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Protein

Uncharacterized protein KIAA1644

Gene

KIAA1644

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein KIAA1644
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

HGNCiHGNC:29335. KIAA1644.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini26 – 97ExtracellularSequence analysisAdd BLAST72
Transmembranei98 – 118HelicalSequence analysisAdd BLAST21
Topological domaini119 – 199CytoplasmicSequence analysisAdd BLAST81

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi85352.
OpenTargetsiENSG00000138944.
PharmGKBiPA164721896.

Polymorphism and mutation databases

BioMutaiKIAA1644.
DMDMi172044643.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000031895126 – 199Uncharacterized protein KIAA1644Add BLAST174

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi53N-linked (GlcNAc...)Sequence analysis1
Glycosylationi95N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ3SXP7.
PRIDEiQ3SXP7.

Expressioni

Gene expression databases

BgeeiENSG00000138944.
GenevisibleiQ3SXP7. HS.

Organism-specific databases

HPAiHPA051178.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000370568.

Structurei

3D structure databases

ProteinModelPortaliQ3SXP7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IJIJ. Eukaryota.
ENOG410Y76U. LUCA.
GeneTreeiENSGT00390000006791.
HOGENOMiHOG000170254.
HOVERGENiHBG108041.
InParanoidiQ3SXP7.
OMAiHYRVCEP.
OrthoDBiEOG091G0NP0.
PhylomeDBiQ3SXP7.
TreeFamiTF331539.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3SXP7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSCGQQSLN VLAVLFSLLF SAVLSAHFRV CEPYTDHKGR YHFGFHCPRL
60 70 80 90 100
SDNKTFILCC HHNNTVFKYC CNETEFQAVM QANLTASSEG YMHNNYTALL
110 120 130 140 150
GVWIYGFFVL MLLVLDLLYY SAMNYDICKV YLARWGIQGR WMKQDPRRWG
160 170 180 190
NPARAPRPGQ RAPQPQPPPG PLPQAPQAVH TLRGDAHSPP LMTFQSSSA
Length:199
Mass (Da):22,573
Last modified:February 26, 2008 - v2
Checksum:i55C8E5B55D3B60F6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti197S → L in AAI04185 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL022339, AL591914 Genomic DNA. Translation: CAI41964.2.
AL591914, AL022339 Genomic DNA. Translation: CAM28349.1.
BC104183 mRNA. Translation: AAI04184.1.
BC104184 mRNA. Translation: AAI04185.1.
AB051431 mRNA. Translation: BAB33314.1.
CCDSiCCDS43025.1.
RefSeqiNP_001092764.1. NM_001099294.1.
XP_005261847.1. XM_005261790.3.
UniGeneiHs.6829.

Genome annotation databases

EnsembliENST00000381176; ENSP00000370568; ENSG00000138944.
GeneIDi85352.
KEGGihsa:85352.
UCSCiuc003bet.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL022339, AL591914 Genomic DNA. Translation: CAI41964.2.
AL591914, AL022339 Genomic DNA. Translation: CAM28349.1.
BC104183 mRNA. Translation: AAI04184.1.
BC104184 mRNA. Translation: AAI04185.1.
AB051431 mRNA. Translation: BAB33314.1.
CCDSiCCDS43025.1.
RefSeqiNP_001092764.1. NM_001099294.1.
XP_005261847.1. XM_005261790.3.
UniGeneiHs.6829.

3D structure databases

ProteinModelPortaliQ3SXP7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000370568.

Polymorphism and mutation databases

BioMutaiKIAA1644.
DMDMi172044643.

Proteomic databases

PaxDbiQ3SXP7.
PRIDEiQ3SXP7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000381176; ENSP00000370568; ENSG00000138944.
GeneIDi85352.
KEGGihsa:85352.
UCSCiuc003bet.3. human.

Organism-specific databases

CTDi85352.
DisGeNETi85352.
GeneCardsiKIAA1644.
HGNCiHGNC:29335. KIAA1644.
HPAiHPA051178.
neXtProtiNX_Q3SXP7.
OpenTargetsiENSG00000138944.
PharmGKBiPA164721896.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IJIJ. Eukaryota.
ENOG410Y76U. LUCA.
GeneTreeiENSGT00390000006791.
HOGENOMiHOG000170254.
HOVERGENiHBG108041.
InParanoidiQ3SXP7.
OMAiHYRVCEP.
OrthoDBiEOG091G0NP0.
PhylomeDBiQ3SXP7.
TreeFamiTF331539.

Miscellaneous databases

GenomeRNAii85352.
PROiQ3SXP7.

Gene expression databases

BgeeiENSG00000138944.
GenevisibleiQ3SXP7. HS.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiK1644_HUMAN
AccessioniPrimary (citable) accession number: Q3SXP7
Secondary accession number(s): A6NHP0
, A9Z1Z0, Q3SXP8, Q5JZ71, Q9BYB5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: November 2, 2016
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.