Q3MFW5 (COMB_ANAVT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	Ava_0497

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]

Taxonomic identifier

240292 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 245	245	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000014459

Sequences

	Sequence		Length	Mass (Da)
	Q3MFW5 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: 7559BA13E24A4B44	FASTA	245	26,622
	10 20 30 40 50 60 MKLFVYHTPE LTPKDQVPDC AIAVDVLRAT STIATVLSAG GEAVQVFSDL DELIAVSETW 70 80 90 100 110 120 PPQKRLRAGE RGGGKVAGFE LGNSPLDCTP ELVEGRRLFI STTNGTRALK RVQDSATVLT 130 140 150 160 170 180 AAFINRAAVV QYLLEKQPET VWIVGSGWEG SYSLEDTACA GAIAHSVVEK SQLPPEKLAG 190 200 210 220 230 240 NDEVISAIAL YSQWQDNLLG LLHHASHGQR LLRLECHEDL KYCSQTDVLT VLPIQQEAGV FKTKN

References

[1]

"Complete sequence of Anabaena variabilis ATCC 29413." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000117 Genomic DNA. Translation: ABA20121.1.
RefSeq	YP_321016.1. NC_007413.1.
3D structure databases
ProteinModelPortal	Q3MFW5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3MFW5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3682404.
GenomeReviews	Gene locus Ava_0497 in contig CP000117_GR.
KEGG	ava:Ava_0497.
NMPDR	fig|240292.3.peg.1855.
PATRIC	35421354. VBIAnaVar43351_1249.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2045.
HOGENOM	HBG633644.
OMA	GWEGAYS.
PhylomeDB	Q3MFW5.
ProtClustDB	PRK00886.
Enzyme and pathway databases
BioCyc	AVAR240292:AVA_0497-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_ANAVT

Accession

Primary (citable) accession number: Q3MFW5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 25, 2005
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program