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Protein

F-box only protein 15

Gene

FBXO15

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.By similarity

GO - Biological processi

Keywordsi

Biological processUbl conjugation pathway

Enzyme and pathway databases

ReactomeiR-BTA-8951664 Neddylation
R-BTA-983168 Antigen processing: Ubiquitination & Proteasome degradation

Names & Taxonomyi

Protein namesi
Recommended name:
F-box only protein 15
Gene namesi
Name:FBXO15
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 24

Organism-specific databases

VGNCiVGNC:28893 FBXO15

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002357941 – 466F-box only protein 15Add BLAST466

Proteomic databases

PaxDbiQ3SYW0
PRIDEiQ3SYW0

Expressioni

Gene expression databases

BgeeiENSBTAG00000009686

Interactioni

Subunit structurei

Directly interacts with SKP1 and CUL1.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000012776

Structurei

3D structure databases

ProteinModelPortaliQ3SYW0
SMRiQ3SYW0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 73F-boxPROSITE-ProRule annotationAdd BLAST47

Phylogenomic databases

eggNOGiENOG410IERD Eukaryota
ENOG410YHRX LUCA
GeneTreeiENSGT00390000017498
HOGENOMiHOG000247014
HOVERGENiHBG051566
InParanoidiQ3SYW0
KOiK10298
OMAiYWKKEYI
OrthoDBiEOG091G0ISW
TreeFamiTF332483

Family and domain databases

InterProiView protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
PfamiView protein in Pfam
PF12937 F-box-like, 1 hit
SMARTiView protein in SMART
SM00256 FBOX, 1 hit
SUPFAMiSSF81383 SSF81383, 1 hit
PROSITEiView protein in PROSITE
PS50181 FBOX, 1 hit

Sequencei

Sequence statusi: Complete.

Q3SYW0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPAGPAALS RRARQDKVCR RPSTGCSASL DSLPSEVLLK ILSYLDAAAL
60 70 80 90 100
LCAGCVNRRF YHLANDNFIW IRIYSTAFSP RRSHWRVDPA EKTDLSVNLL
110 120 130 140 150
SAGDKEAGYW KKEYLTKQIA SVKAALARVL KPLHPHTGLP VKTKEALRVS
160 170 180 190 200
GLGWVIILRA ADGREYTMEH ADLSVNDSSV TVVWYGKDWP PLATLSTLDL
210 220 230 240 250
CGATPVFMGQ SRTPSRIRPR WHSLITKYQL SQLTESSAVG GDRLMRVFCL
260 270 280 290 300
PPGLVVGLWK REEELAFVMA NLHLHCLVER SMLGSPAVPY ELPPHTPVSD
310 320 330 340 350
DSPERGLHGY RLHVDMHSGG ASCLCGSFHN LSASKGYLEN EYMKLTVISF
360 370 380 390 400
KNNTEHLPLI GKVGLSWKTN SFDGCIKSCS IMDLTLLEEY GKPFWCFSSP
410 420 430 440 450
VCVRCCPGPS DGPSFLGEAY CVDYSDSEGR LHMELVWVEE TEEYFIVSLA
460
LYLRLAKVNQ WFGTQY
Length:466
Mass (Da):51,967
Last modified:October 11, 2005 - v1
Checksum:i6B7C4052FF0EDFF7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103359 mRNA Translation: AAI03360.1
RefSeqiNP_001030193.1, NM_001035021.1
UniGeneiBt.13624

Genome annotation databases

EnsembliENSBTAT00000012776; ENSBTAP00000012776; ENSBTAG00000009686
GeneIDi505376
KEGGibta:505376

Similar proteinsi

Entry informationi

Entry nameiFBX15_BOVIN
AccessioniPrimary (citable) accession number: Q3SYW0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: October 11, 2005
Last modified: March 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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