Q3MH12 (Q3MH12_ANAVT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ABA19724.1
EC=2.4.1.182 EMBL ABA19724.1

Gene names

Ordered Locus Names:

Ava_0098

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]

Taxonomic identifier

240292 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	384 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ABA19724.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3MH12 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: 869DBBAE132A33EA	FASTA	384	42,314
	10 20 30 40 50 60 MRIFISTGEV SGDLQGALLI AALKRQAVAM GMELEIVALG GDKMAAAGAT ILGNTSGIGS 70 80 90 100 110 120 MGIFESLPYV LPTLIVQRRA IAYLKQNPPD LVVLIDYMGP NLGVGTYMQN HLPNVPVVYY 130 140 150 160 170 180 IAPQEWVWSM SLRNTSRIVG FTDKLLAIFP EEARYFSNNG ANVTWVGHPL LDRMQDVPSR 190 200 210 220 230 240 EEARANLGIT PEQKAIALLP ASRRQELKYL LPIIFQSAQT IQAKLPEAHF WIPLSLEVYR 250 260 270 280 290 300 QPIEAAIKAY GLQATVVSGQ QKEVFAAADI AITKSGTVNL ELALLNVPQV VVYRLHPVTV 310 320 330 340 350 360 WIARKILKGS IPFASPPNLV VMKPIVPELL QEQATPENIT QAAMELLLNC ERRQQTLADY 370 380 HEMRQCLGEL GVCDRAAQEI LQML

References

[1]

"Complete sequence of Anabaena variabilis ATCC 29413." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000117 Genomic DNA. Translation: ABA19724.1.
RefSeq	YP_320619.1. NC_007413.1.
3D structure databases
ProteinModelPortal	Q3MH12.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3MH12.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3683373.
GenomeReviews	Gene locus Ava_0098 in contig CP000117_GR.
KEGG	ava:Ava_0098.
NMPDR	fig|240292.3.peg.419.
PATRIC	35420451. VBIAnaVar43351_0800.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0763.
HOGENOM	HBG584837.
OMA	PDFNLGL.
PhylomeDB	Q3MH12.
ProtClustDB	PRK00025.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3MH12_ANAVT

Accession

Primary (citable) accession number: Q3MH12

Entry history

Integrated into UniProtKB/TrEMBL:	October 25, 2005
Last sequence update:	October 25, 2005
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)