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Protein
Submitted name:

Dominant-negative kinase-deficient Brutons tyrosine kinase isoform 8

Gene

BTK kinase deficient isoform 8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

SignaLinkiQ3MS90.

Names & Taxonomyi

Protein namesi
Submitted name:
Dominant-negative kinase-deficient Brutons tyrosine kinase isoform 8Imported
Gene namesi
Name:BTK kinase deficient isoform 8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ3MS90.

Structurei

3D structure databases

ProteinModelPortaliQ3MS90.
SMRiQ3MS90. Positions 1-58.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000172458.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
[Graphical view]
PfamiPF00017. SH2. 1 hit.
[Graphical view]
SUPFAMiSSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3MS90-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
VIRHYVVCST PQSQYYLAEK HLFSTIPELI NYHQHNSAGL ISRLKYPVSQ
60 70
QNKNAPSTAG LGYGMSWMMN TQAQ
Length:74
Mass (Da):8,400
Last modified:October 25, 2005 - v1
Checksum:i884F90B26B596F13
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM051282 mRNA. Translation: CAJ19688.1.
UniGeneiHs.159494.
Hs.733206.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM051282 mRNA. Translation: CAJ19688.1.
UniGeneiHs.159494.
Hs.733206.

3D structure databases

ProteinModelPortaliQ3MS90.
SMRiQ3MS90. Positions 1-58.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ3MS90.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000172458.

Enzyme and pathway databases

SignaLinkiQ3MS90.

Miscellaneous databases

ChiTaRSiBTK. human.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
[Graphical view]
PfamiPF00017. SH2. 1 hit.
[Graphical view]
SUPFAMiSSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ3MS90_HUMAN
AccessioniPrimary (citable) accession number: Q3MS90
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: November 26, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.