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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei159UniRule annotation1
Active sitei590UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciNWIN323098:G1G55-2344-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Nwi_2278Imported
OrganismiNitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)Imported
Taxonomic identifieri323098 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter
Proteomesi
  • UP000002531 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi323098.Nwi_2278

Structurei

3D structure databases

ProteinModelPortaliQ3SQA9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q3SQA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLMPLPRA GQPESDAADL DARLRDDIRL LGRILGDTVR DREGPEAFDL
60 70 80 90 100
VERIRQTSIR FHRDDDKPAR RELEAILDGM STDETVLVVR AFSYFSHLAN
110 120 130 140 150
IAEDQNNIRQ MRSQTLAGGA RHQGRLAHTL ACARKAGFSA AELRDFFDSA
160 170 180 190 200
VVSPVLTAHP TEVRRKSTID REMEVAALLD RRERMQLTPD EYEASEEQLR
210 220 230 240 250
RAVLTLWQTD LLRRTKLTVL DEVANGLSFY DYTFLREVPR LHCMLEDRLH
260 270 280 290 300
DPEESSAANE IASFLRIGSW IGGDRDGNPF VTADVMRGTL HWQVSRILRH
310 320 330 340 350
YLDELHELGR ELSLAADLTD VSPELSSLAE RSADTSPHRR SEPYRLAVSG
360 370 380 390 400
IYARLSATAV KLKADTLRPP YGAAPPYASA AEFSADLDIL HHSLTANNSE
410 420 430 440 450
VIARGRLRKL RRAADCFGFH LACLDLRQNS TVHERTIAEL LAAASPGTSY
460 470 480 490 500
LTLDEEARIV LLLRELRSAR PLTSPFITYS EETQGELAVF HAAAEAHGTL
510 520 530 540 550
GPDAIPQCIV SMTEGISDLL EVALLLKEAD LVDPTGHSAI NIVPLFETIE
560 570 580 590 600
DLQACAGIMD RLLSLPEYRA LVDSRGGLQE VMLGYSDSNK DGGFVTSGWE
610 620 630 640 650
LYKAEIGLVE VFERHKVRLR LFHGRGGSVG RGGGPSYDAI LAQPGGAVNG
660 670 680 690 700
QIRITEQGEI ISSKYSNAEV GRSNLEILAA ATLEASLLQP RQSAPSLEYL
710 720 730 740 750
DAMESLSSLA YKAYRNLVFE TPGFEDYFWA STVINEISTL NIGSRPASRK
760 770 780 790 800
KTRRIEDLRA IPWVFSWAQC RVMLPGWYGF GSAVEAWIES HPDKGMAFLQ
810 820 830 840 850
ELYGEWPFFR MLLSNMDMVL AKSSIAIASR YADLVPDVEL REAIFGRIRR
860 870 880 890 900
EWHLTIDKLL AIMGQERLLA GNPLLERSIR NRFPYLDPLN HVQVELLKDH
910 920
RAQCEDEQVL RGIQLTINGI SAGLRNSG
Length:928
Mass (Da):103,516
Last modified:October 11, 2005 - v1
Checksum:i086D73A411023D76
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000115 Genomic DNA Translation: ABA05532.1
RefSeqiWP_011315499.1, NC_007406.1

Genome annotation databases

EnsemblBacteriaiABA05532; ABA05532; Nwi_2278
KEGGinwi:Nwi_2278

Similar proteinsi

Entry informationi

Entry nameiQ3SQA9_NITWN
AccessioniPrimary (citable) accession number: Q3SQA9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: March 28, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health