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Protein

GTP-binding protein 10

Gene

GTPBP10

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in the ribosome maturation process.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi155 – 1628GTPPROSITE-ProRule annotation
Nucleotide bindingi202 – 2065GTPPROSITE-ProRule annotation
Nucleotide bindingi278 – 2814GTPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
GTP-binding protein 10
Gene namesi
Name:GTPBP10
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 4

Subcellular locationi

  • Nucleusnucleolus

  • Note: Found in the dense fibrillar compartment region of the nucleolus.By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 387387GTP-binding protein 10PRO_0000312629Add
BLAST

Proteomic databases

PaxDbiQ3MHG6.
PRIDEiQ3MHG6.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000043009.

Structurei

3D structure databases

ProteinModelPortaliQ3MHG6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini149 – 344196OBG-type GPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.PROSITE-ProRule annotation
Contains 1 OBG-type G (guanine nucleotide-binding) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1489. Eukaryota.
COG0536. LUCA.
GeneTreeiENSGT00530000063429.
HOGENOMiHOG000019084.
HOVERGENiHBG104309.
InParanoidiQ3MHG6.
OMAiNLWISDT.
OrthoDBiEOG7DJSMM.
TreeFamiTF314774.

Family and domain databases

Gene3Di2.70.210.12. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR031167. G_OBG.
IPR014100. GTP-bd_Obg/CgtA.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11702:SF3. PTHR11702:SF3. 1 hit.
PfamiPF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFiPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
PROSITEiPS51710. G_OBG. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3MHG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRCSCVLFR KYGNFIDNLR LFTKGGSGGM GYPRLGGEGG KGGDVWVVAH
60 70 80 90 100
NRMTLKQLKD KYPQKRFVAG EGANSRVSAL KGSKGKDCEI PVPVGVSVTD
110 120 130 140 150
ENGKIIGELN KEKDRLLVAE GGLGGKLLTN FLPLKGQKRV IHLDLKLIAD
160 170 180 190 200
IGLVGFPNAG KSSLLSKISH AKPAIADYAF TTIKPELGKI MYSDFKQISV
210 220 230 240 250
ADLPGLIEGA HMNKGMGHKF LKHIERTKQL LFVVDISGFQ LSSQTHYRTA
260 270 280 290 300
FETIILLSKE LELYKEELHT KPALLAVNKM DLPDAQGKFH VLMNQLQNPK
310 320 330 340 350
EFFHLFEKNM IPERTVEFQH IIPISAITGE GIDELKNCIR KSLDEHTNQE
360 370 380
NDAYHKKQLL NLHISNTVSY SEPPSKTAVS SPRMDIT
Length:387
Mass (Da):42,932
Last modified:October 25, 2005 - v1
Checksum:i30571CDBF52CD3DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC105245 mRNA. Translation: AAI05246.1.
RefSeqiNP_001073783.1. NM_001080314.1.
UniGeneiBt.63737.

Genome annotation databases

EnsembliENSBTAT00000045634; ENSBTAP00000043009; ENSBTAG00000032166.
GeneIDi613957.
KEGGibta:613957.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC105245 mRNA. Translation: AAI05246.1.
RefSeqiNP_001073783.1. NM_001080314.1.
UniGeneiBt.63737.

3D structure databases

ProteinModelPortaliQ3MHG6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000043009.

Proteomic databases

PaxDbiQ3MHG6.
PRIDEiQ3MHG6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000045634; ENSBTAP00000043009; ENSBTAG00000032166.
GeneIDi613957.
KEGGibta:613957.

Organism-specific databases

CTDi85865.

Phylogenomic databases

eggNOGiKOG1489. Eukaryota.
COG0536. LUCA.
GeneTreeiENSGT00530000063429.
HOGENOMiHOG000019084.
HOVERGENiHBG104309.
InParanoidiQ3MHG6.
OMAiNLWISDT.
OrthoDBiEOG7DJSMM.
TreeFamiTF314774.

Family and domain databases

Gene3Di2.70.210.12. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR031167. G_OBG.
IPR014100. GTP-bd_Obg/CgtA.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11702:SF3. PTHR11702:SF3. 1 hit.
PfamiPF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFiPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
PROSITEiPS51710. G_OBG. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Hypothalamus.

Entry informationi

Entry nameiGTPBA_BOVIN
AccessioniPrimary (citable) accession number: Q3MHG6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: October 25, 2005
Last modified: June 8, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.