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Protein

Probable chorismate pyruvate-lyase

Gene

ubiC

Organism
Thiobacillus denitrificans (strain ATCC 25259)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

Catalytic activityi

Chorismate = 4-hydroxybenzoate + pyruvate.

Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei81Substrate1
Binding sitei119Substrate; via amide nitrogen1
Binding sitei178Substrate1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processUbiquinone biosynthesis
LigandPyruvate

Enzyme and pathway databases

UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable chorismate pyruvate-lyase (EC:4.1.3.40)
Short name:
CL
Short name:
CPL
Gene namesi
Name:ubiC
Ordered Locus Names:Tbd_0464
OrganismiThiobacillus denitrificans (strain ATCC 25259)
Taxonomic identifieri292415 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesThiobacillaceaeThiobacillus
Proteomesi
  • UP000008291 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002405781 – 187Probable chorismate pyruvate-lyaseAdd BLAST187

Interactioni

Protein-protein interaction databases

STRINGi292415.Tbd_0464.

Structurei

3D structure databases

ProteinModelPortaliQ3SLJ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UbiC family.

Phylogenomic databases

eggNOGiENOG410807V. Bacteria.
COG3161. LUCA.
HOGENOMiHOG000137785.
KOiK03181.
OMAiELWGRRS.
OrthoDBiPOG091H047C.

Family and domain databases

Gene3Di3.40.1410.10. 1 hit.
HAMAPiMF_01632. UbiC. 1 hit.
InterProiView protein in InterPro
IPR007440. Chorismate--pyruvate_lyase.
IPR028978. Chorismate_lyase_/UTRA_dom_sf.
PfamiView protein in Pfam
PF04345. Chor_lyase. 1 hit.
SUPFAMiSSF64288. SSF64288. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3SLJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIATRDDVCR QAGLQYGWLP HAFQAPRTLR GWLSDRGSLT QRLRSRYRDF
60 70 80 90 100
RVLPVLRGVA APFPDESGAL GLARDASAYV RDVLLLGDGK ARVFAHSVLP
110 120 130 140 150
RAALRGGWNG IARLGTRPLG EALFRTPRVR RLAMTMRRVD ARHPLYCAAR
160 170 180
RHAEVAERAL WARRSVFCLD GHPLLVSEVF LPALLTP
Length:187
Mass (Da):20,943
Last modified:October 11, 2005 - v1
Checksum:iAAF7FD009F4DF260
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000116 Genomic DNA. Translation: AAZ96417.1.

Genome annotation databases

EnsemblBacteriaiAAZ96417; AAZ96417; Tbd_0464.
KEGGitbd:Tbd_0464.

Similar proteinsi

Entry informationi

Entry nameiUBIC_THIDA
AccessioniPrimary (citable) accession number: Q3SLJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 11, 2005
Last modified: November 22, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families