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Q3MFM3 (AROC_ANAVT) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:Ava_0589
OrganismAnabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]
Taxonomic identifier240292 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 362362Chorismate synthase HAMAP MF_00300
PRO_0000256270

Sequences

Sequence LengthMass (Da)Tools
Q3MFM3 [UniParc].

Last modified October 25, 2005. Version 1.
Checksum: 4DD32588F01C22FC

FASTA36239,339
        10         20         30         40         50         60 
MGNTFGHLFR ITTFGESHGG GVGVVIDGCP PLLEISPEEI QLELDRRRPG QSKITTPRKE 

        70         80         90        100        110        120 
ADTCEILSGV YEGKTLGTPI SILVRNKDTR PQDYDEMAQK YRPSHADATY DAKYGIRNWQ 

       130        140        150        160        170        180 
GGGRSSARET IGRVAAGAIA KKILRQVANV EVIGYVKRIK DLEGVVDPNT VTLDQVESNI 

       190        200        210        220        230        240 
VRCPDGELAD RMIELIEQTG RQGDSIGGVV ECVARNVPKG LGEPVFDKLE ADIAKAVMSL 

       250        260        270        280        290        300 
PASKGFEIGS GFAGTLLTGF EHNDEYYIDE NGEIRTVTNR SGGIQGGIAN GENIILRVAF 

       310        320        330        340        350        360 
KPTATIRKEQ KTVTREGEET LLAAKGRHDP CVLPRAVPMV EAMVALVLCD HLLRHHGQCK 


VL

« Hide

References

[1]"Complete sequence of Anabaena variabilis ATCC 29413."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000117 Genomic DNA. Translation: ABA20213.1.
RefSeqYP_321108.1. NC_007413.1.

3D structure databases

HSSPHSSP built from PDB template 1ZTB based on UniProtKB P63611.
ProteinModelPortalQ3MFM3.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3MFM3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3678619.
GenomeReviewsGene locus Ava_0589 in contig CP000117_GR.
KEGGava:Ava_0589.
PATRIC35421566. VBIAnaVar43351_1354.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
OMAGVQGGIS.
PhylomeDBQ3MFM3.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycAVAR240292:AVA_0589-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_ANAVT
AccessionPrimary (citable) accession number: Q3MFM3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 25, 2005
Last modified: January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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