Q3MNF1 (Q3MNF1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Smooth muscle myosin heavy chain isoform SM1 EMBL AAS98910.1

Submitted name:
Uncharacterized protein Ensembl ENSP00000379616

Gene names

Name:

MYH11 EMBL AAS98910.1 Ensembl ENSP00000379616

Organism

Homo sapiens (Human) EMBL AAS98910.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1979 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 IQ domain. SAAS SAAS000048 Contains 1 myosin head-like domain. SAAS SAAS000048

Ontologies

Keywords
Domain	Coiled coil SAAS SAAS000048
Ligand	ATP-binding SAAS SAAS000048 Actin-binding SAAS SAAS000048 Nucleotide-binding
Molecular function	Motor protein Myosin SAAS SAAS000048
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	myosin complex Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW actin binding Inferred from electronic annotation. Source: UniProtKB-KW motor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3MNF1 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: 9B70CDC6279DC694	FASTA	1,979	228,090
	10 20 30 40 50 60 MAQKGQLSDD EKFLFVDKNF INSPVAQADW AAKRLVWVPS EKQGFEAASI KEEKGDEVVV 70 80 90 100 110 120 ELVENGKKVT VGKDDIQKMN PPKFSKVEDM AELTCLNEAS VLHNLRERYF SGLIYTYSGL 130 140 150 160 170 180 FCVVVNPYKH LPIYSEKIVD MYKGKKRHEM PPHIYAIADT AYRSMLQDRE DQSILCTGES 190 200 210 220 230 240 GAGKTENTKK VIQYLAVVAS SHKGKKDTSI TQGPSFAYGE LEKQLLQANP ILEAFGNAKT 250 260 270 280 290 300 VKNDNSSRFG KFIRINFDVT GYIVGANIET YLLEKSRAIR QARDERTFHI FYYMIAGAKE 310 320 330 340 350 360 KMRSDLLLEG FNNYTFLSNG FVPIPAAQDD EMFQETVEAM AIMGFSEEEQ LSILKVVSSV 370 380 390 400 410 420 LQLGNIVFKK ERNTDQASMP DNTAAQKVCH LMGINVTDFT RSILTPRIKV GRDVVQKAQT 430 440 450 460 470 480 KEQADFAVEA LAKATYERLF RWILTRVNKA LDKTHRQGAS FLGILDIAGF EIFEVNSFEQ 490 500 510 520 530 540 LCINYTNEKL QQLFNHTMFI LEQEEYQREG IEWNFIDFGL DLQPCIELIE RPNNPPGVLA 550 560 570 580 590 600 LLDEECWFPK ATDKSFVEKL CTEQGSHPKF QKPKQLKDKT EFSIIHYAGK VDYNASAWLT 610 620 630 640 650 660 KNMDPLNDNV TSLLNASSDK FVADLWKDVD RIVGLDQMAK MTESSLPSAS KTKKGMFRTV 670 680 690 700 710 720 GQLYKEQLGK LMTTLRNTTP NFVRCIIPNH EKRSGKLDAF LVLEQLRCNG VLEGIRICRQ 730 740 750 760 770 780 GFPNRIVFQE FRQRYEILAA NAIPKGFMDG KQACILMIKA LELDPNLYRI GQSKIFFRTG 790 800 810 820 830 840 VLAHLEEERD LKITDVIMAF QAMCRGYLAR KAFAKRQQQL TAMKVIQRNC AAYLKLRNWQ 850 860 870 880 890 900 WWRLFTKVKP LLQVTRQEEE MQAKEDELQK TKERQQKAEN ELKELEQKHS QLTEEKNLLQ 910 920 930 940 950 960 EQLQAETELY AEAEEMRVRL AAKKQELEEI LHEMEARLEE EEDRGQQLQA ERKKMAQQML 970 980 990 1000 1010 1020 DLEEQLEEEE AARQKLQLEK VTAEAKIKKL EDEILVMDDQ NNKLSKERKL LEERISDLTT 1030 1040 1050 1060 1070 1080 NLAEEEEKAK NLTKLKNKHE SMISELEVRL KKEEKSRQEL EKLKRKLEGD ASDFHEQIAD 1090 1100 1110 1120 1130 1140 LQAQIAELKM QLAKKEEELQ AALARLDDEI AQKNNALKKI RELEGHISDL QEDLDSERAA 1150 1160 1170 1180 1190 1200 RNKAEKQKRD LGEELEALKT ELEDTLDSTA TQQELRAKRE QEVTVLKKAL DEETRSHEAQ 1210 1220 1230 1240 1250 1260 VQEMRQKHAQ AVEELTEQLE QFKRAKANLD KNKQTLEKEN ADLAGELRVL GQAKQEVEHK 1270 1280 1290 1300 1310 1320 KKKLEAQVQE LQSKCSDGER ARAELNDKVH KLQNEVESVT GMLNEAEGKA IKLAKDVASL 1330 1340 1350 1360 1370 1380 SSQLQDTQEL LQEETRQKLN VSTKLRQLEE ERNSLQDQLD EEMEAKQNLE RHISTLNIQL 1390 1400 1410 1420 1430 1440 SDSKKKLQDF ASTVEALEEG KKRFQKEIEN LTQQYEEKAA AYDKLEKTKN RLQQELDDLV 1450 1460 1470 1480 1490 1500 VDLDNQRQLV SNLEKKQRKF DQLLAEEKNI SSKYADERDR AEAEAREKET KALSLARALE 1510 1520 1530 1540 1550 1560 EALEAKEELE RTNKMLKAEM EDLVSSKDDV GKNVHELEKS KRALETQMEE MKTQLEELED 1570 1580 1590 1600 1610 1620 ELQATEDAKL RLEVNMQALK GQFERDLQAR DEQNEEKRRQ LQRQLHEYET ELEDERKQRA 1630 1640 1650 1660 1670 1680 LAAAAKKKLE GDLKDLELQA DSAIKGREEA IKQLRKLQAQ MKDFQRELED ARASRDEIFA 1690 1700 1710 1720 1730 1740 TAKENEKKAK SLEADLMQLQ EDLAAAERAR KQADLEKEEL AEELASSLSG RNALQDEKRR 1750 1760 1770 1780 1790 1800 LEARIAQLEE ELEEEQGNME AMSDRVRKAT QQAEQLSNEL ATERSTAQKN ESARQQLERQ 1810 1820 1830 1840 1850 1860 NKELRSKLHE MEGAVKSKFK STIAALEAKI AQLEEQVEQE AREKQAATKS LKQKDKKLKE 1870 1880 1890 1900 1910 1920 ILLQVEDERK MAEQYKEQAE KGNARVKQLK RQLEEAEEES QRINANRRKL QRELDEATES 1930 1940 1950 1960 1970 NEAMGREVNA LKSKLRRGNE TSFVPSRRSG GRRVIENADG SEEETDTRDA DFNGTKASE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence and analysis of duplication-rich human chromosome 16." Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J. , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A. Nature 432:988-994(2004) [PubMed: 15616553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"(+)Insert smooth muscle myosin heavy chain (SM-B) isoform expression in human tissues." Leguillette R., Gil F.R., Zitouni N., Lajoie-Kadoch S., Sobieszek A., Lauzon A.M. Am. J. Physiol. Cell Physiol. 289:C1277-C1285(2005) [PubMed: 16000639] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC024120 Genomic DNA. No translation available. AC026401 Genomic DNA. No translation available. AC130651 Genomic DNA. No translation available. AF001548 Genomic DNA. No translation available. AY520816 mRNA. Translation: AAS98910.1.
IPI	IPI00743857.
RefSeq	NP_001035203.1. NM_001040114.1.
UniGene	Hs.460109.
3D structure databases
ProteinModelPortal	Q3MNF1.
SMR	Q3MNF1. Positions 2-820.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3MNF1.
Proteomic databases
PRIDE	Q3MNF1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000396324; ENSP00000379616; ENSG00000133392.
GeneID	4629.
KEGG	hsa:4629.
UCSC	uc002ddx.1. human.
Organism-specific databases
CTD	4629.
HGNC	HGNC:7569. MYH11.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG004704.
PhylomeDB	Q3MNF1.
Gene expression databases
ArrayExpress	Q3MNF1.
Bgee	Q3MNF1.
Family and domain databases
InterPro	IPR000048. IQ_motif_EF-hand-BS. IPR001609. Myosin_head_motor_dom. IPR004009. Myosin_N. IPR002928. Myosin_tail. [Graphical view]
KO	K10352.
Pfam	PF00063. Myosin_head. 1 hit. PF02736. Myosin_N. 1 hit. PF01576. Myosin_tail_1. 1 hit. [Graphical view]
PRINTS	PR00193. MYOSINHEAVY.
SMART	SM00015. IQ. 1 hit. SM00242. MYSc. 1 hit. [Graphical view]
PROSITE	PS50096. IQ. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	17818.

Entry information

Entry name

Q3MNF1_HUMAN

Accession

Primary (citable) accession number: Q3MNF1

Entry history

Integrated into UniProtKB/TrEMBL:	October 25, 2005
Last sequence update:	October 25, 2005
Last modified:	November 16, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.