Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA mismatch repair protein MutS

Gene

mutS

Organism
Nitrobacter winogradskyi (strain Nb-255 / ATCC 25391)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi638 – 6458ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciNWIN323098:GJEG-501-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutSUniRule annotation
Gene namesi
Name:mutSUniRule annotation
Ordered Locus Names:Nwi_0490
OrganismiNitrobacter winogradskyi (strain Nb-255 / ATCC 25391)
Taxonomic identifieri323098 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter
Proteomesi
  • UP000002531 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 888888DNA mismatch repair protein MutSPRO_0000224385Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi323098.Nwi_0490.

Structurei

3D structure databases

ProteinModelPortaliQ3SVD4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DNA mismatch repair MutS family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D86. Bacteria.
COG0249. LUCA.
HOGENOMiHOG000221407.
KOiK03555.
OMAiCVTPMGS.
OrthoDBiEOG6Q5NPV.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00096. MutS.
InterProiIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsiTIGR01070. mutS1. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3SVD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMEQYLEIKA ANPGLLLFYR MGDFYELFFE DAEIASRALG ITLTKRGKHQ
60 70 80 90 100
GADIPMCGVP VERSDDYLHR LIAAGHRVAV CEQTEDPSAA RKRGNKSVVR
110 120 130 140 150
RDVVRLVTPG TLTEDTLLDA RANNYLLALA RARASSGVDR FALAWIDIST
160 170 180 190 200
AEFMVTECGA NELAATLARI NPNEVIVSDT LHGDPDLGAL LRELPSVTPL
210 220 230 240 250
PRDTFDGATA ERRLCDYFAV ATMDGLSAMS RLEATAAAAA VTYIDRTQIG
260 270 280 290 300
QRPPLSPPSR EASGSTMAID PATRANLELT RTLAGERRGS LLDAIDRTMT
310 320 330 340 350
AAGSRLLAQR LAAPLTDTAA ITRRLDAVAA LTADGAARDD IRAILRTAPD
360 370 380 390 400
MSRALARLSL GRGGPRDLAG LRDGVMAADQ TLARLAGLSD PPEGIAAAMQ
410 420 430 440 450
ALRGPSRELA RELGNALSEN LPLMKRDGGF VREGYDTALD EARKLRDDSR
460 470 480 490 500
LVVAAMQARY AEETGVKTLK IRHNNVLGYF VEVTAQHANR LMSAPLNATF
510 520 530 540 550
IHRQTLAGQV RFTTSELGEI EARIANAGER ALGLELDIFD RLAAMAIRNG
560 570 580 590 600
DEIRNAAHAF AQLDVAASFA KLAIDENYTR PDIDASLSFA IEGGRHPVVE
610 620 630 640 650
QALKRTGQPF IANACDLSPP PPPVEGSGES GQIWLLTGPN MAGKSTFLRQ
660 670 680 690 700
NALIALMAQV GSFVPASRAR IGIIDRLFSR VGAADDLARG RSTFMVEMVE
710 720 730 740 750
TAVILNQASE RALVILDEIG RGTATFDGLS IAWATIEHLH ESNRCRALFA
760 770 780 790 800
THYHELTALS AKLPRLFNAT VRVKEWHGEV VFLHEVLPGA ADRSYGIQVA
810 820 830 840 850
RLAGLPPSVI ARAKSVLAKL EAQDRGSTVR VLVDDLPLFA VTSRTGESAP
860 870 880
TGETSPLIEA LKSLHPDEMS PREALDALYA LKAKLPKQ
Length:888
Mass (Da):95,772
Last modified:October 11, 2005 - v1
Checksum:i3824B5221D177F8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000115 Genomic DNA. Translation: ABA03757.1.

Genome annotation databases

EnsemblBacteriaiABA03757; ABA03757; Nwi_0490.
KEGGinwi:Nwi_0490.
PATRICi22697384. VBINitWin102302_0538.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000115 Genomic DNA. Translation: ABA03757.1.

3D structure databases

ProteinModelPortaliQ3SVD4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi323098.Nwi_0490.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA03757; ABA03757; Nwi_0490.
KEGGinwi:Nwi_0490.
PATRICi22697384. VBINitWin102302_0538.

Phylogenomic databases

eggNOGiENOG4105D86. Bacteria.
COG0249. LUCA.
HOGENOMiHOG000221407.
KOiK03555.
OMAiCVTPMGS.
OrthoDBiEOG6Q5NPV.

Enzyme and pathway databases

BioCyciNWIN323098:GJEG-501-MONOMER.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00096. MutS.
InterProiIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsiTIGR01070. mutS1. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the chemolithoautotrophic nitrite-oxidizing bacterium Nitrobacter winogradskyi Nb-255."
    Starkenburg S.R., Chain P.S.G., Sayavedra-Soto L.A., Hauser L., Land M.L., Larimer F.W., Malfatti S.A., Klotz M.G., Bottomley P.J., Arp D.J., Hickey W.J.
    Appl. Environ. Microbiol. 72:2050-2063(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nb-255 / ATCC 25391.

Entry informationi

Entry nameiMUTS_NITWN
AccessioniPrimary (citable) accession number: Q3SVD4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: October 11, 2005
Last modified: December 9, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.