Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q3SRI5

- LPXB_NITWN

UniProt

Q3SRI5 - LPXB_NITWN

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Nitrobacter winogradskyi (strain Nb-255 / ATCC 25391)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

    Catalytic activityi

    UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    BioCyciNWIN323098:GJEG-1881-MONOMER.
    UniPathwayiUPA00359; UER00481.

    Protein family/group databases

    CAZyiGT19. Glycosyltransferase Family 19.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
    Gene namesi
    Name:lpxBUniRule annotation
    Ordered Locus Names:Nwi_1846
    OrganismiNitrobacter winogradskyi (strain Nb-255 / ATCC 25391)
    Taxonomic identifieri323098 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter
    ProteomesiUP000002531: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 396396Lipid-A-disaccharide synthasePRO_0000255202Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi323098.Nwi_1846.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3SRI5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LpxB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0763.
    HOGENOMiHOG000018004.
    KOiK00748.
    OMAiRRSEIRH.
    OrthoDBiEOG6FBWZR.

    Family and domain databases

    HAMAPiMF_00392. LpxB.
    InterProiIPR003835. Glyco_trans_19.
    [Graphical view]
    PfamiPF02684. LpxB. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00215. lpxB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q3SRI5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPDEASANPS RKIFLIATEE SGDRLGSSLM KALRRRLGCS VRFEGVGGQT    50
    MAREGLVSLF PIEELSIMGF TAVVKQLPMI VRRIRGTADA VIAAAPDVLV 100
    IIDSPDFTHR VARRVRARCR GLPIVDYVSP SVWAWRSGRA RAMRSYVDHV 150
    LALLPFEPEA YRRLGGPPCT YVGHPLLEQI GVLRPDAQER QRRDADPPTL 200
    LVLPGSRRSE IRHHLSVFGE TIGMLQQSIP EIEVVLPTTP HLVDEITPAV 250
    ATWPRRPRVV IGEDDKRAAF RVARAALAKS GTVTLELALA GVPMVAAYKA 300
    GSVEAWIARR VIRVSSVILA NLVIRENVIP EFLQEDCVPG KLAPALQEIL 350
    TDSPMRRRQL KAFDGLNTIM ATGQRSPSEL AADIVIEAMR ESRARM 396
    Length:396
    Mass (Da):43,640
    Last modified:October 11, 2005 - v1
    Checksum:iBBDE4D4CFCE7CAD7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000115 Genomic DNA. Translation: ABA05106.1.
    RefSeqiWP_011315102.1. NC_007406.1.
    YP_318458.1. NC_007406.1.

    Genome annotation databases

    EnsemblBacteriaiABA05106; ABA05106; Nwi_1846.
    GeneIDi3674817.
    KEGGinwi:Nwi_1846.
    PATRICi22700502. VBINitWin102302_2072.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000115 Genomic DNA. Translation: ABA05106.1 .
    RefSeqi WP_011315102.1. NC_007406.1.
    YP_318458.1. NC_007406.1.

    3D structure databases

    ProteinModelPortali Q3SRI5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 323098.Nwi_1846.

    Protein family/group databases

    CAZyi GT19. Glycosyltransferase Family 19.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABA05106 ; ABA05106 ; Nwi_1846 .
    GeneIDi 3674817.
    KEGGi nwi:Nwi_1846.
    PATRICi 22700502. VBINitWin102302_2072.

    Phylogenomic databases

    eggNOGi COG0763.
    HOGENOMi HOG000018004.
    KOi K00748.
    OMAi RRSEIRH.
    OrthoDBi EOG6FBWZR.

    Enzyme and pathway databases

    UniPathwayi UPA00359 ; UER00481 .
    BioCyci NWIN323098:GJEG-1881-MONOMER.

    Family and domain databases

    HAMAPi MF_00392. LpxB.
    InterProi IPR003835. Glyco_trans_19.
    [Graphical view ]
    Pfami PF02684. LpxB. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00215. lpxB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the chemolithoautotrophic nitrite-oxidizing bacterium Nitrobacter winogradskyi Nb-255."
      Starkenburg S.R., Chain P.S.G., Sayavedra-Soto L.A., Hauser L., Land M.L., Larimer F.W., Malfatti S.A., Klotz M.G., Bottomley P.J., Arp D.J., Hickey W.J.
      Appl. Environ. Microbiol. 72:2050-2063(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Nb-255 / ATCC 25391.

    Entry informationi

    Entry nameiLPXB_NITWN
    AccessioniPrimary (citable) accession number: Q3SRI5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3