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Protein

F-box only protein 15

Gene

FBXO15

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.By similarity

Keywords - Biological processi

Ubl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
F-box only protein 15
Gene namesi
Name:FBXO15
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 24

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 466466F-box only protein 15PRO_0000235794Add
BLAST

Proteomic databases

PaxDbiQ3SYW0.
PRIDEiQ3SYW0.

Interactioni

Subunit structurei

Directly interacts with SKP1 and CUL1.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000012776.

Structurei

3D structure databases

ProteinModelPortaliQ3SYW0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini27 – 7347F-boxPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 F-box domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IERD. Eukaryota.
ENOG410YHRX. LUCA.
GeneTreeiENSGT00390000017498.
HOGENOMiHOG000247014.
HOVERGENiHBG051566.
InParanoidiQ3SYW0.
KOiK10298.
OMAiYHLANDN.
OrthoDBiEOG7V4B18.
TreeFamiTF332483.

Family and domain databases

InterProiIPR001810. F-box_dom.
[Graphical view]
PfamiPF12937. F-box-like. 1 hit.
[Graphical view]
SMARTiSM00256. FBOX. 1 hit.
[Graphical view]
SUPFAMiSSF81383. SSF81383. 1 hit.
PROSITEiPS50181. FBOX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3SYW0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPAGPAALS RRARQDKVCR RPSTGCSASL DSLPSEVLLK ILSYLDAAAL
60 70 80 90 100
LCAGCVNRRF YHLANDNFIW IRIYSTAFSP RRSHWRVDPA EKTDLSVNLL
110 120 130 140 150
SAGDKEAGYW KKEYLTKQIA SVKAALARVL KPLHPHTGLP VKTKEALRVS
160 170 180 190 200
GLGWVIILRA ADGREYTMEH ADLSVNDSSV TVVWYGKDWP PLATLSTLDL
210 220 230 240 250
CGATPVFMGQ SRTPSRIRPR WHSLITKYQL SQLTESSAVG GDRLMRVFCL
260 270 280 290 300
PPGLVVGLWK REEELAFVMA NLHLHCLVER SMLGSPAVPY ELPPHTPVSD
310 320 330 340 350
DSPERGLHGY RLHVDMHSGG ASCLCGSFHN LSASKGYLEN EYMKLTVISF
360 370 380 390 400
KNNTEHLPLI GKVGLSWKTN SFDGCIKSCS IMDLTLLEEY GKPFWCFSSP
410 420 430 440 450
VCVRCCPGPS DGPSFLGEAY CVDYSDSEGR LHMELVWVEE TEEYFIVSLA
460
LYLRLAKVNQ WFGTQY
Length:466
Mass (Da):51,967
Last modified:October 11, 2005 - v1
Checksum:i6B7C4052FF0EDFF7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103359 mRNA. Translation: AAI03360.1.
RefSeqiNP_001030193.1. NM_001035021.1.
UniGeneiBt.13624.

Genome annotation databases

EnsembliENSBTAT00000012776; ENSBTAP00000012776; ENSBTAG00000009686.
GeneIDi505376.
KEGGibta:505376.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103359 mRNA. Translation: AAI03360.1.
RefSeqiNP_001030193.1. NM_001035021.1.
UniGeneiBt.13624.

3D structure databases

ProteinModelPortaliQ3SYW0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000012776.

Proteomic databases

PaxDbiQ3SYW0.
PRIDEiQ3SYW0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000012776; ENSBTAP00000012776; ENSBTAG00000009686.
GeneIDi505376.
KEGGibta:505376.

Organism-specific databases

CTDi201456.

Phylogenomic databases

eggNOGiENOG410IERD. Eukaryota.
ENOG410YHRX. LUCA.
GeneTreeiENSGT00390000017498.
HOGENOMiHOG000247014.
HOVERGENiHBG051566.
InParanoidiQ3SYW0.
KOiK10298.
OMAiYHLANDN.
OrthoDBiEOG7V4B18.
TreeFamiTF332483.

Miscellaneous databases

NextBioi20867115.

Family and domain databases

InterProiIPR001810. F-box_dom.
[Graphical view]
PfamiPF12937. F-box-like. 1 hit.
[Graphical view]
SMARTiSM00256. FBOX. 1 hit.
[Graphical view]
SUPFAMiSSF81383. SSF81383. 1 hit.
PROSITEiPS50181. FBOX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus.
    Tissue: Ileum.

Entry informationi

Entry nameiFBX15_BOVIN
AccessioniPrimary (citable) accession number: Q3SYW0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: October 11, 2005
Last modified: May 11, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.