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Protein

Glycogen synthase

Gene

glgA

Organism
Thiobacillus denitrificans (strain ATCC 25259)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathway:iglycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciTDEN292415:GHWG-2103-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:Tbd_2057
OrganismiThiobacillus denitrificans (strain ATCC 25259)
Taxonomic identifieri292415 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaHydrogenophilalesHydrogenophilaceaeThiobacillus
ProteomesiUP000008291 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 493493Glycogen synthasePRO_0000230269Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi292415.Tbd_2057.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294941.
KOiK00703.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3SH79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLFVASEA FPLVKTGGLG DVLHGLPQAL HGLGVGVRLL LPGYRTLLRQ
60 70 80 90 100
LDQVRIVAWF DVRGAEGPVA ARVLETRHPG FDFPLWIVDC PPLFDRPGNP
110 120 130 140 150
YVDVTGYDWP DNAERFAVFA RVAALLAQDA HEAGWLPDVV HTHDWQTGLV
160 170 180 190 200
PAFLADLPAR PRTVFTIHNL AYGGHFPHGD FLRLQLPAHW WSHEGVEFHG
210 220 230 240 250
GFSMLKAGIV YADAVTTVSP TYAEEICTPA FGYGLDGLLR SRRHKLHGIL
260 270 280 290 300
NGIDSATWDP ADDPHLRARY TAGRILPGKR RDKQALLERF LPAADEAALQ
310 320 330 340 350
APLVGLVGRL VEQKGIDWVL AAMPLLLAET DARFVLLGSG QAAYEQRLTR
360 370 380 390 400
LARQHPTRVF VEIGYDEALA HQIEAGADMF LMPSRFEPCG LNQMYSLRYG
410 420 430 440 450
TLPIVFKTGG LADTIVDTNE ASLADGSANG FVFDTPDVAH FVDAVRRALA
460 470 480 490
LYRQPSLWRR VQQTGMRLSF DWRESAGHYL ALYAADSAGE PDV
Length:493
Mass (Da):54,401
Last modified:April 4, 2006 - v2
Checksum:i066D5448E75CEADA
GO

Sequence cautioni

The sequence AAZ98010.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000116 Genomic DNA. Translation: AAZ98010.1. Different initiation.
RefSeqiWP_041432692.1. NC_007404.1.

Genome annotation databases

EnsemblBacteriaiAAZ98010; AAZ98010; Tbd_2057.
KEGGitbd:Tbd_2057.
PATRICi23970289. VBIThiDen82923_2035.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000116 Genomic DNA. Translation: AAZ98010.1. Different initiation.
RefSeqiWP_041432692.1. NC_007404.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi292415.Tbd_2057.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ98010; AAZ98010; Tbd_2057.
KEGGitbd:Tbd_2057.
PATRICi23970289. VBIThiDen82923_2035.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294941.
KOiK00703.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciTDEN292415:GHWG-2103-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of the obligately chemolithoautotrophic, facultatively anaerobic bacterium Thiobacillus denitrificans."
    Beller H.R., Chain P.S., Letain T.E., Chakicherla A., Larimer F.W., Richardson P.M., Coleman M.A., Wood A.P., Kelly D.P.
    J. Bacteriol. 188:1473-1488(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25259.

Entry informationi

Entry nameiGLGA_THIDA
AccessioniPrimary (citable) accession number: Q3SH79
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: July 22, 2015
This is version 57 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.