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Protein

Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2

Gene

Sohlh2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable transcription factor, which may be involved in spermatogenesis and oogenesis.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processDifferentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2
Gene namesi
Name:Sohlh2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi1589577 Sohlh2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003157021 – 462Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2Add BLAST462

Proteomic databases

PaxDbiQ3MHT3
PRIDEiQ3MHT3

Expressioni

Gene expression databases

BgeeiENSRNOG00000038091

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000049772

Structurei

3D structure databases

ProteinModelPortaliQ3MHT3
SMRiQ3MHT3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini200 – 251bHLHPROSITE-ProRule annotationAdd BLAST52

Phylogenomic databases

eggNOGiENOG410IUEE Eukaryota
ENOG410ZGUF LUCA
GeneTreeiENSGT00390000016050
HOGENOMiHOG000070147
HOVERGENiHBG103652
InParanoidiQ3MHT3
OMAiLPQHCNS
OrthoDBiEOG091G08ZT
PhylomeDBiQ3MHT3
TreeFamiTF336841

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR032669 SOHLH2
PANTHERiPTHR16223:SF16 PTHR16223:SF16, 1 hit
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

Sequencei

Sequence statusi: Complete.

Q3MHT3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADRISTGEL GRRPGQGRVD LLLVGDATRY FLAGSVQKFF SSTAQITLTI
60 70 80 90 100
SNVKKVAALL AANSFDIIFL KVTSTLTAEE QEAVRLIRSG KKKNTHLLFA
110 120 130 140 150
FVIPEKLRGY ISDYGADISF NEPLTLEKVN TVINYWKTYF TNTDMGNTEL
160 170 180 190 200
PPECRLYFQT SCSELGGHFP TDLFLCSELL NNDTGLGLKA PLSSPERNKK
210 220 230 240 250
ASFLHSSKEK LRRERIKFCC EQLRTLLPYV KGRKSDVASV IEATVDYVKQ
260 270 280 290 300
VRESLSPAIM AQITESLQSN KRFSKRQMPI ELFLPCTATS QRGDAMLTSA
310 320 330 340 350
FSPVQEIQLL ADQGLNVYSM PAAGGPLEEA VRGQPGSVSE DLYKTRVPST
360 370 380 390 400
TLSLNSFHAV RYCSGPVSPH EAAARTNQNI SIYLPPTGPS VSSFTPQHCN
410 420 430 440 450
AMLCPTRPAS SSCLCTSGHE LPASSRTASS SIFRGFRESD SGHQASQQPT
460
GPSLQPQDSS YF
Length:462
Mass (Da):50,669
Last modified:October 25, 2005 - v1
Checksum:i589BADC7ED81958F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC104697 mRNA Translation: AAI04698.1
RefSeqiNP_001030133.1, NM_001034961.1
UniGeneiRn.137450

Genome annotation databases

EnsembliENSRNOT00000044424; ENSRNOP00000049772; ENSRNOG00000038091
GeneIDi619575
KEGGirno:619575
UCSCiRGD:1589577 rat

Similar proteinsi

Entry informationi

Entry nameiSOLH2_RAT
AccessioniPrimary (citable) accession number: Q3MHT3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 25, 2005
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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