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Protein

Glucokinase

Gene

glk

Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi7 – 126ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-943-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
Alternative name(s):
Glucose kinaseUniRule annotation
Gene namesi
Name:glkUniRule annotation
Ordered Locus Names:Ava_0933
OrganismiAnabaena variabilis (strain ATCC 29413 / PCC 7937)
Taxonomic identifieri240292 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeAnabaena
ProteomesiUP000002533: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 342342GlucokinasePRO_0000268766Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi240292.Ava_0933.

Structurei

3D structure databases

ProteinModelPortaliQ3MEM9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274470.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3MEM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLLLAGDIG GTKTILRLVE VSNSSELHNI YEESYQSGDF PDLVPMVQQF
60 70 80 90 100
LVKANIPSHP EKACFAIAGP VVNNTAKLTN LVWFLDTERL AQELSIPFIS
110 120 130 140 150
LINDFAAVGY GIFGLSKQDL FTLQAGKHQT EAPIAIIGAG TGLGQGFLIK
160 170 180 190 200
QGNQYQVFPS EGGHADFAPR NELEFQLLKY LLDKHDIQRV SVERVVSGQG
210 220 230 240 250
VVAIYQFLRD RKLAIESPEI AQVVRTWEQQ AGQAEKTVDP GAAIGKAAVQ
260 270 280 290 300
GSDRLSEQTL QLFIDAYGAE AGNLALKLLP YGGLYIAGGI APKVLPLIEN
310 320 330 340
SNFLLNFSQK GRMRPLLEEI PVHIILNPQV GLIGAALCAA RL
Length:342
Mass (Da):37,102
Last modified:October 25, 2005 - v1
Checksum:i1C22C580A0603D81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA20557.1.
RefSeqiYP_321452.1. NC_007413.1.

Genome annotation databases

EnsemblBacteriaiABA20557; ABA20557; Ava_0933.
GeneIDi3681307.
KEGGiava:Ava_0933.
PATRICi35422314. VBIAnaVar43351_1722.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA20557.1.
RefSeqiYP_321452.1. NC_007413.1.

3D structure databases

ProteinModelPortaliQ3MEM9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi240292.Ava_0933.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA20557; ABA20557; Ava_0933.
GeneIDi3681307.
KEGGiava:Ava_0933.
PATRICi35422314. VBIAnaVar43351_1722.

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274470.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-943-MONOMER.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Anabaena variabilis ATCC 29413."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29413 / PCC 7937.

Entry informationi

Entry nameiGLK_ANAVT
AccessioniPrimary (citable) accession number: Q3MEM9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 25, 2005
Last modified: March 4, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.