Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q3SY00

- T10IP_HUMAN

UniProt

Q3SY00 - T10IP_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Testis-specific protein 10-interacting protein

Gene

TSGA10IP

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-specific protein 10-interacting protein
Alternative name(s):
Tsga10-interacting protein
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:26555. TSGA10IP.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134983361.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 556556Testis-specific protein 10-interacting proteinPRO_0000331421Add
BLAST

Proteomic databases

MaxQBiQ3SY00.
PRIDEiQ3SY00.

PTM databases

PhosphoSiteiQ3SY00.

Expressioni

Gene expression databases

CleanExiHS_TSGA10IP.
GenevestigatoriQ3SY00.

Interactioni

Protein-protein interaction databases

BioGridi129021. 10 interactions.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili379 – 46486Sequence AnalysisAdd
BLAST

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG28878.
GeneTreeiENSGT00390000008351.
HOGENOMiHOG000170724.
HOVERGENiHBG096788.
InParanoidiQ3SY00.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q3SY00-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGQDTDMLNT YQQLVRTPSV RPGQDVRLQA PGTRTGLLKL LSTVSQDKQG
60 70 80 90 100
CLGSGDGVPN QDLQQRSQSS RQTAKKDRKP RGQSKKGQGS EESEDHFPLL
110 120 130 140 150
PRKPSFPFQW AWESIATDVR AVLQPSSPTP GHQALPMPSS FSQRQSRRKS
160 170 180 190 200
TANLPEAHGC CWKTEAQNLK ARQQLGAWGG VSIPTGKGEL GSEPPSGLQL
210 220 230 240 250
PGRRPGSGSA SDKQVQLQSL GAEEAERGLS SGVLPQRPRR GSISEEEQFS
260 270 280 290 300
EATEEAEEGE HRTPCRRRAG CQRKGQISGE EASDEGEVQG QSQGSSPSFN
310 320 330 340 350
NLRRRQWRKT RAKELQGPWD LEKLHRQLQR DLDCGPQKLP WKTLRAAFQA
360 370 380 390 400
SKRNGKAYAS GYDETFVSAN LPNRTFHKRQ EATRSLLQAW ERQRQEERQQ
410 420 430 440 450
AELRRARTQH VQRQVAHCLA AYAPRGSRGP GAAQRKLEEL RRQERQRFAE
460 470 480 490 500
YQAELQGIQH RVQARPFLFQ QAMQANARLT VTRRFSQVLS ALGLDEEQLL
510 520 530 540 550
SEAGKVDREG TPRKPRSHRS MGVRMEHSPQ RPPRTEPTGS QPDRHYNPSL

DPECSP
Length:556
Mass (Da):62,381
Last modified:July 9, 2014 - v2
Checksum:iA676754C093FDA61
GO
Isoform 2 (identifier: Q3SY00-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     336-404: PQKLPWKTLR...QEERQQAELR → SHQEPAAGLG...AEAPGATALC
     405-556: Missing.

Note: No experimental confirmation available.

Show »
Length:403
Mass (Da):42,887
Checksum:i33CEDFE052DA823A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti67 – 671S → P in BAB71488. (PubMed:14702039)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti210 – 2101A → V.
Corresponds to variant rs565921 [ dbSNP | Ensembl ].
VAR_042855
Natural varianti237 – 2371R → S.
Corresponds to variant rs7927388 [ dbSNP | Ensembl ].
VAR_042856
Natural varianti292 – 2921S → N.
Corresponds to variant rs7927826 [ dbSNP | Ensembl ].
VAR_042857
Natural varianti305 – 3051R → P.
Corresponds to variant rs7927841 [ dbSNP | Ensembl ].
VAR_042858
Natural varianti521 – 5211M → V.1 Publication
Corresponds to variant rs491973 [ dbSNP | Ensembl ].
VAR_042859

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei336 – 40469PQKLP…QAELR → SHQEPAAGLGAAAAGGAAAG RAAAGPDTACTAAGGPLPGS LRTQREPGPWGGPAQAGGAE APGATALC in isoform 2. 1 PublicationVSP_033196Add
BLAST
Alternative sequencei405 – 556152Missing in isoform 2. 1 PublicationVSP_033197Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK057442 mRNA. Translation: BAB71488.1.
AP006287 Genomic DNA. No translation available.
BC104022 mRNA. Translation: AAI04023.1.
BC104023 mRNA. Translation: AAI04024.1.
CCDSiCCDS66138.1. [Q3SY00-1]
RefSeqiNP_689975.2. NM_152762.2. [Q3SY00-1]
UniGeneiHs.350671.

Genome annotation databases

EnsembliENST00000532620; ENSP00000484252; ENSG00000175513. [Q3SY00-1]
ENST00000608857; ENSP00000477317; ENSG00000175513. [Q3SY00-2]
GeneIDi254187.
KEGGihsa:254187.
UCSCiuc001ogk.1. human. [Q3SY00-1]

Polymorphism databases

DMDMi121942943.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK057442 mRNA. Translation: BAB71488.1 .
AP006287 Genomic DNA. No translation available.
BC104022 mRNA. Translation: AAI04023.1 .
BC104023 mRNA. Translation: AAI04024.1 .
CCDSi CCDS66138.1. [Q3SY00-1 ]
RefSeqi NP_689975.2. NM_152762.2. [Q3SY00-1 ]
UniGenei Hs.350671.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 129021. 10 interactions.

PTM databases

PhosphoSitei Q3SY00.

Polymorphism databases

DMDMi 121942943.

Proteomic databases

MaxQBi Q3SY00.
PRIDEi Q3SY00.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000532620 ; ENSP00000484252 ; ENSG00000175513 . [Q3SY00-1 ]
ENST00000608857 ; ENSP00000477317 ; ENSG00000175513 . [Q3SY00-2 ]
GeneIDi 254187.
KEGGi hsa:254187.
UCSCi uc001ogk.1. human. [Q3SY00-1 ]

Organism-specific databases

CTDi 254187.
GeneCardsi GC11P065713.
HGNCi HGNC:26555. TSGA10IP.
neXtProti NX_Q3SY00.
PharmGKBi PA134983361.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG28878.
GeneTreei ENSGT00390000008351.
HOGENOMi HOG000170724.
HOVERGENi HBG096788.
InParanoidi Q3SY00.

Miscellaneous databases

GenomeRNAii 254187.
NextBioi 92283.
PROi Q3SY00.

Gene expression databases

CleanExi HS_TSGA10IP.
Genevestigatori Q3SY00.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Testis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT VAL-521.

Entry informationi

Entry nameiT10IP_HUMAN
AccessioniPrimary (citable) accession number: Q3SY00
Secondary accession number(s): Q3SXZ9, Q3SY01, Q96M26
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: July 9, 2014
Last modified: October 29, 2014
This is version 59 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

External Data

Dasty 3