ID   ARLY_ANAVT              Reviewed;         461 AA.
AC   Q3MC57;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   16-JUN-2009, entry version 32.
DE   RecName: Full=Argininosuccinate lyase;
DE            Short=ASAL;
DE            EC=4.3.2.1;
DE   AltName: Full=Arginosuccinase;
GN   Name=argH; OrderedLocusNames=Ava_1807;
OS   Anabaena variabilis (strain ATCC 29413 / PCC 7937).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Anabaena.
OX   NCBI_TaxID=240292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.;
RT   "Complete sequence of Anabaena variabilis ATCC 29413.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: 2-(N(omega)-L-arginino)succinate = fumarate +
CC       L-arginine.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-
CC       arginine from L-ornithine and carbamoyl phosphate: step 3/3.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the lyase 1 family. Argininosuccinate lyase
CC       subfamily.
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DR   EMBL; CP000117; ABA21429.1; -; Genomic_DNA.
DR   RefSeq; YP_322324.1; -.
DR   GeneID; 3681974; -.
DR   GenomeReviews; CP000117_GR; Ava_1807.
DR   KEGG; ava:Ava_1807; -.
DR   NMPDR; fig|240292.3.peg.2887; -.
DR   HOGENOM; Q3MC57; -.
DR   OMA; Q3MC57; MAEDLIF.
DR   BioCyc; AVAR240292:AVA_1807-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004056; F:argininosuccinate lyase activity; IEA:HAMAP.
DR   GO; GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro.
DR   HAMAP; MF_00006; -; 1.
DR   InterPro; IPR009049; Argininosuccinate_lyase.
DR   InterPro; IPR003031; D_crystallin.
DR   InterPro; IPR000362; Fumarate_lyase.
DR   PANTHER; PTHR11444:SF3; argH; 1.
DR   Pfam; PF00206; Lyase_1; 1.
DR   PRINTS; PR00145; DCRYSTALLIN.
DR   PRINTS; PR00149; FUMRATELYASE.
DR   TIGRFAMs; TIGR00838; argH; 1.
DR   PROSITE; PS00163; FUMARATE_LYASES; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome;
KW   Cytoplasm; Lyase.
FT   CHAIN         1    461       Argininosuccinate lyase.
FT                                /FTId=PRO_0000240709.
SQ   SEQUENCE   461 AA;  51627 MW;  5A9438DCF7A25E10 CRC64;
     MTEKQTWSQR FESALHPAIA LFNASISFDI ELIEYDLTGS QAHAQMLAHT GIISPAEGEQ
     LVAGLEQIRE EYRQGKFQPG IDAEDVHFAV ERRLTEIVGD VGKKLHTARS RNDQVGTDTR
     LYLRDQISQI KTQLREFQRV LLDIAEQNVE TLIPGYTHLQ RAQPVSLAHH LLAYFHMAQR
     DWERLGDVYR RVNISPLGCG ALAGTTFPID RHYTAKLLQF ERIYENSLDG VSDRDFAIEF
     LCAASLIMVH LSRLSEEIIL WASEEFRFVT LKDSCATGSS IMPQKKNPDV PELVRGKTGR
     VFGHLQAMLV IMKGLPLAYN KDLQEDKEGL FDSVNTVKAC LEAMTILLQE GLEFRTQRLA
     EAVTQDFSNA TDVADYLAAR GVPFREAYNI VGKVVKTSIA AGKLLKDLTL EEWQEIHPAF
     ATDIYEAISP RQVVAARNSY GGTGFAQVSK AVSAAREEIG E
//