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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Thiobacillus denitrificans (strain ATCC 25259)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei148 – 1481UniRule annotation
Active sitei597 – 5971UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciTDEN292415:GHWG-645-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Tbd_0630Imported
OrganismiThiobacillus denitrificans (strain ATCC 25259)Imported
Taxonomic identifieri292415 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaHydrogenophilalesHydrogenophilaceaeThiobacillus
ProteomesiUP000008291 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi292415.Tbd_0630.

Structurei

3D structure databases

ProteinModelPortaliQ3SL36.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3SL36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAPQNLLTD DDLRAQVKLL GTLLGQVLLQ FAGEDVFEAV ETLRRGFADL
60 70 80 90 100
QQQEDQQRRS ELMAMIDAMP AGKIELVVRA FSSYFMLVNV AEESFAHRNR
110 120 130 140 150
RRMLSHGMTL WEGSFDHTLA DLKAQGLSAG TLQGLINRLH FAPVFTAHPT
160 170 180 190 200
EARRRAVMEA MRRIFLICDQ LYSPSLGVND QRELEAQLAA EIQIMWRTDE
210 220 230 240 250
LRSAKLEVRD EVRNGLYYVR ESLFEAVPKA YSFFERALRK HYGVNGDGAA
260 270 280 290 300
PISVPSFIRF GSWIGGDRDG NPFVTADVTE WTVHTQMQAA LDEYRARVRE
310 320 330 340 350
LRQTLTHSSG WCTPSAPFLE RLAEYEAEFG EQVFRGTAVQ IYSREPYRRM
360 370 380 390 400
AAMMLARLDA NLSYVHQCLA DVPSFTSHLA YEDAAAFLAD LYLIRDSLIS
410 420 430 440 450
HGDRIIAMQD LQALIRLVES FGFHLLQLDI RQESTIHTRT VAAVLQQIDP
460 470 480 490 500
DFDYKGADEA ERLKRLSAWT GHIDPIEIDD SLLDDEARET VAVFRRMAKL
510 520 530 540 550
KSEVGDEVFG TYIISMTHSA SHVMEVMLLA RLVGLCGHNG DAWFCRILVA
560 570 580 590 600
PLFETVDDLQ RSQAILDELL SNKVYRALVA ADGNRQEVML GYSDSCKDGG
610 620 630 640 650
ILASNWNLYQ AQLSIIALTR RHGVECRLFH GRGGTVGRGG GPTHEAILSQ
660 670 680 690 700
PPGTVNGEIK FTEQGEMLYY KYSNPETANY EIGMGVTGLL KASATLLKKC
710 720 730 740 750
EVRYPQDYLD WMRDIAAAGE TTYRALIATP GFIDYFYENT PVTEIGTLNI
760 770 780 790 800
GSRPSHRKKA DRSLGSIRAI PWVFGWAQSR HTLPAWYGIG SALKSFVDQH
810 820 830 840 850
PEGLAHLRAM YAEWPFFRGL LSNVQMALTK ADMEIAEEYA RLCDHPGTPD
860 870 880 890 900
IYRAIADEFA LTVAGVKQVA QIENLLEDNQ PLALSISRRR PYIDPINHIQ
910 920 930
VRLLKRYRSE SVWESEQDSW LTPLKRSINA IAAGMRNTG
Length:939
Mass (Da):105,809
Last modified:October 11, 2005 - v1
Checksum:iB0DFA494AB98D6BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000116 Genomic DNA. Translation: AAZ96583.1.
RefSeqiWP_011311142.1. NC_007404.1.

Genome annotation databases

EnsemblBacteriaiAAZ96583; AAZ96583; Tbd_0630.
KEGGitbd:Tbd_0630.
PATRICi23967419. VBIThiDen82923_0630.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000116 Genomic DNA. Translation: AAZ96583.1.
RefSeqiWP_011311142.1. NC_007404.1.

3D structure databases

ProteinModelPortaliQ3SL36.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi292415.Tbd_0630.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ96583; AAZ96583; Tbd_0630.
KEGGitbd:Tbd_0630.
PATRICi23967419. VBIThiDen82923_0630.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciTDEN292415:GHWG-645-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of the obligately chemolithoautotrophic, facultatively anaerobic bacterium Thiobacillus denitrificans."
    Beller H.R., Chain P.S., Letain T.E., Chakicherla A., Larimer F.W., Richardson P.M., Coleman M.A., Wood A.P., Kelly D.P.
    J. Bacteriol. 188:1473-1488(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25259Imported.

Entry informationi

Entry nameiQ3SL36_THIDA
AccessioniPrimary (citable) accession number: Q3SL36
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 22, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.