Q3SQD2 (Q3SQD2_NITWN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Nwi_2255

Organism

Nitrobacter winogradskyi (strain Nb-255 / ATCC 25391) [Complete proteome] [HAMAP] EMBL ABA05509.1

Taxonomic identifier

323098 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Nitrobacter

Protein attributes

Sequence length	1175 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3SQD2 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: A2C67A5B695D6A70	FASTA	1,175	133,179
	10 20 30 40 50 60 MRPTRDTPCY AEIGIATNFS FLHGASHPQE YVHQASELRL PVIGIADRNT LAGVVRAYTE 70 80 90 100 110 120 LKNPEVRYKP RLLIGSRLVF IDGTPDILIY PRDRNAYGRL CQLLTRGKRA ATKGECHLKL 130 140 150 160 170 180 DDLLDFSEGQ LLVLALPHRL ETARAMEVLD RLRQASADGV WLAASLLYRG DDRRRLLRLQ 190 200 210 220 230 240 RIAATAHVPL LATNEVLYHH PARRPLQDVL TCVREKTAVD AIGRRLELNA ERHLKSACEM 250 260 270 280 290 300 EKLFRDLPEA IAETMRFASR IEFTLDQLQY QYPDEPVPLG KSAQRHLEDL TWAGAHKYFP 310 320 330 340 350 360 VRIPPRTRKV LHKELRLIRR LKYAHYFLTV HDIVRWARDQ DILCQGRGSA ANSAVCYVLG 370 380 390 400 410 420 VTSVDPTKVD LLFERFISRE RLEPPDIDVD FEHSRREEVM QYVYRRYGRH RAAIIATVIH 430 440 450 460 470 480 YRPRSAIRDV GKALGLTEDV TAALADTVWG SWGDEVSDAQ IRQAGFDPRN PMVRRAVALA 490 500 510 520 530 540 TELIGFPRHL SQHVGGYVLT QDRLDTYVPI GNAAMENRTF IEWDKDDVDA LRMMKVDVLA 550 560 570 580 590 600 LGMLTCIRKC FDLMAEHKGE RRELADIRSR DDDEVYQMLQ RGESLGVFQV ESRAQMNMLP 610 620 630 640 650 660 RLRPRTFYDL VIEVAIVRPG PIQGDMVHPY LKRRAMDPEK IDYPYPKNGD RNELRNVLHK 670 680 690 700 710 720 TLGVPLFQEQ AMRIAIEAAK FTSEEANGLR RAMATFRHVG TIGKFEAKMV GNMIARGYDP 730 740 750 760 770 780 VFARNCFEQI KGFGSYGFPE SHAASFAQLV YVSAWLKCFH PDAFCCGLLN SQPMGFYAPA 790 800 810 820 830 840 QIVGDARKNG VEVRPVDVSF SHSQNTLEER TGRYCAVRLG FRQIDGFKWV DKDEERGRQQ 850 860 870 880 890 900 AADKELFPPP LWGRVREGGE LQDQCLRCSP LHLSSTGGER AGSAWIGTSN PSSREQLFSS 910 920 930 940 950 960 SLTSDDWGER IVAARQHRPF ASIEDFARAT KLPKRALILL ADADAFRSLG LDRRAALWAV 970 980 990 1000 1010 1020 RRLPDDVPLP LFESAIAREL PDEHAAPLPP MPLSEQVVAD YQTVRLSLKG HPMEFLRGTL 1030 1040 1050 1060 1070 1080 SNEGVASCAE VCHANDRRRV RCAGVVLVRQ RPGSANGVVF MTLEDETGIA NIVVWPKIME 1090 1100 1110 1120 1130 1140 RYRKEVMGAR LIEVEGLIQS SPERVVHLVA SRLADRSAEL MHLANDALVS RHPLPQPAAS 1150 1160 1170 AEPFSDDRRD QPAHAAQRVR HPRNVRILPR SRDFH

References

[1]

"Genome sequence of the chemolithoautotrophic nitrite-oxidizing bacterium Nitrobacter winogradskyi Nb-255." Starkenburg S.R., Chain P.S.G., Sayavedra-Soto L.A., Hauser L., Land M.L., Larimer F.W., Malfatti S.A., Klotz M.G., Bottomley P.J., Arp D.J., Hickey W.J. Appl. Environ. Microbiol. 72:2050-2063(2006) [PubMed: 16517654] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000115 Genomic DNA. Translation: ABA05509.1.
RefSeq	YP_318861.1. NC_007406.1.
3D structure databases
ProteinModelPortal	Q3SQD2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3SQD2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3677144.
GenomeReviews	Gene locus Nwi_2255 in contig CP000115_GR.
KEGG	nwi:Nwi_2255.
NMPDR	fig|323098.3.peg.1234.
PATRIC	22701444. VBINitWin102302_2534.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	DINESDW.
ProtClustDB	PRK05672.
Enzyme and pathway databases
BioCyc	NWIN323098:NWI_2255-MONOMER.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3SQD2_NITWN

Accession

Primary (citable) accession number: Q3SQD2

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)