Q3MS94 (Q3MS94_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dominant-negative kinase-deficient Brutons tyrosine kinase isoform 4 EMBL CAJ19684.1

Gene names

Name:

BTK kinase deficient isoform 4 EMBL CAJ19684.1

Organism

Homo sapiens (Human) EMBL CAJ19684.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	197 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Kinase EMBL CAJ19684.1 Transferase
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro protein kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAJ19684.1

Sequences

	Sequence		Length	Mass (Da)
	Q3MS94 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: 936CCD7D331A1A2E	FASTA	197	22,813
	10 20 30 40 50 60 VIRHYVVCST PQSQYYLAEK HLFSTIPELI NYHQHNSAGL ISRLKYPVSQ QNKNAPSTAG 70 80 90 100 110 120 LGYGSWEIDP KDLTFLKELG TGQFGVVKYG KWRGQYDVAI KMIKEGSMSE DEFIEEAKVM 130 140 150 160 170 180 MNLSHEKLVQ LYGVCTKQRP IFIITEYMAN GCLLNYLREM RHRFQTQQLL EMCKDVCEAM 190 EYLESKQFLH RDLVCPG

References

[1]	"Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells." Feldhahn N., Rio P., Ndikung B.B.S., Liedtke S., Sprangers M., Klein F., Wernet P., Jumaa H., Hofmann W.K., Hanenberg H., Rowley J.D., Mueschen M. Proc. Natl. Acad. Sci. U.S.A. 102:13266-13271(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM051278 mRNA. Translation: CAJ19684.1.
IPI	IPI01009200.
UniGene	Hs.159494.
3D structure databases
ProteinModelPortal	Q3MS94.
SMR	Q3MS94. Positions 1-58, 66-193.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG008761.
Family and domain databases
Gene3D	3.30.505.10. 1 hit.
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. IPR000980. SH2. [Graphical view]
Pfam	PF07714. Pkinase_Tyr. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS50001. SH2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q3MS94_HUMAN

Accession

Primary (citable) accession number: Q3MS94
Secondary accession number(s): E9PHN9

Entry history

Integrated into UniProtKB/TrEMBL:	October 25, 2005
Last sequence update:	October 25, 2005
Last modified:	April 3, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.