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Q3SK65 (G6PI1_THIDA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase 1

Short name=GPI 1
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase 1
Short name=PGI 1
Phosphohexose isomerase 1
Short name=PHI 1
Gene names
Name:pgi1
Ordered Locus Names:Tbd_0974
OrganismThiobacillus denitrificans (strain ATCC 25259) [Complete proteome] [HAMAP]
Taxonomic identifier292415 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaHydrogenophilalesHydrogenophilaceaeThiobacillus

Protein attributes

Sequence length550 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 550550Glucose-6-phosphate isomerase 1 HAMAP-Rule MF_00473
PRO_0000230939

Sites

Active site3531Proton donor By similarity
Active site3841 By similarity
Active site5121 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q3SK65 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 46D040BDA2F8EEBF

FASTA55061,247
        10         20         30         40         50         60 
MKPLKTLPAW KALEQHFKSM RNFDMRAAFR EDAARFETLS LRCGNLLLDY SKNRVTQETM 

        70         80         90        100        110        120 
RHLAQLARES ELEEMRNAMC TGERINFTEK RAVLHVALRA PVRPALMVEG VDVEREIAKV 

       130        140        150        160        170        180 
LHRMQRFVES VHNGSWRGHT GKPIRNVVNI GIGGSDLGPA MVCHALDHYA VENVRVHFVS 

       190        200        210        220        230        240 
NLDPSHLAGT LAQLDPETTL FIVASKTFTT LETLANANSA KAWLLAALRA PEAVARHFVA 

       250        260        270        280        290        300 
LSTNAQAVEA FGIDPENMFI FWDWVGGRYS LWSAIGLSIA LQIGWGNFQA LLAGAHAMDV 

       310        320        330        340        350        360 
HFKEAPLEAN MPVILGMLGI WYANFWGTDT YGVFPYDQRL RLLVPFLQQL DMESNGKNVN 

       370        380        390        400        410        420 
RANKLVNYNT GPIVWGAPGT NGQHAFFELV HQGTRLIPTD FLVAAVNLTP LADQHEWLLA 

       430        440        450        460        470        480 
NCLAQTEALL KGKSRAVIEA ELIAQGMTRD DARALAPHKV FPGNRPSNTL LYQKLDPHTL 

       490        500        510        520        530        540 
GMLIALYEHK VFVQGVIWQI NSFDQWGVEL GKQLAPPIRA ALSSVRVIGE HDGSTQGLIA 

       550 
DIRRRRGLST 

« Hide

References

[1]"The genome sequence of the obligately chemolithoautotrophic, facultatively anaerobic bacterium Thiobacillus denitrificans."
Beller H.R., Chain P.S., Letain T.E., Chakicherla A., Larimer F.W., Richardson P.M., Coleman M.A., Wood A.P., Kelly D.P.
J. Bacteriol. 188:1473-1488(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25259.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000116 Genomic DNA. Translation: AAZ96927.1.
RefSeqYP_314732.1. NC_007404.1.

3D structure databases

ProteinModelPortalQ3SK65.
SMRQ3SK65. Positions 3-547.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING292415.Tbd_0974.

Proteomic databases

PRIDEQ3SK65.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ96927; AAZ96927; Tbd_0974.
GeneID3671197.
KEGGtbd:Tbd_0974.
PATRIC23968095. VBIThiDen82923_0959.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMALMVTHAL.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycTDEN292415:GHWG-999-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI1_THIDA
AccessionPrimary (citable) accession number: Q3SK65
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: October 11, 2005
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways