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Protein

Cysteine and glycine-rich protein 1

Gene

CSRP1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Could play a role in neuronal development.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Cysteine and glycine-rich protein 1
Alternative name(s):
Cysteine-rich protein 1
Short name:
CRP1
Gene namesi
Name:CSRP1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 16

Subcellular locationi

  • Nucleus By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000757141 – 193Cysteine and glycine-rich protein 1Add BLAST193

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei81PhosphoserineBy similarity1
Modified residuei84N6-acetyllysineBy similarity1
Modified residuei112N6-acetyllysineBy similarity1
Modified residuei131N6-acetyllysineBy similarity1
Modified residuei137N6-acetyllysineBy similarity1
Modified residuei161N6-acetyllysineBy similarity1
Modified residuei192PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ3MHY1.
PeptideAtlasiQ3MHY1.
PRIDEiQ3MHY1.

Expressioni

Gene expression databases

BgeeiENSBTAG00000016057.

Interactioni

Subunit structurei

Interacts with ASCC1; ASCC2 AND TRIP4.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000021369.

Structurei

3D structure databases

ProteinModelPortaliQ3MHY1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 61LIM zinc-binding 1PROSITE-ProRule annotationAdd BLAST52
Domaini119 – 170LIM zinc-binding 2PROSITE-ProRule annotationAdd BLAST52

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi64 – 69Nuclear localization signalSequence analysis6

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi63 – 78Gly-richAdd BLAST16
Compositional biasi176 – 187Gly-richAdd BLAST12

Sequence similaritiesi

Contains 2 LIM zinc-binding domains.PROSITE-ProRule annotation

Keywords - Domaini

LIM domain, Repeat

Phylogenomic databases

eggNOGiENOG410KDR8. Eukaryota.
ENOG4111F3Y. LUCA.
GeneTreeiENSGT00550000074548.
HOVERGENiHBG051143.
InParanoidiQ3MHY1.
KOiK09377.
OMAiRCPRCTQ.
OrthoDBiEOG091G11RX.
TreeFamiTF313758.

Family and domain databases

Gene3Di2.10.110.10. 2 hits.
InterProiIPR001781. Znf_LIM.
[Graphical view]
PfamiPF00412. LIM. 2 hits.
[Graphical view]
SMARTiSM00132. LIM. 2 hits.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3MHY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPNWGGGKKC GVCQKTVYFA EEVQCEGSSF HKSCFLCLVC KKNLDSTTVA
60 70 80 90 100
VHGEEIYCKS CYGKKYGPKG YGYGQGAGTL SMDKGESLGI RHEEAPGHRP
110 120 130 140 150
TTNPNTSKFA QKVGGSERCP RCSQAVYAAE KVIGAGKSWH KSCFRCAKCG
160 170 180 190
KGLESTTLAD KDGEIYCKGC YAKNFGPKGF GFGQGAGALV HSE
Length:193
Mass (Da):20,612
Last modified:January 23, 2007 - v3
Checksum:iD8FADEFD582B4AFC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC104539 mRNA. Translation: AAI04540.1.
RefSeqiNP_001077240.1. NM_001083771.1.
UniGeneiBt.43234.

Genome annotation databases

EnsembliENSBTAT00000021369; ENSBTAP00000021369; ENSBTAG00000016057.
GeneIDi615329.
KEGGibta:615329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC104539 mRNA. Translation: AAI04540.1.
RefSeqiNP_001077240.1. NM_001083771.1.
UniGeneiBt.43234.

3D structure databases

ProteinModelPortaliQ3MHY1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000021369.

Proteomic databases

PaxDbiQ3MHY1.
PeptideAtlasiQ3MHY1.
PRIDEiQ3MHY1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000021369; ENSBTAP00000021369; ENSBTAG00000016057.
GeneIDi615329.
KEGGibta:615329.

Organism-specific databases

CTDi1465.

Phylogenomic databases

eggNOGiENOG410KDR8. Eukaryota.
ENOG4111F3Y. LUCA.
GeneTreeiENSGT00550000074548.
HOVERGENiHBG051143.
InParanoidiQ3MHY1.
KOiK09377.
OMAiRCPRCTQ.
OrthoDBiEOG091G11RX.
TreeFamiTF313758.

Gene expression databases

BgeeiENSBTAG00000016057.

Family and domain databases

Gene3Di2.10.110.10. 2 hits.
InterProiIPR001781. Znf_LIM.
[Graphical view]
PfamiPF00412. LIM. 2 hits.
[Graphical view]
SMARTiSM00132. LIM. 2 hits.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCSRP1_BOVIN
AccessioniPrimary (citable) accession number: Q3MHY1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: January 23, 2007
Last modified: October 5, 2016
This is version 66 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.