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Protein

Histidine kinase

Gene

Ava_0083

Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphorelay sensor kinase activity Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-83-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine kinaseSAAS annotation (EC:2.7.13.3SAAS annotation)
Gene namesi
Ordered Locus Names:Ava_0083Imported
OrganismiAnabaena variabilis (strain ATCC 29413 / PCC 7937)Imported
Taxonomic identifieri240292 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeAnabaena
ProteomesiUP000002533 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ3MH27.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains histidine kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000263148.
OMAiPLIAFTM.
OrthoDBiEOG6HTNS7.

Family and domain databases

Gene3Di3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3MH27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITLPNYKIL ELIDEGVKTN VYHAISIPDG KLVVIKILKK EYPELKDIAA
60 70 80 90 100
LKHEYELIKN LDIPGVVKAH SFEKYNNYFA IVLEDFDGTC LYKVIQEKKI
110 120 130 140 150
GLLDFCKIGI QITQALGELH QNYIIHKDIK PQNIIVNLET NQVKIIDFSI
160 170 180 190 200
SSLLFQEKAK LNNPDLLEGT IAYISPEQTG RMNRSIDYRT DFYSLGVTFY
210 220 230 240 250
EMLTGQLPFV VTDPMELVHC HIARQPTKIN ELIPEIPEVV SDIIMKLLSK
260 270 280 290 300
TAEERYQSAF GIKADLEKCL NQLIESNSIT TFIIGQHDYS SQLQIPEKLY
310 320 330 340 350
GRKTEIDILM TAFENVNQGN KELILVAGYS GIGKSALVNE IHKPVIKSRG
360 370 380 390 400
YFIAGKFEQF QRNIPYASVI QAFQELIQQL LTESEQQLAN WREKILEALI
410 420 430 440 450
PNAQIIIDVI PELELIIGKQ PEVPQLGSAE AQNRFNLVMQ KFINVFAQKE
460 470 480 490 500
HPLVVFLDDL QWADLASLKL IQLLAINSDI QYLFLIGAYR DNEVDDSHHL
510 520 530 540 550
MLVLQEIEQK CIPINIIYCQ NLKITDVCQL VSDTLKSGLE ESKELAKLIF
560 570 580 590 600
HKTAGNPFFV NQLLKFIHQE NLLVFNFITG QWQWYIQYIQ MLDITDNVVD
610 620 630 640 650
LMIGKIQKLK DNTQNIIKIA ACIGNRFNLN TLSCINEKSH NATALDIWEA
660 670 680 690 700
LQAGLIIPLS DNYKLPQLLD DVDVFVIDYK FLHDRVQQAA YALIPDEHKK
710 720 730 740 750
GIHLNIGRLL LKNINKSLLE EKIFDIANQL NMGAELITVP EERYKLASLN
760 770 780 790 800
LMAGRKAKDS NAYESAVSFL KQGLTLLDID CWQNYYELTL DLHVETVESE
810 820 830 840 850
YLNTNFEEAE PLLATVIANS KNILDTVKVY EKKIQFYVGQ NRMREALDLD
860 870 880 890 900
LQVLEMLGVS LSQTPPTELK IEELINLPEM IDPSKLAAMR ILMTAMPPAY
910 920 930 940 950
LADPALLPLI AFTMIELCLQ YGNSSFAAYA YGFYGLILCG PLKNIESGYR
960 970 980 990 1000
FGKLSLQILN QFNAKEIKSK VYALFNIFVR HWKEHIQTTI EPLQEGVKSG
1010 1020 1030 1040 1050
LDTGDIEYVG YNGLLVCWHP FWSGENLETV EQRLDKYINL AQKIQQEHFT
1060 1070 1080 1090 1100
FCLLILKQLI TELKQGLKNE VYLDGDDFND SIMQRMAGNI TAIFYAYLAK
1110 1120 1130 1140 1150
SMLSYFFKDY SQAVKNAELA QQYEVAVGGT FYLIEYKFYY SLGLLALCLN
1160 1170 1180 1190 1200
TTSDADIKSA LEKVSENQQQ LKEWADHAPA NNQHKYELVE AEKARVLGQV
1210 1220 1230 1240 1250
LIAMEYYECA IQGAHKFGYI HEEALAYECA AEFYFSLKRN EFACLYITKA
1260 1270 1280 1290 1300
HYGYRHWGAI AKARNLESKY PELTAKISNQ YPAGFINTNI TTSTASEKSG
1310 1320 1330 1340 1350
GLDLITVIKA SQTLSEVILL DNLLEKLMTI LIENAGAQTG ILLLEKAGNL
1360 1370 1380 1390 1400
LIEAKASVDK DDITVGQSIP FEDSQQLPIS VINFVRRTRK DVVLSDASNE
1410 1420 1430 1440 1450
GSFTLDPYIV KHNIKSIICT SILNQGKLIG ILYLENNLIV GAFTADRIQI
1460 1470 1480 1490 1500
LKLLSSQAAI SLENAQLYAN LEEKIEERTR ELNENNLRLR QTLHELKLTQ
1510 1520 1530 1540 1550
TQLIQTEKMS SLGQMVAGIA HEINNPVSFI HGNLSHIDNY ANDLLTLIDI
1560 1570 1580 1590 1600
YQTIYPEATP EIEEFLENID VDFIKEDMPK TLSSMKIGTQ RIREIVLTLR
1610 1620 1630 1640 1650
NFSRLDEAEM KAVNIHEGIE STLLILQSRL QAKPGKPAIE IIKNYAELPK
1660 1670 1680 1690 1700
VECYTGQLNQ VFMNILNNAI DSLEKLNQEH NLEEIKTDPS AIAIRTEVVN
1710 1720 1730 1740 1750
PDLVAISIKD NGLGMSDSVR KRIFDPFFTT KPIGQGTGLG LSISYQIVVD
1760 1770 1780
KHRGTIECIS TPGQGAEFII QIPCRQKQVI
Length:1,780
Mass (Da):201,834
Last modified:October 25, 2005 - v1
Checksum:i60B9FAA3A2A12CFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA19709.1.
RefSeqiYP_320604.1. NC_007413.1.

Genome annotation databases

EnsemblBacteriaiABA19709; ABA19709; Ava_0083.
KEGGiava:Ava_0083.
PATRICi35420415. VBIAnaVar43351_0782.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA19709.1.
RefSeqiYP_320604.1. NC_007413.1.

3D structure databases

ProteinModelPortaliQ3MH27.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA19709; ABA19709; Ava_0083.
KEGGiava:Ava_0083.
PATRICi35420415. VBIAnaVar43351_0782.

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000263148.
OMAiPLIAFTM.
OrthoDBiEOG6HTNS7.

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-83-MONOMER.

Family and domain databases

Gene3Di3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Anabaena variabilis ATCC 29413."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29413 / PCC 7937Imported.

Entry informationi

Entry nameiQ3MH27_ANAVT
AccessioniPrimary (citable) accession number: Q3MH27
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: April 1, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.