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Q3MFX2 (ACKA_ANAVT) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:Ava_0490
OrganismAnabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]
Taxonomic identifier240292 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Acetate kinase HAMAP MF_00020
PRO_1000002205

Sequences

Sequence LengthMass (Da)Tools
Q3MFX2 [UniParc].

Last modified October 25, 2005. Version 1.
Checksum: AD946DFBEFC6ED3F

FASTA40543,873
        10         20         30         40         50         60 
MKVLILNAGS SSQKSCLYEI PDDALLTEAP QPLWEGKVNW TQDRSVAEIE VKTAGGETLH 

        70         80         90        100        110        120 
ESIYGDSRQA HVTYMLYTLS RGTTKVIGQL SEIDVVGHRV VHGGQNYRNS VIITEEVKQA 

       130        140        150        160        170        180 
IAKLSNLAPA HNPAALEGIE AIEKSLGDVP QVAVFDTGFH ATLPDAAAIY PGPFEWVEQG 

       190        200        210        220        230        240 
IRRYGFHGIS HQYCSARAAQ ILGRDLASLR IITCHLGNGC SLAAIKNGRS IDTTMGFTPL 

       250        260        270        280        290        300 
DGLMMGSRSG SIDPGIIVHL MRQSDYSAER LDYVLNKASG LRGISGVSSD LPQVIEAITQ 

       310        320        330        340        350        360 
GNYRAQLAWD MYVHRLRSGI GSMLASLGGL DVLVFTAGVG EKSPGIRQAA CEAFGFLGLK 

       370        380        390        400 
LDPEKNQNNP VDIDIATADS TVRVLVIHTQ EDWAIAQQCW HLLNR

« Hide

References

[1]"Complete sequence of Anabaena variabilis ATCC 29413."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000117 Genomic DNA. Translation: ABA20114.1.
RefSeqYP_321009.1. NC_007413.1.

3D structure databases

ProteinModelPortalQ3MFX2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3MFX2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3682397.
GenomeReviewsGene locus Ava_0490 in contig CP000117_GR.
KEGGava:Ava_0490.
NMPDRfig|240292.3.peg.1848.
PATRIC35421336. VBIAnaVar43351_1240.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0282.
HOGENOMHBG285863.
OMAYLPEARI.
PhylomeDBQ3MFX2.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycAVAR240292:AVA_0490-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_ANAVT
AccessionPrimary (citable) accession number: Q3MFX2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 25, 2005
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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