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Q3MIF4 (XYLB_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Xylulose kinase

Short name=Xylulokinase
EC=2.7.1.17
Gene names
Name:Xylb
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length536 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis By similarity.

Catalytic activity

ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

Subunit structure

Monomer By similarity.

Sequence similarities

Belongs to the FGGY kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 536536Xylulose kinase
PRO_0000230988

Regions

Nucleotide binding441 – 4422ATP By similarity

Sites

Binding site991Substrate By similarity
Binding site1701Substrate By similarity
Binding site2801Substrate By similarity
Binding site2811Substrate By similarity
Binding site3551ATP By similarity
Binding site4451ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q3MIF4 [UniParc].

Last modified October 25, 2005. Version 1.
Checksum: 39206405B8361CB4

FASTA53657,970
        10         20         30         40         50         60 
MAERAGRRCC LGWDFSTQQV KVVAVDAELN VFYEDSVHFD RDLPEFGTQG GVHVHKDRLT 

        70         80         90        100        110        120 
VTSPVLMWVQ ALDLILEKMK ASGFDFSQVL ALSGAGQQHG SVYWKTGASL ALSSLSPALL 

       130        140        150        160        170        180 
LHQQLQACFS VSDCPIWMDS STTAQCHQLE AAVGGAQALS CLTGSRAYER FTGNQISKIF 

       190        200        210        220        230        240 
QKNPEAYSNS ERISLVSSFA ASLFLGRYSP IDYSDGSGMN LLQIQEKVWS QACLDACAPH 

       250        260        270        280        290        300 
LKEKLGSPVP SCSVVGAISS YYVQRYGFPP GCKVVAFTGD NPASLAGMRL EEGDVAVSLG 

       310        320        330        340        350        360 
TSDTLFLWLQ KPMPALEGHI FCNPVDARQY MALLCFKNGS LMREKIRDES ASCSWNKFSK 

       370        380        390        400        410        420 
ALQSTEMGNN GNLGFYFDVM EITPEIIGCH RFNADNMEVS AFPGDVEIRA LVEGQFMAKR 

       430        440        450        460        470        480 
IHAEGLGYRI MPKTKILATG GASHNKDILQ VLADVFGAPV YVIDTTSSAC VGSAYRAFHG 

       490        500        510        520        530 
LAGGTGVAFS EVVKSAPQPS LAATPNPGAS QVYAALLPRY AELEQRILSK ARGPLE 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Prostate.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC101852 mRNA. Translation: AAI01853.1.
RefSeqNP_001028876.1. NM_001033704.1.
UniGeneRn.8732.

3D structure databases

ProteinModelPortalQ3MIF4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000019106.

Proteomic databases

PaxDbQ3MIF4.
PRIDEQ3MIF4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID316067.
KEGGrno:316067.
UCSCRGD:1307372. rat.

Organism-specific databases

CTD9942.
RGD1307372. Xylb.

Phylogenomic databases

eggNOGCOG1070.
HOGENOMHOG000174850.
HOVERGENHBG053124.
InParanoidQ3MIF4.
KOK00854.
PhylomeDBQ3MIF4.

Gene expression databases

GenevestigatorQ3MIF4.

Family and domain databases

InterProIPR018485. Carb_kinase_FGGY_C.
IPR018484. Carb_kinase_FGGY_N.
[Graphical view]
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio670382.
PROQ3MIF4.

Entry information

Entry nameXYLB_RAT
AccessionPrimary (citable) accession number: Q3MIF4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: October 25, 2005
Last modified: April 16, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families