Reviewed, UniProtKB/Swiss-Prot Q3MF82 (DEOC_ANAVT)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase
      Short name=Deoxyriboaldolase
      Short name=DERA

Gene names

Name:	deoC
Ordered Locus Names:	Ava_0730

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]

Taxonomic identifier

240292 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	226 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity HAMAP MF_00114.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 226	226	Deoxyribose-phosphate aldolase HAMAP MF_00114		PRO_0000231527
Sites
	Active site	157	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	185	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3MF82-1 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: CE7FC0A0D140892D	FASTA	226	24,452
	10 20 30 40 50 60 MAADYPNIDI APFIDHALLT PTATPEQVDQ WCEQADRYNF ASVCLYPTYV KQAAEFLHGK 70 80 90 100 110 120 KPKVCTVIGF PTGATTRSVK LYEALEAVEN GATELDVVIN LGCLKSGNTE AVHREIAEIC 130 140 150 160 170 180 EETGQVVKVI LETNLLTDAE KKIAADIAMD AGATFLKTNT GWNGGATVAD VRLLKEITRE 190 200 210 220 RVGIKASGGI RTLNQALDLI LAGATRLGTS RGIDLIHQRD NPEKVE

References

[1]

"Complete sequence of Anabaena variabilis ATCC 29413." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000117 Genomic DNA. Translation: ABA20354.1.
RefSeq	YP_321249.1.
3D structure databases
SMR	Q3MF82. Positions 7-218.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3MF82.
Genome annotation databases
GeneID	3679385.
GenomeReviews	Gene locus Ava_0730 in contig CP000117_GR.
KEGG	ava:Ava_0730.
NMPDR	fig|240292.3.peg.1329.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0274.
HOGENOM	HBG636421.
OMA	AKMIDHT.
PhylomeDB	Q3MF82.
Enzyme and pathway databases
BioCyc	AVAR240292:AVA_0730-MONOMER.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC_ANAVT

Accession

Primary (citable) accession number: Q3MF82

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	October 25, 2005
Last modified:	February 9, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)