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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Thiobacillus denitrificans (strain ATCC 25259)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciTDEN292415:G1G56-170-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:Tbd_0168
OrganismiThiobacillus denitrificans (strain ATCC 25259)
Taxonomic identifieri292415 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesThiobacillaceaeThiobacillus
Proteomesi
  • UP000008291 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000121021 – 273Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST273

Interactioni

Protein-protein interaction databases

STRINGi292415.Tbd_0168

Structurei

3D structure databases

ProteinModelPortaliQ3SMC6
SMRiQ3SMC6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.101 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

Q3SMC6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTYAIGDIQ GCHEPLLRLL DVVRFDAASD RLWFVGDLVN RGPDSLETLR
60 70 80 90 100
FIRGLGDAAV CVLGNHDLHL IALAAGHGRA HKGDTLDAVL AAPDRDELLG
110 120 130 140 150
WLRRQKLAWR EGDWLMVHAG VLPGWTADEV MRHAAEAEAV LAGAHYRDFL
160 170 180 190 200
AQMYGNAPVA WDDGLEGVER LRVIVNAFTR LRYCSAAGEM EFHHKGAPGT
210 220 230 240 250
QPSGWLPWFD VPARKSADLA VVFGHWSTLG LVNRDDLIAL DTGCLWGGAL
260 270
SAVRLEDRQV FAVKCRQARS PTG
Length:273
Mass (Da):29,958
Last modified:October 11, 2005 - v1
Checksum:i72F07744C77BEC88
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000116 Genomic DNA Translation: AAZ96121.1
RefSeqiWP_011310681.1, NC_007404.1

Genome annotation databases

EnsemblBacteriaiAAZ96121; AAZ96121; Tbd_0168
KEGGitbd:Tbd_0168

Similar proteinsi

Entry informationi

Entry nameiAPAH_THIDA
AccessioniPrimary (citable) accession number: Q3SMC6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 11, 2005
Last modified: March 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome