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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Nwi_1807
OrganismiNitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)
Taxonomic identifieri323098 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter
Proteomesi
  • UP000002531 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420551 – 597Arginine--tRNA ligaseAdd BLAST597

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi323098.Nwi_1807.

Structurei

3D structure databases

ProteinModelPortaliQ3SRM3.
SMRiQ3SRM3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi138 – 148"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247214.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3SRM3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDSSPSQHL FADVLARVHR ACAALAEEGA LPSGLDLARI VVEPPRDASH
60 70 80 90 100
GDMATNAAMV LAKDAKAKPR DLAERIVTKL RADDLIESAD IAGPGFINLT
110 120 130 140 150
LKLPVWADVL RDVLRDGEGY GRSAIGAGEK VNVEYVSANP TGPMHVGHCR
160 170 180 190 200
GAVFGDALAS LLSFAGYDVT REYYINDAGS QVDVLARSAF LRYREALGED
210 220 230 240 250
IGEIPDGLYP GDYLKPVGQA LAAGHGDSLV KAPEAEWLGL VRAKAIGMMM
260 270 280 290 300
EMIRGDLAAL NIRHDVFFSE RSLIDGSADR VAETIGFLRE KGDVYEGRLP
310 320 330 340 350
PPKGAPVEDY EDREQTLFRA TAYGDDVDRP LKKSDGGYTY FASDIAYHKT
360 370 380 390 400
KFDRGFHNMV DVWGADHGGY IKRVQAAIKA VTSGKGTLDV KIVQLVKLLR
410 420 430 440 450
NGEPVKMSKR AGDFVTLREV VEEVGSDAVR FMMLFRKNDA VLDFDLARVI
460 470 480 490 500
EQSKDNPVFY VQYGHARGFS IFRNAREVFP DLPEADAERR QFLGTADLER
510 520 530 540 550
LSDPAELGLL RKLALYPRTV EAAAAAHEPH RIAFYLYDLA SEFHALWTKG
560 570 580 590
RDLPHLRFII NNDAQITRAR LALVQGVVAV LASGLTVLGV HAPTEMR
Length:597
Mass (Da):65,428
Last modified:October 11, 2005 - v1
Checksum:iA6DF8E91710B0424
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000115 Genomic DNA. Translation: ABA05068.1.
RefSeqiWP_011315064.1. NC_007406.1.

Genome annotation databases

EnsemblBacteriaiABA05068; ABA05068; Nwi_1807.
KEGGinwi:Nwi_1807.

Similar proteinsi

Entry informationi

Entry nameiSYR_NITWN
AccessioniPrimary (citable) accession number: Q3SRM3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 11, 2005
Last modified: November 22, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families