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Q3MF40 (PGK_ANAVT) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:Ava_0772
OrganismAnabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]
Taxonomic identifier240292 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaNostocalesNostocaceaeAnabaena

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000057959

Regions

Nucleotide binding356 – 3594ATP By similarity
Region24 – 263Substrate binding By similarity
Region63 – 664Substrate binding By similarity

Sites

Binding site401Substrate By similarity
Binding site1211Substrate By similarity
Binding site1541Substrate By similarity
Binding site2051ATP By similarity
Binding site2961ATP; via carbonyl oxygen By similarity
Binding site3271ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q3MF40 [UniParc].

Last modified October 25, 2005. Version 1.
Checksum: 3B7DF324A5A21178

FASTA40042,441
        10         20         30         40         50         60 
MSKKTVASLS AADISGKRAL VRVDFNVPLD DQGNITDDTR IRAALPTIQD LTQKGAKVIL 

        70         80         90        100        110        120 
ASHFGRPKGV DEKLRLTPVA KRLSELLGQE VVKTDDSIGD EVAAKVAALQ NGQVLLLENV 

       130        140        150        160        170        180 
RFYKEEEKND PEFAKKLAAN ADFYVNDAFG TAHRAHASTE GVTKFLSPSV AGYLVEKELQ 

       190        200        210        220        230        240 
YLQSAIENPQ RPLAAIIGGS KVSSKIGVIE TLLEKCDKLI IGGGMIFTFY KARGLNVGKS 

       250        260        270        280        290        300 
LVEEDKLELA KSLEAKAKER GVSLLLPTDV VLADNFAPDA NSQTVSIDNI PDGWMGLDIG 

       310        320        330        340        350        360 
PDSVKVFQEA LADTKTVIWN GPMGVFEFDK FAAGTEAIAH TLAEIGKTGT TTIIGGGDSV 

       370        380        390        400 
AAVEKVGLAD QMSHISTGGG ASLELLEGKV LPGIAALDEA 

« Hide

References

[1]"Complete sequence of Anabaena variabilis ATCC 29413."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000117 Genomic DNA. Translation: ABA20396.1.
RefSeqYP_321291.1. NC_007413.1.

3D structure databases

ProteinModelPortalQ3MF40.
SMRQ3MF40. Positions 1-399.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING240292.Ava_0772.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA20396; ABA20396; Ava_0772.
GeneID3680359.
KEGGava:Ava_0772.
PATRIC35421956. VBIAnaVar43351_1548.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMAMSIRYID.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycAVAR240292:GCY3-776-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_ANAVT
AccessionPrimary (citable) accession number: Q3MF40
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 25, 2005
Last modified: June 11, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways