ID   SUCB2_BOVIN             Reviewed;         432 AA.
AC   Q3MHX5;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   16-JUN-2009, entry version 32.
DE   RecName: Full=Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial;
DE            EC=6.2.1.4;
DE   AltName: Full=GTP-specific succinyl-CoA synthetase subunit beta;
DE   AltName: Full=Succinyl-CoA synthetase beta-G chain;
DE            Short=SCS-betaG;
DE   Flags: Precursor;
GN   Name=SUCLG2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: GTP + succinate + CoA = GDP + phosphate +
CC       succinyl-CoA.
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta subunit (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion (By similarity).
CC   -!- SIMILARITY: Belongs to the succinate/malate CoA ligase beta
CC       subunit family.
CC   -!- SIMILARITY: Contains 1 ATP-grasp domain.
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DR   EMBL; BC104559; AAI04560.1; -; mRNA.
DR   IPI; IPI00705618; -.
DR   RefSeq; NP_001029811.1; -.
DR   UniGene; Bt.23260; -.
DR   SMR; Q3MHX5; 38-429.
DR   Ensembl; ENSBTAG00000009541; Bos taurus.
DR   GeneID; 537713; -.
DR   KEGG; bta:537713; -.
DR   HOVERGEN; Q3MHX5; -.
DR   OMA; Q3MHX5; NEPINEA.
DR   BRENDA; 6.2.1.4; 251.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004776; F:succinate-CoA ligase (GDP-forming) activity; IEA:EC.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR013650; ATP-grasp_succ-CoA_synth-type.
DR   InterPro; IPR013816; ATP_grasp_subdomain_2.
DR   InterPro; IPR005811; CoA_ligase.
DR   InterPro; IPR017866; Succ-CoA_synthase_bsu_CS.
DR   InterPro; IPR005809; Succ_CoA_synthase_bsu.
DR   InterPro; IPR016102; Succinyl-CoA_synth-like.
DR   Gene3D; G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
DR   Gene3D; G3DSA:3.40.50.261; Succinyl-CoA_synth-like; 1.
DR   PANTHER; PTHR11815; CoA_lig_beta; 1.
DR   Pfam; PF08442; ATP-grasp_2; 1.
DR   Pfam; PF00549; Ligase_CoA; 1.
DR   TIGRFAMs; TIGR01016; sucCoAbeta; 1.
DR   PROSITE; PS50975; ATP_GRASP; FALSE_NEG.
DR   PROSITE; PS01217; SUCCINYL_COA_LIG_3; 1.
PE   2: Evidence at transcript level;
KW   GTP-binding; Ligase; Mitochondrion; Nucleotide-binding;
KW   Transit peptide; Tricarboxylic acid cycle.
FT   TRANSIT       1     37       Mitochondrion (By similarity).
FT   CHAIN        38    432       Succinyl-CoA ligase [GDP-forming] subunit
FT                                beta, mitochondrial.
FT                                /FTId=PRO_0000230989.
FT   DOMAIN       46    274       ATP-grasp.
SQ   SEQUENCE   432 AA;  46691 MW;  C3A5343FF0A65B3D CRC64;
     MAAPVGAQAR KLLRDLVLRP PLLAARSQVV QLTSRRWLNL QEYQSKKLMS DNGVKVQRFF
     VADTANEALE AAKRLNAKEI VLKAQILAGG RGKGVFSSGL KGGVHLTKDP KVVGQLAKQM
     IGYNLATKQT PKEGVKVKKV MVAEALDISR ETYLAILMDR SCNGPVLVGS PQGGVDIEEV
     AASNPELIFK EQIDIIEGIK DSQAQRMAEN LGFLGPLKNQ AADQIKKLYN LFLKIDATQV
     EVNPFGETPE GQVVCFDAKI NFDDNAEFRQ KDIFAMDDKS ENEPIENEAA RYDLKYIGLD
     GNIACFVNGA GLAMATCDII FLNGGKPANF LDLGGGVKES QVYQAFKLLT ADPKVEAILV
     NIFGGIVNCA IIANGITKAC RELELKVPLV VRLEGTNVHE AQNILSNSGL PITSAVDLED
     AAKKAVASVA KK
//