Reviewed, UniProtKB/Swiss-Prot Q3SX04 (PRCM_BOVIN)

Names and origin

Protein names	Recommended name:     Probable proline racemase     EC=5.1.1.4
Organism	Bos taurus (Bovine)
Taxonomic identifier	9913 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	354 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Catalyzes the interconversion of L- and D-proline By similarity.
Catalytic activity	L-proline = D-proline.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the proline racemase family.

Ontologies

Keywords
Molecular function	Isomerase
Gene Ontology (GO)
Molecular function	proline racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 354	354	Probable proline racemase		PRO_0000288948
Regions
	Region	105 – 106	2	Substrate binding By similarity
	Region	274 – 275	2	Substrate binding By similarity
Sites
	Active site	104	1	Proton acceptor By similarity
	Binding site	269	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3SX04-1 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 997C31A237A82510	FASTA	354	37,957
	10 20 30 40 50 60 MAGPLTVPWM PPHDPGTPAL SVVDMHTGGE PLRIVLAGCP EVVGPTLLAK RRYMRQHLDH 70 80 90 100 110 120 VRRRLMFEPR GHRDMYGAVL VPSELPDAHL GVLFLNNEGY SSMCGHAVLA LGRFALDFGL 130 140 150 160 170 180 VPAPPSDAQE ALVNIHCPCG LVAAFVECEG CRSRGPVRFH SVPAFVLATD FLVDVPGRGK 190 200 210 220 230 240 VVVDIAYGGA FYAFVSAEKL GLDVCSAKMG DLVAAASAVT EAVKAQFKIS HPDSEDLAFL 250 260 270 280 290 300 YGTILTDGKD TYNEEPTTNI CVFADEQVDR SPTGSGVTAR IALQYHKGLL ELNQTRAFKS 310 320 330 340 350 SATGSVFTGK AVREAKCGDF KAVIVEVSGQ AHYTGTASFI VEDDDPLRDG FLLK

References

[1]	NIH - Mammalian Gene Collection (MGC) project Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Hereford. Tissue: Uterus.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC104573 mRNA. Translation: AAI04574.1.
IPI	IPI00717986.
RefSeq	NP_001029558.1.
UniGene	Bt.30092
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSBTAG00000030824. Bos taurus. [Contig view]
GeneID	510525.
KEGG	bta:510525.
Phylogenomic databases
HOVERGEN	Q3SX04.
Enzyme and pathway databases
BRENDA	5.1.1.4. 251.
Family and domain databases
InterPro	IPR008794. Pro_racemase. [Graphical view]
Pfam	PF05544. Pro_racemase. 1 hit. [Graphical view]
PIRSF	PIRSF029792. Pro_racemase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PRCM_BOVIN

Accession

Primary (citable) accession number: Q3SX04

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 29, 2007
Last sequence update:	October 11, 2005
Last modified:	June 16, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)