Q3MDY2 (Q3MDY2_ANAVT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 1 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 1 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 1 HAMAP MF_01401

Gene names

Name:	msrA1 HAMAP MF_01401
Ordered Locus Names:	Ava_1180

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]

Taxonomic identifier

240292 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	222 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL ABA20804.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	56	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q3MDY2 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: 9365D5B52640928B	FASTA	222	24,345
	10 20 30 40 50 60 MALFGFGKKL ALPTPEKALP GRAQIMPVPA NHYVNKNPLK PPFPEGFEKA LFGLGCFWGA 70 80 90 100 110 120 ERKFWQQSGV YTTAVGYAAG FTPNPTYDEV CTGLTGHNEV VLVVFDPKVI SYTQLLKVFW 130 140 150 160 170 180 ESHNPTQGMR QGNDVGTQYR SGIYVYSEAQ KQLAEASRDA YQQALSSAGY EKITTEILDA 190 200 210 220 PEFYYAEAYH QQYLAKNPNG YCGLGGTNVA CPVGVFESSA NG

References

[1]

"Complete sequence of Anabaena variabilis ATCC 29413." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000117 Genomic DNA. Translation: ABA20804.1.
RefSeq	YP_321699.1. NC_007413.1.
3D structure databases
ProteinModelPortal	Q3MDY2.
SMR	Q3MDY2. Positions 14-212.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3MDY2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3683318.
GenomeReviews	Gene locus Ava_1180 in contig CP000117_GR.
KEGG	ava:Ava_1180.
NMPDR	fig|240292.3.peg.1864.
PATRIC	35422878. VBIAnaVar43351_2001.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HBG748152.
OMA	SAIYCTT.
PhylomeDB	Q3MDY2.
ProtClustDB	PRK00058.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3MDY2_ANAVT

Accession

Primary (citable) accession number: Q3MDY2

Entry history

Integrated into UniProtKB/TrEMBL:	October 25, 2005
Last sequence update:	October 25, 2005
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)