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Protein

Protein shisa-like-1

Gene

SHISAL1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein shisa-like-1Imported
Gene namesi
Name:SHISAL1Imported
Synonyms:KIAA1644
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000138944.7
HGNCiHGNC:29335 SHISAL1
neXtProtiNX_Q3SXP7

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini26 – 97ExtracellularSequence analysisAdd BLAST72
Transmembranei98 – 118HelicalSequence analysisAdd BLAST21
Topological domaini119 – 199CytoplasmicSequence analysisAdd BLAST81

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi85352
OpenTargetsiENSG00000138944
PharmGKBiPA164721896

Polymorphism and mutation databases

BioMutaiKIAA1644
DMDMi172044643

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000031895126 – 199Protein shisa-like-1Add BLAST174

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi53N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi95N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ3SXP7
PRIDEiQ3SXP7
ProteomicsDBi61819

Expressioni

Gene expression databases

BgeeiENSG00000138944
GenevisibleiQ3SXP7 HS

Organism-specific databases

HPAiHPA051178

Interactioni

Protein-protein interaction databases

BioGridi124484, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ3SXP7
SMRiQ3SXP7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the shisa family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IJIJ Eukaryota
ENOG410Y76U LUCA
GeneTreeiENSGT00390000006791
HOGENOMiHOG000170254
HOVERGENiHBG108041
InParanoidiQ3SXP7
OMAiHYRVCEP
OrthoDBiEOG091G0NP0
PhylomeDBiQ3SXP7
TreeFamiTF331539

Family and domain databases

InterProiView protein in InterPro
IPR026910 Shisa
PANTHERiPTHR31395 PTHR31395, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3SXP7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSCGQQSLN VLAVLFSLLF SAVLSAHFRV CEPYTDHKGR YHFGFHCPRL
60 70 80 90 100
SDNKTFILCC HHNNTVFKYC CNETEFQAVM QANLTASSEG YMHNNYTALL
110 120 130 140 150
GVWIYGFFVL MLLVLDLLYY SAMNYDICKV YLARWGIQGR WMKQDPRRWG
160 170 180 190
NPARAPRPGQ RAPQPQPPPG PLPQAPQAVH TLRGDAHSPP LMTFQSSSA
Length:199
Mass (Da):22,573
Last modified:February 26, 2008 - v2
Checksum:i55C8E5B55D3B60F6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti197S → L in AAI04185 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL022339 Genomic DNA No translation available.
AL591914 Genomic DNA No translation available.
BC104183 mRNA Translation: AAI04184.1
BC104184 mRNA Translation: AAI04185.1
AB051431 mRNA Translation: BAB33314.1
CCDSiCCDS43025.1
RefSeqiNP_001092764.1, NM_001099294.1
XP_005261847.1, XM_005261790.3
UniGeneiHs.6829

Genome annotation databases

EnsembliENST00000381176; ENSP00000370568; ENSG00000138944
GeneIDi85352
KEGGihsa:85352
UCSCiuc003bet.3 human

Similar proteinsi

Entry informationi

Entry nameiSHSL1_HUMAN
AccessioniPrimary (citable) accession number: Q3SXP7
Secondary accession number(s): A6NHP0
, A9Z1Z0, Q3SXP8, Q5JZ71, Q9BYB5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: June 20, 2018
This is version 80 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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