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Q3MEJ6

- GLSA_ANAVT

UniProt

Q3MEJ6 - GLSA_ANAVT

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Protein

Glutaminase

Gene
glsA, Ava_0966
Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei76 – 761Substrate By similarity
Binding sitei126 – 1261Substrate By similarity
Binding sitei170 – 1701Substrate By similarity
Binding sitei177 – 1771Substrate By similarity
Binding sitei201 – 2011Substrate By similarity
Binding sitei253 – 2531Substrate By similarity
Binding sitei271 – 2711Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-976-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Ava_0966
OrganismiAnabaena variabilis (strain ATCC 29413 / PCC 7937)
Taxonomic identifieri240292 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeAnabaena
ProteomesiUP000002533: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 334334GlutaminaseUniRule annotationPRO_1000048321Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi240292.Ava_0966.

Structurei

3D structure databases

ProteinModelPortaliQ3MEJ6.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQCSVGVT.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3MEJ6-1 [UniParc]FASTAAdd to Basket

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MSDQANQGDL EIRPSPLLTV INDLHSKYKS LKEGIVANYI PELAKVNPDL    50
FSISIVTVDG QVYQVGDYQQ LFTIQSISKV FAYGLALEDH GRDYVLTRVG 100
VEPTGEAFNS IILDEQSKRP YNPMVNAGAI ATTSLIKGAG ATERLNRVLE 150
MFRRYIGHDV FVDISVFTSE RSTGHRNRAM AHLMLNFGMI DRNLEEALDL 200
YFQQCAVMVN CHDLAVMAAT LANRGVNPVT GEQAVNSRYI KDILSVMYTC 250
GMYNFAGEWA YKVGIPAKSG VCGGIMAVVP NQMGIAVFSP PLDIRGNSVR 300
GVKVCEELSQ QLGLHLFECV KVENGKWGVG NCEC 334
Length:334
Mass (Da):36,741
Last modified:October 25, 2005 - v1
Checksum:iDE0D6CAC4F7BA825
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000117 Genomic DNA. Translation: ABA20590.1.
RefSeqiYP_321485.1. NC_007413.1.

Genome annotation databases

EnsemblBacteriaiABA20590; ABA20590; Ava_0966.
GeneIDi3680229.
KEGGiava:Ava_0966.
PATRICi35422390. VBIAnaVar43351_1760.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000117 Genomic DNA. Translation: ABA20590.1 .
RefSeqi YP_321485.1. NC_007413.1.

3D structure databases

ProteinModelPortali Q3MEJ6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 240292.Ava_0966.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA20590 ; ABA20590 ; Ava_0966 .
GeneIDi 3680229.
KEGGi ava:Ava_0966.
PATRICi 35422390. VBIAnaVar43351_1760.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QCSVGVT.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci AVAR240292:GCY3-976-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Anabaena variabilis ATCC 29413."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29413 / PCC 7937.

Entry informationi

Entry nameiGLSA_ANAVT
AccessioniPrimary (citable) accession number: Q3MEJ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 25, 2005
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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