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Protein
Submitted name:

Chaperonin containing Tcp1, subunit 6A (Zeta 1)

Gene

Cct6a

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-390471 Association of TriC/CCT with target proteins during biosynthesis
R-RNO-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Names & Taxonomyi

Protein namesi
Submitted name:
Chaperonin containing Tcp1, subunit 6A (Zeta 1)Imported
Submitted name:
Chaperonin subunit 6a (Zeta)Imported
Submitted name:
Chaperonin-containing TCP1 subunit 6AImported
Gene namesi
Name:Cct6aImported
ORF Names:rCG_21714Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 12

Organism-specific databases

RGDi1304763 Cct6a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000000923

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000001227

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili250 – 270Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0359 Eukaryota
ENOG410XQ3Q LUCA
GeneTreeiENSGT00550000074743
HOGENOMiHOG000226733
HOVERGENiHBG103725
KOiK09498
OMAiMQHKTDT
OrthoDBiEOG091G07CE
TreeFamiTF106333

Family and domain databases

CDDicd03342 TCP1_zeta, 1 hit
Gene3Di1.10.560.10, 2 hits
3.50.7.10, 1 hit
InterProiView protein in InterPro
IPR012722 Chap_CCT_zeta
IPR017998 Chaperone_TCP-1
IPR002194 Chaperonin_TCP-1_CS
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PANTHERiPTHR11353 PTHR11353, 1 hit
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00304 TCOMPLEXTCP1
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 2 hits
TIGRFAMsiTIGR02347 chap_CCT_zeta, 1 hit
PROSITEiView protein in PROSITE
PS00750 TCP1_1, 1 hit
PS00751 TCP1_2, 1 hit
PS00995 TCP1_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q3MHS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAVKTLNPK AEVARAQAAL AVNISAARGL QDVLRTNLGP KGTMKMLVSG
60 70 80 90 100
AGDIKLTKDG NVLLHEMQIQ HPTASLIAKV ATAQDDITGD GTTSNVLIIG
110 120 130 140 150
ELLKQADLYI SEGLHPRIIT EGFEAAKEKA LQFLEQVKVS KEMDRETLID
160 170 180 190 200
VARTSLRTKV HAELADVLTE AVVDSILAIR KKDEPIDLFM VEIMEMKHKS
210 220 230 240 250
ETDTSLIRGL VLDHGARHPD MKKRVENAYI LTCNVSLEYE KTEVNSGFFY
260 270 280 290 300
KSAEEREKLV KAERKFIEDR VKKIVELKKK VCGDSDKGFV VINQKGIDPF
310 320 330 340 350
SLDALAKEGI VALRRAKRRN MERLTLACGG IALNSFDDLN PDCLGHAGLV
360 370 380 390 400
YEYTLGEEKF TFIEKCNNPR SVTLLVKGPN KHTLTQIKDA IRDGLRAVKN
410 420 430 440 450
AIDDGCVVPG AGAVEVALAE ALIKYKPSVK GRAQLGVQAF ADALLIIPKV
460 470 480 490 500
LAQNSGFDLQ ETLVKVQAEH SESGQLVGVD LNTGEPMVAA EMGVWDNYCV
510 520 530
KKQLLHSCTV IATNILLVDE IMRAGMSSLK G
Length:531
Mass (Da):58,017
Last modified:October 25, 2005 - v1
Checksum:iD26436B614F19642
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07036010 Genomic DNA No translation available.
BC104703 mRNA Translation: AAI04704.1
CH473973 Genomic DNA Translation: EDM13487.1
RefSeqiNP_001028856.1, NM_001033684.1
UniGeneiRn.33807

Genome annotation databases

EnsembliENSRNOT00000001227; ENSRNOP00000001227; ENSRNOG00000000923
GeneIDi288620
KEGGirno:288620

Similar proteinsi

Entry informationi

Entry nameiQ3MHS9_RAT
AccessioniPrimary (citable) accession number: Q3MHS9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: April 25, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health