Q3SWE0 (GLND_NITWN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	Nwi_0133

Organism

Nitrobacter winogradskyi (strain Nb-255 / ATCC 25391) [Complete proteome] [HAMAP]

Taxonomic identifier

323098 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Nitrobacter

Protein attributes

Sequence length	925 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: EC amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 925	925	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_0000231682

Sequences

	Sequence		Length	Mass (Da)
	Q3SWE0 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 9B4D8076280C0070	FASTA	925	104,377
	10 20 30 40 50 60 MVLPTTKDAT AAGAGFDTVR IIGDIDALAE KHAGHEDVFR SAVSRLLKAE LAKVRDAAQA 70 80 90 100 110 120 KLLRDRHGRH CAEWLCFVQD EIIRLSFSAA TRHLYHSPIP SDGERMAVVA TGGYGRGLMA 130 140 150 160 170 180 PESDIDLLFI LPYKQTAWGE QVAEAILYCL WDMGLNVGHA TRSVNESIRQ ARRDMTVRTG 190 200 210 220 230 240 ILEARFLTGD RALYDELISR FDTEVVQGTA AEFVAAKLAE REERHHRAGQ SRYLVEPNVK 250 260 270 280 290 300 DGKGGLRDLH TLFWIAKYVY RVRESHELLR RNVFDVREYR TFRRCADFLW SVRCNLHFAT 310 320 330 340 350 360 GRAEERLSFD LQREIAVRLG YTSHPGMQDV ERFMKHYFLT AKDVGDLTAI LCAKLEDQQA 370 380 390 400 410 420 KPAPVLSRAM SKPPGAEVRR VPDSDDFIID NNRINLAAPD LFKRDPVNLI RLFRLAQKNN 430 440 450 460 470 480 LAFHPDALRM VRRSRRLINA QLREDPESNR LFIEILTSND AETVLRRMNE TGVLGEFIRA 490 500 510 520 530 540 FGKIVSMMQF NMYHHYTVDE HLIRCIGILQ DIERGDNDEV ALAGELMRTI NPEHRPVIYI 550 560 570 580 590 600 ATLLHDVAKG RPEDHSIAGA RVARRLCPRL GFNAADTELV AWLIEQHLTM SKVAQSRDLS 610 620 630 640 650 660 DRKTIENFAA VVQSVERMKL LTILTTADIR GVGPGVWNGW KAQLLRTLYY ETEPVLTGGF 670 680 690 700 710 720 SEVNRAQRMA AAEAEFRAAF TEWSGHELNA YIARHYPAYW LKVDLEHKIR HARFLRASEQ 730 740 750 760 770 780 SGRKLNINVG FDEARGVTEL TILAADHPWL LSIIAGACAS AGANIVDAQI YTTTDGQALD 790 800 810 820 830 840 TIAISREYER DEDEGRRAAR IAEIIEQVLE GRLRLPDVMP SRAAGKRLRP FVVEPKVTIN 850 860 870 880 890 900 NQWSDRHTMI EVSGLDRPGL LFQLTTAISK LNLNIASAHV ATFGERARDV FYVTDLLGAR 910 920 ITAPTRQAAI KRALVHLLAS GNTAE

References

[1]

"Genome sequence of the chemolithoautotrophic nitrite-oxidizing bacterium Nitrobacter winogradskyi Nb-255." Starkenburg S.R., Chain P.S.G., Sayavedra-Soto L.A., Hauser L., Land M.L., Larimer F.W., Malfatti S.A., Klotz M.G., Bottomley P.J., Arp D.J., Hickey W.J. Appl. Environ. Microbiol. 72:2050-2063(2006) [PubMed: 16517654] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nb-255 / ATCC 25391.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000115 Genomic DNA. Translation: ABA03401.1.
RefSeq	YP_316753.1. NC_007406.1.
3D structure databases
ProteinModelPortal	Q3SWE0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3SWE0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3676202.
GenomeReviews	Gene locus Nwi_0133 in contig CP000115_GR.
KEGG	nwi:Nwi_0133.
NMPDR	fig|323098.3.peg.603.
PATRIC	22696587. VBINitWin102302_0149.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HBG687872.
OMA	MQHDLFH.
PhylomeDB	Q3SWE0.
ProtClustDB	PRK05092.
Enzyme and pathway databases
BioCyc	NWIN323098:NWI_0133-MONOMER.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl-transf. [Tree]
InterPro	IPR002912. ACT-bd. IPR010043. GlnD_Uridyltrans. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Gene3D	G3DSA:1.10.3210.10. HD. 1 hit.
KO	K00990.
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_NITWN

Accession

Primary (citable) accession number: Q3SWE0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	October 11, 2005
Last modified:	January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program