Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Numb

Gene

Numb

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
NumbImported
Gene namesi
Name:NumbImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620107. Numb.

PTM / Processingi

PTM databases

iPTMnetiQ3MUI1.

Expressioni

Gene expression databases

GenevisibleiQ3MUI1. RN.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
Ap2a2Q66HM22EBI-7007865,EBI-2255846
Ap2b1P62944-22EBI-7007865,EBI-7008032
YwhahP685113EBI-7007865,EBI-444647

Protein-protein interaction databases

IntActiQ3MUI1. 6 interactions.
MINTiMINT-3375291.

Structurei

3D structure databases

ProteinModelPortaliQ3MUI1.
SMRiQ3MUI1. Positions 21-161.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini37 – 162126PIDInterPro annotationAdd
BLAST

Phylogenomic databases

HOVERGENiHBG006672.
KOiK06057.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR016698. Numb/numb-like.
IPR010449. Numb_domain.
IPR011993. PH_dom-like.
IPR006020. PTB/PI_dom.
[Graphical view]
PfamiPF06311. NumbF. 1 hit.
PF00640. PID. 1 hit.
[Graphical view]
PIRSFiPIRSF017607. Numb/numb-like. 1 hit.
SMARTiSM00462. PTB. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
PROSITEiPS01179. PID. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3MUI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKLRQSFRR KKDVYVPEAS RPHQWQTDEE GVRTGKCSFP VKYLGHVEVD
60 70 80 90 100
ESRGMHICED AVKRLKATGK KAVKAVLWVS ADGLRVVDEK TKDLIVDQTI
110 120 130 140 150
EKVSFCAPDR NFDRAFSYIC RDGTTRRWIC HCFMAVKDTG ERLSHAVGCA
160 170 180 190 200
FAACLERKQK REKECGVTAT FDASRTTFTR EGSFRVTTAT EQAEREEIMK
210 220 230 240 250
QLQDAKKAET DKTVGPSVAP GNSAPSPSSP TSPTLDPTAS LEMNNPHAIP
260 270 280 290 300
RRHAPIEQLA RQGSFRGFPA LSQKMSPFKR QLSLRINELP STMQRKTDFP
310 320 330 340 350
IKNTVPEVEG EAESISSLCS QITSAFSTPC EDPFSSAPMT KPVTLVAPQS
360 370 380 390 400
PVLQGTEWGQ SSGAASPGLF QAGHRRTPSE ADRWLEEVSK SVRAQQPQAS
410 420 430 440 450
AAPLQPVLQP PPPAAIAPPA PPFQGHAFLT SQPVPVGVVP PLQPAFVSTQ
460 470 480 490 500
SYPVANGMPY PASNVPVVGI TPSQMVANVF GTAGHPQATH PHQSPSLAKQ
510 520 530 540 550
QTFPQYETSS ATTSPFFKPS AQHLNGSAAF NGVDNSGLVS GNRPAQVPPG
560 570 580 590
TCPVDPFEAQ WAALESKPKQ RTNPSPTNPF SSDAQKAFEI EL
Length:592
Mass (Da):64,256
Last modified:October 25, 2005 - v1
Checksum:i774260F3D736930F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB210108 mRNA. Translation: BAE45130.1.
RefSeqiNP_579821.1. NM_133287.1.
UniGeneiRn.102078.

Genome annotation databases

GeneIDi29419.
KEGGirno:29419.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB210108 mRNA. Translation: BAE45130.1.
RefSeqiNP_579821.1. NM_133287.1.
UniGeneiRn.102078.

3D structure databases

ProteinModelPortaliQ3MUI1.
SMRiQ3MUI1. Positions 21-161.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ3MUI1. 6 interactions.
MINTiMINT-3375291.

PTM databases

iPTMnetiQ3MUI1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi29419.
KEGGirno:29419.

Organism-specific databases

CTDi8650.
RGDi620107. Numb.

Phylogenomic databases

HOVERGENiHBG006672.
KOiK06057.

Gene expression databases

GenevisibleiQ3MUI1. RN.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR016698. Numb/numb-like.
IPR010449. Numb_domain.
IPR011993. PH_dom-like.
IPR006020. PTB/PI_dom.
[Graphical view]
PfamiPF06311. NumbF. 1 hit.
PF00640. PID. 1 hit.
[Graphical view]
PIRSFiPIRSF017607. Numb/numb-like. 1 hit.
SMARTiSM00462. PTB. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
PROSITEiPS01179. PID. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Phosphorylation of Numb family proteins. Possible involvement of Ca2+/calmodulin-dependent protein kinases."
    Tokumitsu H., Hatano N., Inuzuka H., Sueyoshi Y., Yokokura S., Ichimura T., Nozaki N., Kobayashi R.
    J. Biol. Chem. 280:35108-35118(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ3MUI1_RAT
AccessioniPrimary (citable) accession number: Q3MUI1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: June 8, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.