aat

Functionⁱ

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityⁱ

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation

L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

Enzyme and pathway databases

BioCycⁱ	TDEN292415:GHWG-2089-MONOMER.

BioCycⁱ

TDEN292415:GHWG-2089-MONOMER.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation Manual assertion according to rulesⁱ HAMAP-Rule:MF_00688 (EC:2.3.2.6UniRule annotation Manual assertion according to rulesⁱ HAMAP-Rule:MF_00688 ) Alternative name(s): L/F-transferaseUniRule annotation Manual assertion according to rulesⁱ HAMAP-Rule:MF_00688 LeucyltransferaseUniRule annotation Manual assertion according to rulesⁱ HAMAP-Rule:MF_00688 PhenyalanyltransferaseUniRule annotation Manual assertion according to rulesⁱ HAMAP-Rule:MF_00688
Gene namesⁱ	Name:aatUniRule annotation Manual assertion according to rulesⁱ HAMAP-Rule:MF_00688 Ordered Locus Names:Tbd_2043
Organismⁱ	Thiobacillus denitrificans (strain ATCC 25259)
Taxonomic identifierⁱ	292415 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Hydrogenophilales › Hydrogenophilaceae › Thiobacillus › Thiobacillus denitrificans
Proteomesⁱ	UP000008291 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00688

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Cytoplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Chainⁱ	1 – 228	228	Leucyl/phenylalanyl-tRNA--protein transferase		PRO_0000258106	Add BLAST

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	292415.Tbd_2043.

STRINGⁱ

292415.Tbd_2043.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q3SH93.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4108R4Z. Bacteria. COG2360. LUCA.
HOGENOMⁱ	HOG000102325.
KOⁱ	K00684.
OMAⁱ	YRQGIFP.
OrthoDBⁱ	POG091H045I.

Family and domain databases

HAMAPⁱ	MF_00688. Leu_Phe_trans. 1 hit.
InterProⁱ	IPR016181. Acyl_CoA_acyltransferase. IPR004616. Leu/Phe-tRNA_Trfase. [Graphical view]
Pfamⁱ	PF03588. Leu_Phe_trans. 1 hit. [Graphical view]
SUPFAMⁱ	SSF55729. SSF55729. 1 hit.
TIGRFAMsⁱ	TIGR00667. aat. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q3SH93-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKEPFTNASY FPPVETALVD PNGLLAIGGD LSQERLLDAY RHGIFPWFNP 
        60         70         80         90        100
REPIQWWSPD PRMVLPPAEI RVTRSLAKRL RNAGFELRVD SAFIEVMRAC 
       110        120        130        140        150
GAPREGAWGT WISAPMIAAY GRLFDAGYAH SIETWRDGRL VGGLYGVAIG 
       160        170        180        190        200
RMFYGESMFS REPDASKVAL VRLARQLERW GFGLIDCQME TPHLASMGAR 
       210        220 
PIPRADFTAR LAELVNLPHL PGPWTFDS

Length:228

Mass (Da):25,573

Last modified:October 11, 2005 - v1

Checksum:ⁱDF5F323088BCA553

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000116 Genomic DNA. Translation: AAZ97996.1.
RefSeqⁱ	WP_011312555.1. NC_007404.1.

Genome annotation databases

EnsemblBacteriaⁱ	AAZ97996; AAZ97996; Tbd_2043.
KEGGⁱ	tbd:Tbd_2043.
PATRICⁱ	23970261. VBIThiDen82923_2021.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000116 Genomic DNA. Translation: AAZ97996.1.
RefSeqⁱ	WP_011312555.1. NC_007404.1.

3D structure databases

ProteinModelPortalⁱ	Q3SH93.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	292415.Tbd_2043.

STRINGⁱ

292415.Tbd_2043.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAZ97996; AAZ97996; Tbd_2043.
KEGGⁱ	tbd:Tbd_2043.
PATRICⁱ	23970261. VBIThiDen82923_2021.

Phylogenomic databases

eggNOGⁱ	ENOG4108R4Z. Bacteria. COG2360. LUCA.
HOGENOMⁱ	HOG000102325.
KOⁱ	K00684.
OMAⁱ	YRQGIFP.
OrthoDBⁱ	POG091H045I.

Enzyme and pathway databases

BioCycⁱ	TDEN292415:GHWG-2089-MONOMER.

BioCycⁱ

TDEN292415:GHWG-2089-MONOMER.

Family and domain databases

HAMAPⁱ	MF_00688. Leu_Phe_trans. 1 hit.
InterProⁱ	IPR016181. Acyl_CoA_acyltransferase. IPR004616. Leu/Phe-tRNA_Trfase. [Graphical view]
Pfamⁱ	PF03588. Leu_Phe_trans. 1 hit. [Graphical view]
SUPFAMⁱ	SSF55729. SSF55729. 1 hit.
TIGRFAMsⁱ	TIGR00667. aat. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

LFTR_THIDA

Accessionⁱ

Primary (citable) accession number: Q3SH93

Entry historyⁱ

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	October 11, 2005
Last modified:	September 7, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q3SH93 (LFTR_THIDA)

UniProt

Q3SH93 - LFTR_THIDA

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Leucyl/phenylalanyl-tRNA--protein transferase

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<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ