Reviewed, UniProtKB/Swiss-Prot Q3MFX2 (ACKA_ANAVT)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	Ava_0490

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]

Taxonomic identifier

240292 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	405 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 405	405	Acetate kinase HAMAP MF_00020		PRO_1000002205

Sequences

	Sequence		Length	Mass (Da)
	Q3MFX2-1 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: AD946DFBEFC6ED3F	FASTA	405	43,873
	10 20 30 40 50 60 MKVLILNAGS SSQKSCLYEI PDDALLTEAP QPLWEGKVNW TQDRSVAEIE VKTAGGETLH 70 80 90 100 110 120 ESIYGDSRQA HVTYMLYTLS RGTTKVIGQL SEIDVVGHRV VHGGQNYRNS VIITEEVKQA 130 140 150 160 170 180 IAKLSNLAPA HNPAALEGIE AIEKSLGDVP QVAVFDTGFH ATLPDAAAIY PGPFEWVEQG 190 200 210 220 230 240 IRRYGFHGIS HQYCSARAAQ ILGRDLASLR IITCHLGNGC SLAAIKNGRS IDTTMGFTPL 250 260 270 280 290 300 DGLMMGSRSG SIDPGIIVHL MRQSDYSAER LDYVLNKASG LRGISGVSSD LPQVIEAITQ 310 320 330 340 350 360 GNYRAQLAWD MYVHRLRSGI GSMLASLGGL DVLVFTAGVG EKSPGIRQAA CEAFGFLGLK 370 380 390 400 LDPEKNQNNP VDIDIATADS TVRVLVIHTQ EDWAIAQQCW HLLNR

References

[1]

"Complete sequence of Anabaena variabilis ATCC 29413." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000117 Genomic DNA. Translation: ABA20114.1.
RefSeq	YP_321009.1.
3D structure databases
SMR	Q3MFX2. Positions 1-405.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3MFX2.
Genome annotation databases
GeneID	3682397.
GenomeReviews	Gene locus Ava_0490 in contig CP000117_GR.
KEGG	ava:Ava_0490.
NMPDR	fig|240292.3.peg.1848.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0282.
HOGENOM	HBG285863.
OMA	IVTFLME.
PhylomeDB	Q3MFX2.
Enzyme and pathway databases
BioCyc	AVAR240292:AVA_0490-MONOMER.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_ANAVT

Accession

Primary (citable) accession number: Q3MFX2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 25, 2005
Last modified:	February 9, 2010
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)