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Protein
Submitted name:

Adenylyl cyclase class-3/4/guanylyl cyclase

Gene

Nwi_3040

Organism
Nitrobacter winogradskyi (strain Nb-255 / ATCC 25391)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. adenylate cyclase activity Source: UniProtKB-EC
  2. signal transducer activity Source: InterPro

GO - Biological processi

  1. intracellular signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseImported

Enzyme and pathway databases

BioCyciNWIN323098:GJEG-3093-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylyl cyclase class-3/4/guanylyl cyclaseImported (EC:4.6.1.1Imported)
Gene namesi
Ordered Locus Names:Nwi_3040Imported
OrganismiNitrobacter winogradskyi (strain Nb-255 / ATCC 25391)Imported
Taxonomic identifieri323098 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter
ProteomesiUP000002531: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi323098.Nwi_3040.

Structurei

3D structure databases

ProteinModelPortaliQ3SN51.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG3850.
HOGENOMiHOG000272517.
KOiK01768.
OMAiVFCDLRG.
OrthoDBiEOG6G4VQG.

Family and domain databases

Gene3Di3.30.450.40. 1 hit.
3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003660. HAMP_linker_domain.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF13492. GAF_3. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00065. GAF. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
SSF55781. SSF55781. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3SN51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEAENNSRS PRRGLFVKYV MSLVGLVLFV LAVNGALEIW ISYNQTKTAL
60 70 80 90 100
VQAMSEKADA AAHRISQAMV DLERQVSWVT RASVVTVEQR RADYAELLNQ
110 120 130 140 150
VPAVDRIFQL DGSGREQLRL SRRSVLVGSG ADFSRDARFT RTIAQGVTYA
160 170 180 190 200
PVFFRDRRPF MSIAVAHAGR DAGASVAEVD LRFLSGYVDD AQGGKAGSAY
210 220 230 240 250
VVDASGILLA SSDKTTHPGE NLSSRPQVAS LLNAGHGSSA SGTNNQGQAV
260 270 280 290 300
LTASSPVSTL RWFVVLEQPA SLAFAPILDL LIRIGILVAF GLVVAIIAGM
310 320 330 340 350
LLARRMLVPI QALSGGARRL GAGDFGHRID IKTGDELEQL AERFNSMAGQ
360 370 380 390 400
LQETYSDLEL KVKERTRDLA QSVNELKVLE EVGRAVVSSL DLEAVLSTVA
410 420 430 440 450
ARALEITKAD AVLIYGFDAG SRRFDLVQAS GIEKSAPGDH LVIGSDDSLL
460 470 480 490 500
GAAAANGQSI AIEDLASAEA NPLNEVAASA GFRSVLVVPL VDQQGVLGSL
510 520 530 540 550
IMLRRSAGAF SPNLVGLMQT FAHQAASAMR NARLFHEVDR KGKELAIAHG
560 570 580 590 600
VVQQQADKLQ EQTYRLLNWN RSLEERVEAQ LGEIERIRRL ERFLAPQVAQ
610 620 630 640 650
IVASSDGQNS LLDSHRGEVT VVFCDLRGFT AFTESSEPEE AMNVLREYHA
660 670 680 690 700
ALGELIFKYE GTLDRYAGDG VMVLFNAPVP VPDHTPRAIR MAVEMRDAIG
710 720 730 740 750
LLSQKWRSRG HSLGFSVGIA VGYATLGQVG FERRLEYAAI GSVTNLASRL
760 770 780 790 800
CDEAKAGQIV VNQRAYGMVE HLVEAAELAP MVLKGFHHPI VAVEIHRWRD
810
PAEGGSVRSA AGRTA
Length:815
Mass (Da):87,961
Last modified:October 11, 2005 - v1
Checksum:i2E3414096DA9A6EF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000115 Genomic DNA. Translation: ABA06290.1.
RefSeqiWP_011316206.1. NC_007406.1.
YP_319642.1. NC_007406.1.

Genome annotation databases

EnsemblBacteriaiABA06290; ABA06290; Nwi_3040.
GeneIDi3676349.
KEGGinwi:Nwi_3040.
PATRICi22703248. VBINitWin102302_3428.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000115 Genomic DNA. Translation: ABA06290.1.
RefSeqiWP_011316206.1. NC_007406.1.
YP_319642.1. NC_007406.1.

3D structure databases

ProteinModelPortaliQ3SN51.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi323098.Nwi_3040.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA06290; ABA06290; Nwi_3040.
GeneIDi3676349.
KEGGinwi:Nwi_3040.
PATRICi22703248. VBINitWin102302_3428.

Phylogenomic databases

eggNOGiCOG3850.
HOGENOMiHOG000272517.
KOiK01768.
OMAiVFCDLRG.
OrthoDBiEOG6G4VQG.

Enzyme and pathway databases

BioCyciNWIN323098:GJEG-3093-MONOMER.

Family and domain databases

Gene3Di3.30.450.40. 1 hit.
3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003660. HAMP_linker_domain.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF13492. GAF_3. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00065. GAF. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
SSF55781. SSF55781. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the chemolithoautotrophic nitrite-oxidizing bacterium Nitrobacter winogradskyi Nb-255."
    Starkenburg S.R., Chain P.S.G., Sayavedra-Soto L.A., Hauser L., Land M.L., Larimer F.W., Malfatti S.A., Klotz M.G., Bottomley P.J., Arp D.J., Hickey W.J.
    Appl. Environ. Microbiol. 72:2050-2063(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nb-255 / ATCC 25391Imported.

Entry informationi

Entry nameiQ3SN51_NITWN
AccessioniPrimary (citable) accession number: Q3SN51
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: January 7, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.