Graphical view ]
    Pfami PF02782. FGGY_C. 1 hit.
    PF00370. FGGY_N. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Mammalian Gene Collection (MGC) project
      Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Hereford.
      Tissue: Uterus.

    Entry informationi

    Entry nameiXYLB_BOVIN
    AccessioniPrimary (citable) accession number: Q3SYZ6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3