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Q3SRM3 (SYR_NITWN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Nwi_1807
OrganismNitrobacter winogradskyi (strain Nb-255 / ATCC 25391) [Complete proteome] [HAMAP]
Taxonomic identifier323098 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter

Protein attributes

Sequence length597 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 597597Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242055

Regions

Motif138 – 14811"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q3SRM3 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: A6DF8E91710B0424

FASTA59765,428
        10         20         30         40         50         60 
MTDSSPSQHL FADVLARVHR ACAALAEEGA LPSGLDLARI VVEPPRDASH GDMATNAAMV 

        70         80         90        100        110        120 
LAKDAKAKPR DLAERIVTKL RADDLIESAD IAGPGFINLT LKLPVWADVL RDVLRDGEGY 

       130        140        150        160        170        180 
GRSAIGAGEK VNVEYVSANP TGPMHVGHCR GAVFGDALAS LLSFAGYDVT REYYINDAGS 

       190        200        210        220        230        240 
QVDVLARSAF LRYREALGED IGEIPDGLYP GDYLKPVGQA LAAGHGDSLV KAPEAEWLGL 

       250        260        270        280        290        300 
VRAKAIGMMM EMIRGDLAAL NIRHDVFFSE RSLIDGSADR VAETIGFLRE KGDVYEGRLP 

       310        320        330        340        350        360 
PPKGAPVEDY EDREQTLFRA TAYGDDVDRP LKKSDGGYTY FASDIAYHKT KFDRGFHNMV 

       370        380        390        400        410        420 
DVWGADHGGY IKRVQAAIKA VTSGKGTLDV KIVQLVKLLR NGEPVKMSKR AGDFVTLREV 

       430        440        450        460        470        480 
VEEVGSDAVR FMMLFRKNDA VLDFDLARVI EQSKDNPVFY VQYGHARGFS IFRNAREVFP 

       490        500        510        520        530        540 
DLPEADAERR QFLGTADLER LSDPAELGLL RKLALYPRTV EAAAAAHEPH RIAFYLYDLA 

       550        560        570        580        590 
SEFHALWTKG RDLPHLRFII NNDAQITRAR LALVQGVVAV LASGLTVLGV HAPTEMR 

« Hide

References

[1]"Genome sequence of the chemolithoautotrophic nitrite-oxidizing bacterium Nitrobacter winogradskyi Nb-255."
Starkenburg S.R., Chain P.S.G., Sayavedra-Soto L.A., Hauser L., Land M.L., Larimer F.W., Malfatti S.A., Klotz M.G., Bottomley P.J., Arp D.J., Hickey W.J.
Appl. Environ. Microbiol. 72:2050-2063(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Nb-255 / ATCC 25391.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000115 Genomic DNA. Translation: ABA05068.1.
RefSeqYP_318420.1. NC_007406.1.

3D structure databases

ProteinModelPortalQ3SRM3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING323098.Nwi_1807.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA05068; ABA05068; Nwi_1807.
GeneID3677062.
KEGGnwi:Nwi_1807.
PATRIC22700414. VBINitWin102302_2028.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAPRVKGAI.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycNWIN323098:GJEG-1842-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_NITWN
AccessionPrimary (citable) accession number: Q3SRM3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 11, 2005
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries